Cancer Institute of New Jersey (CINJ), Department of Medicine

Research Output

  • 1151 Citations
  • 18 h-Index
  • 25 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Letter
2020

Author Correction: Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans (Nature Communications, (2019), 10, 1, (5735), 10.1038/s41467-019-13732-y)

Mitchell, K. A., Nichols, N., Tang, W., Walling, J., Stevenson, H., Pineda, M., Stefanescu, R., Edelman, D. C., Girvin, A. T., Zingone, A., Sinha, S., Bowman, E., Rossi, E. L., Arauz, R. F., Zhu, Y. J., Lack, J., Weingartner, E., Waterfall, J. J., Pine, S. R., Simmons, J. & 2 others, Meltzer, P. & Ryan, B. M., Dec 1 2020, In : Nature communications. 11, 1, 700.

Research output: Contribution to journalComment/debate

Open Access
2019

Circulating Inflammation Proteins Associated With Lung Cancer in African Americans

Meaney, C. L., Mitchell, K. A., Zingone, A., Brown, D., Bowman, E., Yu, Y., Wenzlaff, A. S., Neslund-Dudas, C., Pine, S., Cao, L., Schwartz, A. G. & Ryan, B. M., Jul 1 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1192-1203 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
1 Scopus citations

Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans

Mitchell, K. A., Nichols, N., Tang, W., Walling, J., Stevenson, H., Pineda, M., Stefanescu, R., Edelman, D. C., Girvin, A. T., Zingone, A., Sinha, S., Bowman, E., Rossi, E. L., Arauz, R. F., Jack Zhu, Y., Lack, J., Weingartner, E., Waterfall, J., Pine, S. R., Simmons, J. & 2 others, Meltzer, P. & Ryan, B. M., Dec 1 2019, In : Nature communications. 10, 1, 5735.

Research output: Contribution to journalArticle

Open Access
2018

Identifying therapeutic vulnerabilities in lung cancer: Application of a chemistry-first approach

Pine, S. R. & Ryan, B. M., Sep 1 2018, In : Translational Lung Cancer Research. 7, p. S265-S269

Research output: Contribution to journalReview article

Rethinking Gamma-secretase Inhibitors for Treatment of Non–small-Cell Lung Cancer: Is notch the target?

Pine, S. R., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6136-6141 6 p.

Research output: Contribution to journalReview article

3 Scopus citations

Utility of glioblastoma patient-derived orthotopic xenografts in drug discovery and personalized therapy

Patrizii, M., Bartucci, M., Pine, S. & Sabaawy, H., Feb 12 2018, In : Frontiers in Oncology. 8, FEB, 23.

Research output: Contribution to journalArticle

20 Scopus citations
2017

BRAF fusion as a novel mechanism of acquired resistance to vemurafenib in BRAFV600E mutant melanoma

Kulkarni, A., Al-Hraishawi, H., Simhadri, S., Hirshfield, K. M., Chen, S., Pine, S., Jeyamohan, C., Sokol, L., Ali, S., Teo, M. L., White, E., Rodriguez-Rodriguez, L., Mehnert, J. M. & Ganesan, S., Sep 15 2017, In : Clinical Cancer Research. 23, 18, p. 5631-5638 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Gamma secretase inhibition by BMS-906024 enhances efficacy of paclitaxel in lung adenocarcinoma

Morgan, K. M., Fischer, B. S., Lee, F. Y., Shah, J. J., Bertino, J., Rosenfeld, J., Singh, A., Khiabanian, H. & Pine, S., Dec 2017, In : Molecular cancer therapeutics. 16, 12, p. 2759-2769 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Patient-derived xenograft models of non-small cell lung cancer and their potential utility in personalized medicine

Morgan, K. M., Riedlinger, G. M., Rosenfeld, J., Ganesan, S. & Pine, S. R., Jan 19 2017, In : Frontiers in Oncology. 7, JAN, 2.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Differential serum cytokine levels and risk of lung cancer between African and European Americans

Pine, S. R., Mechanic, L. E., Enewold, L., Bowman, E. D., Ryan, B. M., Cote, M. L., Wenzlaff, A. S., Loffredo, C. A., Olivo-Marston, S., Chaturvedi, A., Caporaso, N. E., Schwartz, A. G. & Harris, C. C., Mar 2016, In : Cancer Epidemiology Biomarkers and Prevention. 25, 3, p. 488-497 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage

Hong, X., Liu, W., Song, R., Shah, J. J., Feng, X., Tsang, C. K., Morgan, K. M., Bunting, S., Inuzuka, H., Zheng, X. F. S., Shen, Z., Sabaawy, H., Liu, L. X. & Pine, S., Oct 14 2016, In : Nucleic acids research. 44, 18, p. 8855-8869 15 p.

Research output: Contribution to journalArticle

19 Scopus citations
2015

Identification of a functional SNP in the 3′UTR of CXCR2 that is associated with reduced risk of lung cancer

Ryan, B. M., Robles, A. I., McClary, A. C., Haznadar, M., Bowman, E. D., Pine, S. R., Brown, D., Khan, M., Shiraishi, K., Kohno, T., Okayama, H., Modali, R., Yokota, J. & Harris, C. C., Feb 1 2015, In : Cancer Research. 75, 3, p. 566-575 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
2014

A combined prognostic serum interleukin-8 and interleukin-6 classifier for stage 1 lung cancer in the prostate, lung, colorectal, and ovarian cancer screening trial

Ryan, B. M., Pine, S. R., Chaturvedi, A. K., Caporaso, N. & Harris, C. C., Oct 1 2014, In : Journal of Thoracic Oncology. 9, 10, p. 1494-1503 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Activation of the Notch1 stem cell signaling pathway during routine cell line subculture

Liu, W., Morgan, K. M. & Pine, S. R., Jan 1 2014, In : Frontiers in Oncology. 4 JUL, 211.

Research output: Contribution to journalComment/debate

5 Scopus citations

Asymmetric cell division and template DNA co-segregation in cancer stem cells

Pine, S. R. & Liu, W., Jan 1 2014, In : Frontiers in Oncology. 4 AUG, Article 226.

Research output: Contribution to journalArticle

12 Scopus citations

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma

Capaccione, K. M., Hong, X., Morgan, K. M., Liu, W., Bishop, M. J., Liu, L. X., Markert, E., Deen, M., Minerowicz, C., Allen, T. & Pine, S. R., 2014, In : Oncotarget. 5, 11, p. 3636-3650 15 p.

Research output: Contribution to journalArticle

47 Scopus citations
2013

Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines

Liu, W., Jeganathan, G., Amiri, S., Morgan, K. M., Ryan, B. M. & Pine, S. R., Dec 15 2013, In : Molecular Cancer. 12, 1, 139.

Research output: Contribution to journalArticle

10 Scopus citations

P53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes

Mondal, A. M., Horikawa, I., Pine, S. R., Fujita, K., Morgan, K. M., Vera, E., Mazur, S. J., Appella, E., Vojtesek, B., Blasco, M. A., Lane, D. P. & Harris, C. C., Dec 2 2013, In : Journal of Clinical Investigation. 123, 12, p. 5247-5257 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

The Notch signaling pathway as a mediator of tumor survival

Capaccione, K. M. & Pine, S. R., Jul 1 2013, In : Carcinogenesis. 34, 7, p. 1420-1430 11 p.

Research output: Contribution to journalArticle

158 Scopus citations
2012

Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy

Patel, S. A., Ramkissoon, S. H., Bryan, M., Pliner, L. F., Dontu, G., Patel, P. S., Amiri, S., Pine, S. R. & Rameshwar, P., Dec 14 2012, In : Scientific reports. 2, 906.

Research output: Contribution to journalArticle

51 Scopus citations

MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer

Ryan, B. M., Calhoun, K. M., Pine, S. R., Bowman, E. D., Robles, A. I., Ambs, S. & Harris, C. C., Dec 1 2012, In : International Journal of Cancer. 131, 11, p. 2710-2716 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Admixture mapping of lung cancer in 1812 African-Americans

Schwartz, A. G., Wenzlaff, A. S., Bock, C. H., Ruterbusch, J. J., Chen, W., Cote, M. L., Artis, A. S., van Dyke, A. L., Land, S. J., Harris, C. C., Pine, S. R., Spitz, M. R., Amos, C. I., Levin, A. M. & McKeigue, P. M., Mar 10 2011, In : Carcinogenesis. 32, 3, p. 312-317 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Increased levels of circulating interleukin 6, interleukin 8, c-reactive protein, and risk of lung cancer

Pine, S. R., Mechanic, L. E., Enewold, L., Chaturvedi, A. K., Katki, H. A., Zheng, Y. L., Bowman, E. D., Engels, E. A., Caporaso, N. E. & Harris, C. C., Jul 20 2011, In : Journal of the National Cancer Institute. 103, 14, p. 1112-1122 11 p.

Research output: Contribution to journalArticle

188 Scopus citations
2009

p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

Fujita, K., Mondal, A. M., Horikawa, I., Nguyen, G. H., Kumamoto, K., Sohn, J. J., Bowman, E. D., Mathe, E. A., Schetter, A. J., Pine, S. R., Ji, H., Vojtesek, B., Bourdon, J. C., Lane, D. P. & Harris, C. C., Aug 24 2009, In : Nature Cell Biology. 11, 9, p. 1135-1142 8 p.

Research output: Contribution to journalArticle

185 Scopus citations
2007

Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome

Pine, S. R., Guo, Q., Yin, C., Jayabose, S., Druschel, C. M. & Sandoval, C., Sep 15 2007, In : Blood. 110, 6, p. 2128-2131 4 p.

Research output: Contribution to journalArticle

85 Scopus citations

Lymphoproliferative clonal origin of AIDS-related non-Hodgkin's lymphoma [4]

Sabaawy, H., Sandoval, C., Guo, Q., Yin, C., Kulangara, A., Lee, J., Wormser, G., Jayabose, S. & Pine, S., Apr 1 2007, In : Leukemia and Lymphoma. 48, 4, p. 812-815 4 p.

Research output: Contribution to journalLetter

2005

Detection of central nervous system leukemia in children with acute lymphoblastic leukemia by real-time polymerase chain reaction

Pine, S., Yin, C., Matloub, Y. H., Sabaawy, H., Sandoval, C., Levendoglu-Tugal, O., Ozkaynak, M. F. & Jayabose, S., Feb 2005, In : Journal of Molecular Diagnostics. 7, 1, p. 127-132 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome

Pine, S. R., Guo, Q., Yin, C., Jayabose, S., Levendoglu-Tugal, O., Ozkaynak, M. F. & Sandoval, C., Nov 1 2005, In : Leukemia Research. 29, 11, p. 1353-1356 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Tetrasomy 21 transient leukemia with a GATA1 mutation in a phenotypically normal trisomy 21 mosaic infant: Case report and review of the literature

Sandoval, C., Pine, S. R., Guo, Q., Sastry, S., Stewart, J., Kronn, D. & Jayabose, S., Jan 1 2005, In : Pediatric Blood and Cancer. 44, 1, p. 85-91 7 p.

Research output: Contribution to journalReview article

17 Scopus citations
2002

Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia

Wiemels, J. L., Leonard, B. C., Wang, Y., Segal, M. R., Hunger, S. P., Smith, M. T., Crouse, V., Ma, X., Buffler, P. A. & Pine, S. R., Nov 12 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 23, p. 15101-15106 6 p.

Research output: Contribution to journalArticle

86 Scopus citations