Cancer Institute of New Jersey (CINJ), Division of Molecular Oncology

Research Output 2005 2019

2019

Association of JAK2 -V617F Mutations Detected by Solid Tumor Sequencing with Coexistent Myeloproliferative Neoplasms

Riedlinger, G., Hadigol, M., Khiabanian, H. & Ganesan, S., Feb 1 2019, In : JAMA Oncology. 5, 2, p. 265-267 3 p.

Research output: Contribution to journalLetter

Mutation
Neoplasms

PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response

Simhadri, S., Vincelli, G., Huo, Y., Misenko, S., Foo, T. K., Ahlskog, J., Sørensen, C. S., Oakley, G. G., Ganesan, S., Bunting, S. & Xia, B., Mar 7 2019, In : Oncogene. 38, 10, p. 1585-1596 12 p.

Research output: Contribution to journalArticle

Maintenance
Homologous Recombination
DNA Damage
M Phase Cell Cycle Checkpoints
Tumor Suppressor Proteins
2018
7 Citations (Scopus)

Detection of clonal hematopoiesis of indeterminate potential in clinical sequencing of solid tumor specimens

Severson, E. A., Riedlinger, G. M., Connelly, C. F., Vergilio, J. A., Goldfinger, M., Ramkissoon, S., Frampton, G. M., Ross, J. S., Fratella-Calabrese, A., Gay, L., Ali, S., Miller, V., Elvin, J., Hadigol, M., Hirshfield, K., Rodriguez-Rodriguez, L., Ganesan, S. & Khiabanian, H., May 31 2018, In : Blood. 131, 22, p. 2501-2505 5 p.

Research output: Contribution to journalLetter

Hematopoiesis
Neoplasms
3 Citations (Scopus)

Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma

Panda, A., de Cubas, A. A., Stein, M., Riedlinger, G., Kra, J., Mayer, T., Smith, C. C., Vincent, B. G., Serody, J. S., Beckermann, K. E., Ganesan, S., Bhanot, G. & Rathmell, W. K., Aug 23 2018, In : JCI insight. 3, 16

Research output: Contribution to journalArticle

Endogenous Retroviruses
Renal Cell Carcinoma
Neoplasms
Squamous Cell Neoplasms
Atlases
1 Citation (Scopus)

Evidence of intertissue differences in the DNA damage response and the pro-oncogenic role of NF-kB in mice with disengaged BRCA1–PALB2 interaction

Mahdi, A. H., Huo, Y., Tan, Y., Simhadri, S., Vincelli, G., Gao, J., Ganesan, S. & Xia, B., Jul 15 2018, In : Cancer Research. 78, 14, p. 3969-3981 13 p.

Research output: Contribution to journalArticle

NF-kappa B
DNA Damage
Neoplasms
Apoptosis
Recombinational DNA Repair
3 Citations (Scopus)

High-throughput adaptive sampling for whole-slide histopathology image analysis (HASHI) via convolutional neural networks: Application to invasive breast cancer detection

Cruz-Roa, A., Gilmore, H., Basavanhally, A., Feldman, M., Ganesan, S., Shih, N., Tomaszewski, J., Madabhushi, A. & González, F., May 1 2018, In : PloS one. 13, 5, e0196828.

Research output: Contribution to journalArticle

histopathology
breast neoplasms
neural networks
Image analysis
Throughput
19 Citations (Scopus)

Immune activation and benefit from avelumab in EBV-positive gastric cancer

Panda, A., Mehnert, J., Hirshfield, K., Riedlinger, G., Damare, S., Saunders, T., Kane, M., Sokol, L., Stein, M., Poplin, E., Rodriguez-Rodriguez, L., Silk, A., Aisner, J., Chan, N., Malhotra, J., Frankel, M., Kaufman, H. L., Ali, S., Ross, J. S., White, E. P. & 2 othersBhanot, G. & Ganesan, S., Mar 1 2018, In : Journal of the National Cancer Institute. 110, 3, p. 316-320 5 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Stomach Neoplasms
Microsatellite Repeats
Neoplasms
Mutation
4 Citations (Scopus)

Nuclear shape and orientation features from H&E images predict survival in early-stage estrogen receptor-positive breast cancers

Lu, C., Romo-Bucheli, D., Wang, X., Janowczyk, A., Ganesan, S., Gilmore, H., Rimm, D. & Madabhushi, A., Nov 1 2018, In : Laboratory Investigation. 98, 11, p. 1438-1448 11 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Survival
Lymph Nodes
Nonparametric Statistics
1 Citation (Scopus)

Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer

Whitney, J., Corredor, G., Janowczyk, A., Ganesan, S., Doyle, S., Tomaszewski, J., Feldman, M., Gilmore, H. & Madabhushi, A., May 30 2018, In : BMC cancer. 18, 1, 610.

Research output: Contribution to journalArticle

Estrogen Receptors
Area Under Curve
Breast Neoplasms
Discriminant Analysis
Hematoxylin
1 Citation (Scopus)

RET rearrangements are actionable alterations in breast cancer

Paratala, B. S., Chung, J. H., Williams, C. B., Yilmazel, B., Petrosky, W., Williams, K., Schrock, A. B., Gay, L. M., Lee, E., Dolfi, S. C., Pham, K., Lin, S., Yao, M., Kulkarni, A., DiClemente, F., Liu, C., Rodriguez-Rodriguez, L., Ganesan, S., Ross, J. S., Ali, S. M. & 2 othersLeyland-Jones, B. & Hirshfield, K., Nov 16 2018, In : Nature communications. 9, 1, 1 p.

Research output: Contribution to journalArticle

breast
Fusion reactions
fusion
cancer
Breast Neoplasms
2017
52 Citations (Scopus)

Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent

Cruz-Roa, A., Gilmore, H., Basavanhally, A., Feldman, M., Ganesan, S., Shih, N. N. C., Tomaszewski, J., González, F. A. & Madabhushi, A., Apr 18 2017, In : Scientific reports. 7, 46450.

Research output: Contribution to journalArticle

Tumors
Pixels
Pathology
Image analysis
Classifiers
11 Citations (Scopus)

BRAF fusion as a novel mechanism of acquired resistance to vemurafenib in BRAFV600E mutant melanoma

Kulkarni, A., Al-Hraishawi, H., Simhadri, S., Hirshfield, K., Chen, S., Pine, S., Jeyamohan, C., Sokol, L., Ali, S., Teo, M. L., White, E., Rodriguez-Rodriguez, L., Mehnert, J. & Ganesan, S., Sep 15 2017, In : Clinical Cancer Research. 23, 18, p. 5631-5638 8 p.

Research output: Contribution to journalArticle

Melanoma
Gene Fusion
Mitogen-Activated Protein Kinase Kinases
Mutation
PLX4032
9 Citations (Scopus)

Comprehensive genomic profiling of malignant phyllodes tumors of the breast

Nozad, S., Sheehan, C. E., Gay, L. M., Elvin, J. A., Vergilio, J. A., Suh, J., Ramkissoon, S., Schrock, A. B., Hirshfield, K., Ali, N., Ganesan, S., Ali, S. M., Miller, V. A., Stephens, P. J., Ross, J. S. & Chung, J. H., Apr 1 2017, In : Breast Cancer Research and Treatment. 162, 3, p. 597-602 6 p.

Research output: Contribution to journalArticle

Phyllodes Tumor
Breast Neoplasms
Tumor Burden
Microsatellite Repeats
DNA
18 Citations (Scopus)

Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance

Anantha, R. W., Simhadri, S., Foo, T. K., Miao, S., Liu, J., Shen, Z., Ganesan, S. & Xia, B., Apr 11 2017, In : eLife. 6, e21350.

Research output: Contribution to journalArticle

Repair
Recombinational DNA Repair
Ubiquitin-Protein Ligases
Double-Stranded DNA Breaks
Homologous Recombination
21 Citations (Scopus)

Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer

Chung, J. H., Pavlick, D., Hartmaier, R., Schrock, A. B., Young, L., Forcier, B., Ye, P., Levin, M. K., Goldberg, M., Burris, H., Gay, L. M., Hoffman, A. D., Stephens, P. J., Frampton, G. M., Lipson, D. M., Nguyen, D. M., Ganesan, S., Park, B. H., Vahdat, L. T., Leyland-Jones, B. & 6 othersMughal, T. I., Pusztai, L., O'Shaughnessy, J., Miller, V. A., Ross, J. S. & Ali, S. M., Jan 1 2017, In : Annals of Oncology. 28, 11, p. 2866-2873 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
DNA
Neoplasms
Mutation
6 Citations (Scopus)
Genome
Neoplasms
Mutation
Cataloging
Precision Medicine
5 Citations (Scopus)

Nuclear topology modulates the mutational landscapes of cancer genomes

Smith, K. S., Liu, L. L., Ganesan, S., Michor, F. & De, S., Nov 1 2017, In : Nature Structural and Molecular Biology. 24, 11, p. 1000-1006 7 p.

Research output: Contribution to journalArticle

Genome
DNA Repair
DNA Damage
Chromatin
Neoplasms
11 Citations (Scopus)

Patient-derived xenograft models of non-small cell lung cancer and their potential utility in personalized medicine

Morgan, K. M., Riedlinger, G. M., Rosenfeld, J., Ganesan, S. & Pine, S., Jan 19 2017, In : Frontiers in Oncology. 7, JAN, 2.

Research output: Contribution to journalArticle

Precision Medicine
Heterografts
Non-Small Cell Lung Carcinoma
Neoplasms
Therapeutics
2 Citations (Scopus)

Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage

Ginjala, V., Rodriguez-Colon, L., Ganguly, B., Gangidi, P., Gallina, P., Al-Hraishawi, H., Kulkarni, A., Tang, J., Gheeya, J., Simhadri, S., Yao, M., Xia, B. & Ganesan, S., Dec 1 2017, In : Scientific reports. 7, 1, 16613.

Research output: Contribution to journalArticle

Histone-Lysine N-Methyltransferase
DNA Repair
DNA Damage
DNA Breaks
Genomic Instability
3 Citations (Scopus)

Regulation of spindle integrity and mitotic fidelity by BCCIP

Huhn, S. C., Liu, J., Ye, C., Lu, H., Jiang, X., Feng, X., Ganesan, S., White, E. & Shen, Z., Apr 10 2017, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Spindle Apparatus
Spindle Poles
Centrosome
Microtubules
Chromosomes
2 Citations (Scopus)

Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells

Dolfi, S. C., Medina, D., Kareddula, A., Paratala, B., Rose, A., Dhami, J., Chen, S., Ganesan, S., Mackay, G., Vazquez, A. & Hirshfield, K., Jan 1 2017, In : Oncotarget. 8, 27, p. 44639-44653 15 p.

Research output: Contribution to journalArticle

Riluzole
Breast Neoplasms
Glutamic Acid
Neoplasms
metabotropic glutamate receptor type 1
3 Citations (Scopus)

Roadmap to a comprehensive clinical data warehouse for precision medicine applications in oncology

Foran, D., Chen, W., Chu, H., Sadimin, E., Loh, D., Riedlinger, G., Goodell, L. A., Ganesan, S., Hirshfield, K., Rodriguez-Rust, L. & Dipaola, R. S., Mar 2 2017, In : Cancer Informatics. 16, 1176935117694349.

Research output: Contribution to journalArticle

Precision Medicine
Pathology
Physicians
Neoplasms
Electronic Health Records
1 Citation (Scopus)

Roles of BCCIP deficiency in mammary tumorigenesis

Droz-Rosario, R., Lu, H., Liu, J., Liu, N. A., Ganesan, S., Xia, B., Haffty, B. & Shen, Z., Oct 18 2017, In : Breast Cancer Research. 19, 1

Research output: Contribution to journalArticle

Carcinogenesis
Breast
Breast Neoplasms
Triple Negative Breast Neoplasms
Down-Regulation
9 Citations (Scopus)

Surveillance nanotechnology for multi-organ cancer metastases

Kantamneni, H., Zevon, M., Donzanti, M. J., Zhao, X., Sheng, Y., Barkund, S. R., McCabe, L. H., Banach-Petrosky, W., Higgins, L. M., Ganesan, S., Riman, R., Roth, C., Tan, M. C., Pierce, M., Ganapathy, V. & Moghe, P., Dec 1 2017, In : Nature Biomedical Engineering. 1, 12, p. 993-1003 11 p.

Research output: Contribution to journalArticle

Radio Waves
Nanotechnology
Nanoprobes
Adrenal Glands
Neoplasm Metastasis
5 Citations (Scopus)

Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma

Bjørklund, S. S., Panda, A., Kumar, S., Seiler, M., Robinson, D., Gheeya, J., Yao, M., Alnæs, G. I. G., Toppmeyer, D., Riis, M., Naume, B., Børresen-Dale, A. L., Kristensen, V. N., Ganesan, S. & Bhanot, G., Dec 1 2017, In : Scientific reports. 7, 1, 5568.

Research output: Contribution to journalArticle

Ductal Carcinoma
Exons
Alternative Splicing
Atlases
Neoplasms
2016
3 Citations (Scopus)

A novel role of chromodomain protein CBX8 in DNA damage response

Oza, J., Ganguly, B., Kulkarni, A., Ginjala, V., Yao, M. & Ganesan, S., Oct 28 2016, In : Journal of Biological Chemistry. 291, 44, p. 22881-22893 13 p.

Research output: Contribution to journalArticle

DNA Damage
DNA
DNA Repair
Proteins
Epigenomics
19 Citations (Scopus)

Biomarkers for Immunotherapy: Current Developments and Challenges

Spencer, K. R., Wang, J., Silk, A., Ganesan, S., Kaufman, H. L. & Mehnert, J., Jan 1 2016, In : American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Meeting. 35, p. e493-e503

Research output: Contribution to journalArticle

Immunotherapy
Biomarkers
Tumor Microenvironment
Neoplasms
Tumor-Infiltrating Lymphocytes
18 Citations (Scopus)

Clinical actionability of comprehensive genomic profiling for management of rare or refractory cancers

Hirshfield, K., Tolkunov, D., Zhong, H., Ali, S. M., Stein, M., Murphy, S., Vig, H., Vazquez, A., Glod, J., Moss, R. A., Belyi, V., Chan, C., Chen, S., Goodell, L., Foran, D., Yelensky, R., Palma, N. A., Sun, J. X., Miller, V. A., Stephens, P. J. & 10 othersRoss, J. S., Kaufman, H., Poplin, E., Mehnert, J., Tan, A. R., Bertino, J., Aisner, J., DiPaola, R. S., Rodriguez-Rodriguez, L. & Ganesan, S., Nov 1 2016, In : Oncologist. 21, 11, p. 1315-1325 11 p.

Research output: Contribution to journalArticle

Neoplasms
Histology
Proto-Oncogene Proteins c-akt
Genetic Testing
Receptor Protein-Tyrosine Kinases
46 Citations (Scopus)

Comprehensive genomic profiling identifies a subset of Crizotinib- responsive ALK-rearranged non-small cell lung cancer not detected by fluorescence in situ hybridization

Ali, S. M., Hensing, T., Schrock, A. B., Allen, J., Sanford, E., Gowen, K., Kulkarni, A., He, J., Suh, J. H., Lipson, D., Elvin, J. A., Yelensky, R., Chalmers, Z., Chmielecki, J., Peled, N., Klempner, S. J., Firozvi, K., Frampton, G. M., Molina, J. R., Amenon, S. & 14 othersBrahmer, J. R., MacMahon, H., Nowak, J., Ignatius Ou, S. H., Zauderer, M., Ladanyi, M., Zakowski, M., Fischbach, N., Ross, J. S., Stephens, P. J., Miller, V. A., Wakelee, H., Ganesan, S. & Salgia, R., Jun 1 2016, In : Oncologist. 21, 6, p. 762-770 9 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Non-Small Cell Lung Carcinoma
United States Food and Drug Administration
Standard of Care
crizotinib
85 Citations (Scopus)

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer

Mehnert, J., Panda, A., Zhong, H., Hirshfield, K., Damare, S., Lane, K., Sokol, L., Stein, M., Rodriguez-Rodriquez, L., Kaufman, H. L., Ali, S., Ross, J. S., Pavlick, D. C., Bhanot, G., White, E., DiPaola, R. S., Lovell, A., Cheng, J. & Ganesan, S., Jun 1 2016, In : Journal of Clinical Investigation. 126, 6, p. 2334-2340 7 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Mutation
Programmed Cell Death 1 Receptor
Neoplasms
DNA Polymerase II
23 Citations (Scopus)

Molecular characterization of epithelial ovarian cancer: Implications for diagnosis and treatment

Rojas, V., Hirshfield, K., Ganesan, S. & Rodriguez-Rodriguez, L., Dec 15 2016, In : International journal of molecular sciences. 17, 12, 2113.

Research output: Contribution to journalReview article

Tumors
cancer
tumors
Neoplasms
sequencing

Next-generation sequencing based testing for breast cancer

Ganesan, S. & Hirshfield, K., Jan 1 2016, Molecular Pathology of Breast Cancer. Springer International Publishing, p. 299-328 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Breast Neoplasms
BRCA2 Gene
BRCA1 Gene
Genes
Decision Making
4 Citations (Scopus)

Precision Medicine: Implications for Science and Practice

Ganesan, S., Rodriguez-Rodriguez, L. & DiPaola, R. S., Jan 1 2016, In : Journal of the American College of Surgeons. 223, 3, p. 433-439.e1

Research output: Contribution to journalArticle

Precision Medicine
11 Citations (Scopus)

Use of comprehensive genomic profiling to direct point-of-care management of patients with gynecologic cancers

Rodriguez-Rodriguez, L., Hirshfield, K., Rojas, V., DiPaola, R. S., Gibbon, D., Hellmann, M., Isani, S., Leiser, A., Riedlinger, G. M., Wagreich, A., Ali, S. M., Elvin, J. A., Miller, V. A. & Ganesan, S., Apr 1 2016, In : Gynecologic Oncology. 141, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Neoplasms
Clinical Trials
Physicians
Therapeutics
3 Citations (Scopus)

Yin and yang of 4E-BP1 in cancer

Wang, R., Ganesan, S. & Zheng, X. F. S., Jun 2 2016, In : Cell Cycle. 15, 11, p. 1401-1402 2 p.

Research output: Contribution to journalComment/debate

Yin-Yang
Phosphotransferases
Neoplasms
2015
13 Citations (Scopus)

Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors

Labidi-Galy, S. I., Clauss, A., Ng, V., Duraisamy, S., Elias, K. M., Piao, H. Y., Bilal, E., Davidowitz, R. A., Lu, Y., Badalian-Very, G., Györffy, B., Kang, U. B., Ficarro, S., Ganesan, S., Mills, G. B., Marto, J. A. & Drapkin, R., Jan 15 2015, In : Oncogene. 34, 3, p. 299-309 11 p.

Research output: Contribution to journalArticle

Elafin
Ovarian Neoplasms
Breast Neoplasms
Carcinoma
Survival
3 Citations (Scopus)

Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas

Bjørklund, S. S., Kristensen, V. N., Seiler, M., Kumar, S., Alnæs, G. I. G., Ming, Y., Kerrigan, J., Naume, B., Sachidanandam, R., Bhanot, G., Børresen-Dale, A. L. & Ganesan, S., Jul 17 2015, In : BMC cancer. 15, 1, 524.

Research output: Contribution to journalArticle

Estrogen Receptors
Oxidoreductases
Estrogens
Fatty Acids
Breast Neoplasms
14 Citations (Scopus)

IRF5 is a novel regulator of CXCL13 expression in breast cancer that regulates CXCR5 + B- and T-cell trafficking to tumor-conditioned media

Pimenta, E. M., De, S., Weiss, R., Feng, D., Hall, K., Kilic, S., Bhanot, G., Ganesan, S., Ran, S. & Barnes, B. J., May 28 2015, In : Immunology and Cell Biology. 93, 5, p. 486-499 14 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factors
Conditioned Culture Medium
Breast Neoplasms
T-Lymphocytes
Neoplasms
9 Citations (Scopus)

Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells

Teh, J. L. F., Shah, R., La Cava, S., Dolfi, S. C., Mehta, M. S., Kongara, S., Price, S., Ganesan, S., Reuhl, K., Hirshfield, K., Karantza, V. & Chen, S., May 1 2015, In : Breast Cancer Research and Treatment. 151, 1, p. 57-73 17 p.

Research output: Contribution to journalArticle

Breast
Epithelial Cells
Breast Neoplasms
Cell Line
Glutamic Acid
7 Citations (Scopus)

Response to crizotinib in a patient with MET-mutant papillary renal cell cancer after progression on tivantinib

Stein, M., Hirshfield, K., Zhong, H., Singer, E., Ali, S. M. & Ganesan, S., Feb 1 2015, In : European Urology. 67, 2, p. 353-354 2 p.

Research output: Contribution to journalLetter

Pyrazoles
Quinolines
Drug Substitution
Proto-Oncogene Proteins c-met
Pyridines
23 Citations (Scopus)

Sparse Non-negative Matrix Factorization (SNMF) based color unmixing for breast histopathological image analysis

Xu, J., Xiang, L., Wang, G., Ganesan, S., Feldman, M., Shih, N. NC., Gilmore, H. & Madabhushi, A., Dec 1 2015, In : Computerized Medical Imaging and Graphics. 46, p. 20-29 10 p.

Research output: Contribution to journalArticle

Factorization
Image analysis
Breast
Color
Pathology
37 Citations (Scopus)

The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

Joshi, S., Tolkunov, D., Aviv, H., Hakimi, A. A., Yao, M., Hsieh, J. J., Ganesan, S., Chan, C. & White, E., Dec 1 2015, In : Cell Reports. 13, 9, p. 1895-1908 14 p.

Research output: Contribution to journalArticle

Mitochondria
Oxyphilic Adenoma
Tumors
Carcinogenesis
Autophagy
2014
101 Citations (Scopus)

Automatic detection of invasive ductal carcinoma in whole slide images with convolutional neural networks

Cruz-Roa, A., Basavanhally, A., González, F., Gilmore, H., Feldman, M., Ganesan, S., Shih, N., Tomaszewski, J. & Madabhushi, A., Jan 1 2014, Medical Imaging 2014: Digital Pathology. SPIE, 904103. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9041).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ductal Carcinoma
chutes
cancer
Tissue
Neural networks
19 Citations (Scopus)

ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss

Lozy, F., Cai-McRae, X., Teplova, I., Price, S., Reddy, A., Bhanot, G., Ganesan, S., Vazquez, A. & Karantza, V., Jan 1 2014, In : Autophagy. 10, 4, p. 662-676 15 p.

Research output: Contribution to journalArticle

Autophagy
Carcinogenesis
Breast
Breast Neoplasms
Pharmacology
8 Citations (Scopus)

ERG and CHDI heterogeneity in prostate cancer: Use of confocal microscopy in assessment of microscopic foci

Tereshchenko, I. V., Zhong, H., Chekmareva, M. A., Kane-Goldsmith, N., Santanam, U., Petrosky, W., Stein, M., Ganesan, S., Singer, E., Moore, D., Tischfield, J. & DiPaola, R. S., Nov 1 2014, In : Prostate. 74, 15, p. 1551-1559 9 p.

Research output: Contribution to journalArticle

Confocal Microscopy
Prostatic Neoplasms
Neoplasms
Genetic Heterogeneity
Gene Rearrangement
20 Citations (Scopus)

Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice

Simhadri, S., Peterson, S., Patel, D. S., Huo, Y., Cai, H., Bowman-Colin, C., Miller, S., Ludwig, T., Ganesan, S., Bhaumik, M., Bunting, S., Jasin, M. & Xia, B., Jan 1 2014, In : Journal of Biological Chemistry. 289, 35, p. 24617-24629 13 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Recombinational DNA Repair
Meiosis
Germ Cells
Fertility
79 Citations (Scopus)

Mutational landscape of the essential autophagy gene BECN1 in human cancers

Laddha, S. V., Ganesan, S., Chan, C. & White, E., Jan 1 2014, In : Molecular Cancer Research. 12, 4, p. 485-490 6 p.

Research output: Contribution to journalArticle

Essential Genes
Autophagy
Neoplasms
Breast Neoplasms
Ovarian Neoplasms
1 Citation (Scopus)

Next generation sequencing as an aid to diagnosis and treatment of an unusual pediatric brain cancer

Glod, J., Song, M., Sharma, A., Tyagi, R., Rhodes, R. H., Weissmann, D. J., Roychowdhury, S., Khan, A., Kane, M. P., Hirshfield, K., Ganesan, S., DiPaola, R. S. & Rodriguez-Rodriguez, L., Jan 1 2014, In : Journal of Personalized Medicine. 4, 3, p. 402-411 10 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Pediatrics
Neoplasms
Therapeutics
Pathologists
25 Citations (Scopus)

Triple-negative breast cancer: Molecular subtypes and targeted therapy

Hirshfield, K. & Ganesan, S., Jan 1 2014, In : Current Opinion in Obstetrics and Gynecology. 26, 1, p. 34-40 7 p.

Research output: Contribution to journalReview article

Molecular Targeted Therapy
Triple Negative Breast Neoplasms
Gene Expression
Androgen Antagonists
Neoplasms
2013
53 Citations (Scopus)

Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2 -associated hereditary breast cancer

Huo, Y., Cai, H., Teplova, I., Bowman-Colin, C., Chen, G., Price, S., Barnard, N., Ganesan, S., Karantza, V., White, E. & Xia, B., Aug 1 2013, In : Cancer Discovery. 3, 8, p. 894-907 14 p.

Research output: Contribution to journalArticle

Autophagy
Carcinogenesis
Breast Neoplasms
DNA Damage
Neoplasms