Research Output 1967 2019

2019
1 Citation (Scopus)

25-hydroxyvitamin D and Vitamin D binding protein levels in patients with primary hyperparathyroidism before and after parathyroidectomy

Wang, X., Sheng, Z., Meng, L., Su, C., Trooskin, S. & Shapses, S. A., Jan 1 2019, In : Frontiers in Endocrinology. 10, MAR, 171.

Research output: Contribution to journalArticle

Open Access
Vitamin D-Binding Protein
Parathyroidectomy
Primary Hyperparathyroidism
Parathyroid Hormone
Body Mass Index
Open Access
Cytoplasmic and Nuclear Receptors
Cricetinae
Response Elements
Gene Expression
Liver

Age modulates liver responses to asparaginase-induced amino acid stress in mice

Nikonorova, I. A., Zhu, Q., Signore, C. C., Mirek, E. T., Jonsson, W. O., Kong, B., Guo, G. L., Belden, W. J. & Anthony, T. X. G., Jan 1 2019, In : Journal of Biological Chemistry. 294, 38, p. 12864-13875 1012 p.

Research output: Contribution to journalReview article

Open Access
Asparaginase
Liver
Amino Acids
Genes
Transcriptome

Amplifying mTORC2 signals through AMPK during energetic stress

Jacinto, E., Jun 11 2019, In : Science signaling. 12, 585, eaax5855.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Metabolism
Cell Survival
Intercellular Signaling Peptides and Proteins
Cells
16 Citations (Scopus)

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

Saito, T., Nah, J., Oka, S. I., Mukai, R., Monden, Y., Maejima, Y., Ikeda, Y., Sciarretta, S., Liu, T., Li, H., Baljinnyam, E., Fraidenraich, D., Fritzky, L., Zhai, P., Ichinose, S., Isobe, M., Hsu, C. P., Kundu, M. & Sadoshima, J., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 802-819 18 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Autophagy
Ischemia
Mitochondria
Dynamins
3 Citations (Scopus)

Analysis of an improved Cyanophora paradoxa genome assembly

Price, D. C., Goodenough, U. W., Roth, R., Lee, J. H., Kariyawasam, T., Mutwil, M., Ferrari, C., Facchinelli, F., Ball, S. G., Cenci, U., Chan, C. X., Wagner, N. E., Yoon, H. S., Weber, A. P. M. & Bhattacharya, D., Aug 1 2019, In : DNA research : an international journal for rapid publication of reports on genes and genomes. 26, 4, p. 287-299 13 p.

Research output: Contribution to journalArticle

Open Access
Cyanophora
Viridiplantae
Rhodophyta
Peptidoglycan
Genome

A phase I trial of MK-2206 and hydroxychloroquine in patients with advanced solid tumors

Mehnert, J., Kaveney, A. D., Malhotra, J., Spencer, K., Portal, D., Goodin, S., Tan, A. R., Aisner, J., Moss, R. A., Lin, H., Bertino, J., Gibbon, D., Doyle, L. A., White, E. & Stein, M., Jan 1 2019, (Accepted/In press) In : Cancer chemotherapy and pharmacology.

Research output: Contribution to journalArticle

Hydroxychloroquine
Tumors
Neoplasms
Exanthema
Fatigue

At the Interface of Lifestyle, Behavior, and Circadian Rhythms: Metabolic Implications

Bae, S. A., Fang, M. Z., Rustgi, V., Zarbl, H. & Androulakis, I. P., Aug 28 2019, In : Frontiers in Nutrition. 6, 132.

Research output: Contribution to journalReview article

Open Access
Circadian Rhythm
circadian rhythm
lifestyle
Life Style
Circadian Clocks
7 Citations (Scopus)

Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells

Wang, Y., Xiong, H., Liu, D., Hill, C., Ertay, A., Li, J., Zou, Y., Miller, P., White, E., Downward, J., Goldin, R. D., Yuan, X. & Lu, X., May 4 2019, In : Autophagy. 15, 5, p. 886-899 14 p.

Research output: Contribution to journalArticle

Open Access
Epithelial-Mesenchymal Transition
Autophagy
TNF Receptor-Associated Factor 6
Neoplasms
RNA Interference
5 Citations (Scopus)

Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient kras-driven lung tumorigenesis

Bhatt, V., Khayati, K., Hu, Z. S., Lee, A., Kamran, W., Su, X. & Guo, Y., Feb 1 2019, In : Genes and Development. 33, 3-4, p. 150-165 16 p.

Research output: Contribution to journalArticle

Autophagy
Lipid Metabolism
Carcinogenesis
Lung
Neoplasms

Bile Acid Homeostasis in a Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase Double Knockout Mouse Model

Rizzolo, D., Buckley, K., Kong, B., Zhan, L., Shen, J., Stofan, M., Brinker, A., Goedken, M., Buckley, B. & Guo, G., Jul 1 2019, In : Hepatology. 70, 1, p. 389-402 14 p.

Research output: Contribution to journalArticle

Cholestanetriol 26-Monooxygenase
Cholesterol 7-alpha-Hydroxylase
Bile Acids and Salts
Knockout Mice
Homeostasis
1 Citation (Scopus)

Biochemical diversity of glycosphingolipid biosynthesis as a driver of Coccolithovirus competitive ecology

Nissimov, J. I., Talmy, D., Haramaty, L., Fredricks, H. F., Zelzion, E., Knowles, B., Eren, A. M., Vandzura, R., Laber, C. P., Schieler, B. M., Johns, C. T., More, K. D., Coolen, M. J. L., Follows, M. J., Bhattacharya, D., Van Mooy, B. A. S. & Bidle, K., Jun 1 2019, In : Environmental microbiology. 21, 6, p. 2182-2197 16 p.

Research output: Contribution to journalArticle

serine C-palmitoyltransferase
Serine C-Palmitoyltransferase
glycosphingolipids
Emiliania huxleyi
Glycosphingolipids
tea (beverage)
Microbiota
Polyphenols
Tea
gastrointestinal system
1 Citation (Scopus)

Blockade of RAF and autophagy is the one-two punch to take out Ras

White, E., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 3965-3967 3 p.

Research output: Contribution to journalComment/debate

BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin

Park, J., Zhu, Q., Mirek, E., Na, L., Raduwan, H., Anthony, T. G. & Belden, W. J., Jan 1 2019, In : PloS one. 14, 10, e0223803.

Research output: Contribution to journalArticle

Open Access
Heterochromatin
telomeres
Telomere
heterochromatin
Chromosomes

Both gain and loss of Nampt function promote pressure overload-induced heart failure

Byun, J., Oka, S. I., Imai, N., Huang, C. Y., Ralda, G., Zhai, P., Ikeda, Y., Ikeda, S. & Sadoshima, J., Oct 1 2019, In : American journal of physiology. Heart and circulatory physiology. 317, 4, p. H711-H725

Research output: Contribution to journalArticle

Niacinamide
Transferases
Heart Failure
Pressure
Sirtuin 1
7 Citations (Scopus)

Cardiomyopathy in obesity, insulin resistance and diabetes

Nakamura, M. & Sadoshima, J., Jan 1 2019, In : Journal of Physiology.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Cardiomyopathies
Insulin Resistance
Obesity
Heart Failure

CED-4 CARD domain residues can modulate non-apoptotic neuronal regeneration functions independently from apoptosis

Wang, G., Sun, L., Reina, C. P., Song, I., Gabel, C. V. & Driscoll, M., Dec 1 2019, In : Scientific reports. 9, 1, 13315.

Research output: Contribution to journalArticle

Open Access
Caspases
Regeneration
Apoptosis
Caspase 3
Neurons

Chemoprevention of azoxymethane-induced colon carcinogenesis by delta-tocotrienol

Husain, K., Zhang, A., Shivers, S., Davis-Yadley, A., Coppola, D., Yang, C. & Malafa, M. P., Jun 1 2019, In : Cancer Prevention Research. 12, 6, p. 357-366 10 p.

Research output: Contribution to journalArticle

Azoxymethane
Chemoprevention
Colorectal Neoplasms
Colon
Carcinogenesis

Closed loop bioreactor system for the ex vivo expansion of human T cells

LI, MATTHEW., CHIN, LING. I. N. G. Y. E. E., SHUKOR, SYUKRI., TAMAYO, ALFRED., MAUS, MARCELA. V. & Parekkadan, B., Jan 1 2019, In : Cytotherapy. 21, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

Bioreactors
T-Lymphocytes
Cell Proliferation
Silicones
Cell- and Tissue-Based Therapy

Coexpression of YY1 is required to elaborate the effector functions controlled by PLZF in NKT cells

Darcy, P. W., Jin, K., Osorio, L., Denzin, L. & Sant'Angelo, D., Aug 1 2019, In : Journal of Immunology. 203, 3, p. 627-638 12 p.

Research output: Contribution to journalArticle

Yin-Yang
Natural Killer T-Cells
Zinc Fingers
Leukemia
Transcription Factors

Computational simulation of adapter length-dependent lasso probe capture efficiency

Liu, J., Shukor, S., Li, S., Tamayo, A., Tosi, L., Larman, B., Nanda, V., Olson, W. & Parekkadan, B., May 1 2019, In : Biomolecules. 9, 5, 199.

Research output: Contribution to journalArticle

Open Access
Oligonucleotide Probes
Cloning
Oligonucleotides
Organism Cloning
Genes

Convergence of Cell Pharmacology and Drug Delivery

Aijaz, A., Vaninov, N., Allen, A., Barcia, R. N. & Parekkadan, B., Jan 1 2019, In : Stem Cells Translational Medicine. 8, 9, p. 874-879 6 p.

Research output: Contribution to journalArticle

Open Access
Pharmacology
Pharmacokinetics
Pharmaceutical Preparations
Cell Engineering
Regenerative Medicine
1 Citation (Scopus)

Dchs1-fat4 regulation of osteogenic differentiation in mouse

Crespo-Enriquez, I., Hodgson, T., Zakaria, S., Cadoni, E., Shah, M., Allen, S., Al-Khishali, A., Mao, Y., Yiu, A., Petzold, J., Villagomez-Olea, G., Pitsillides, A. A., Irvine, K. & Francis-West, P., Jul 1 2019, In : Development (Cambridge). 146, 14, dev176776.

Research output: Contribution to journalArticle

Open Access
Osteoblasts
Craniofacial Abnormalities
Phenotype
Mutation

Detection of spacer precursors formed in vivo during primed CRISPR adaptation

Shiriaeva, A. A., Savitskaya, E., Datsenko, K. A., Vvedenskaya, I. O., Fedorova, I., Morozova, N., Metlitskaya, A., Sabantsev, A., Nickels, B. E., Severinov, K. & Semenova, E., Dec 1 2019, In : Nature communications. 10, 1, 4603.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
spacers
deoxyribonucleic acid
DNA
immunity

Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective

Collett-Solberg, P. F., Ambler, G., Backeljauw, P. F., Bidlingmaier, M., Biller, B. M. K., Boguszewski, M. C. S., Cheung, P. T., Choong, C. S. Y., Cohen, L. E., Cohen, P., Dauber, A., Deal, C. L., Gong, C., Hasegawa, Y., Hoffman, A. R., Hofman, P. L., Horikawa, R., Jorge, A. A. L., Juul, A., Kamenický, P. & 15 others, Khadilkar, V., Kopchick, J. J., Kriström, B., Lopes, M. D. L. A., Luo, X., Miller, B. S., Misra, M., Netchine, I., Radovick, S., Ranke, M. B., Rogol, A. D., Rosenfeld, R. G., Saenger, P., Wit, J. M. & Woelfle, J., Jan 1 2019, (Accepted/In press) In : Hormone Research in Paediatrics.

Research output: Contribution to journalReview article

Open Access
Internationality
Genetic Therapy
Growth Hormone
Research
Drug Industry
2 Citations (Scopus)

Dietary sulfur amino acid restriction and the integrated stress response: Mechanistic insights

Jonsson, W. O., Margolies, N. S. & Anthony, T. G., Jun 2019, In : Nutrients. 11, 6, 1349.

Research output: Contribution to journalArticle

Open Access
Sulfur Amino Acids
Activating Transcription Factor 4
sulfur amino acids
stress response
transcription factors

Direct and Indirect Effects of Fibroblast Growth Factor (FGF) 15 and FGF19 on Liver Fibrosis Development

Schumacher, J. D., Kong, B., Wu, J., Rizzolo, D., Armstrong, L. E., Chow, M. D., Goedken, M., Lee, Y-H. & Guo, G., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Fibroblast Growth Factors
Liver Cirrhosis
Bile Acids and Salts
Cholestyramine Resin
5 Citations (Scopus)

Doxorubicin-induced cardiomyopathy associated with inhibition of autophagic degradation process and defects in mitochondrial respiration

Abdullah, C. S., Alam, S., Aishwarya, R., Miriyala, S., Bhuiyan, M. A. N., Panchatcharam, M., Pattillo, C. B., Orr, A. W., Sadoshima, J., Hill, J. A. & Bhuiyan, M. S., Dec 1 2019, In : Scientific reports. 9, 1, 2002.

Research output: Contribution to journalArticle

Cardiomyopathies
Doxorubicin
Respiration
Mitochondrial Dynamics
Autophagy
1 Citation (Scopus)

Dual PPARα/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction

Kalliora, C., Kyriazis, I. D., Oka, S. I., Lieu, M. J., Yue, Y., Area-Gomez, E., Pol, C. J., Tian, Y., Mizushima, W., Chin, A., Scerbo, D., Schulze, P. C., Civelek, M., Sadoshima, J., Madesh, M., Goldberg, I. J. & Drosatos, K., Sep 5 2019, In : JCI Insight. 4, 17, e129556.

Research output: Contribution to journalArticle

Sirtuin 1
Peroxisome Proliferator-Activated Receptors
Leptin Receptors
High Fat Diet
Organelle Biogenesis

Dual Roles of Mammalian Target of Rapamycin in Regulating Liver Injury and Tumorigenesis in Autophagy-Defective Mouse Liver

Ni, H. M., Chao, X., Yang, H., Deng, F., Wang, S., Bai, Q., Qian, H., Cui, Y., Cui, W., Shi, Y., Zong, W. X., Wang, Z., Yang, L. & Ding, W. X., Jan 1 2019, In : Hepatology.

Research output: Contribution to journalArticle

Autophagy
Sirolimus
Carcinogenesis
Knockout Mice
Raptors
1 Citation (Scopus)

Early girl is a novel component of the Fat signaling pathway

Misra, J. R. & Irvine, K., Jan 1 2019, In : PLoS genetics. 15, 1, e1007955.

Research output: Contribution to journalArticle

Open Access
fat
Fats
membrane
lipids
Membranes
1 Citation (Scopus)

Effects and mechanisms of tea regulating blood pressure: Evidences and promises

Li, D., Wang, R., Huang, J., Cai, Q., Yang, C. S., Wan, X. & Xie, Z., May 2019, In : Nutrients. 11, 5, 1115.

Research output: Contribution to journalReview article

Open Access
Tea
tea
blood pressure
hypertension
Blood Pressure
1 Citation (Scopus)

Effects of antibiotics on degradation and bioavailability of different vitamin E forms in mice

Ran, L., Liu, A. B., Lee, M. J., Xie, P., Lin, Y. & Yang, C. S., May 1 2019, In : BioFactors. 45, 3, p. 450-462 13 p.

Research output: Contribution to journalArticle

Vitamin E
Biological Availability
Anti-Bacterial Agents
Degradation
Liver
1 Citation (Scopus)

Effects of ascorbic acid supplementation on oxidative stress markers in healthy women following a single bout of exercise

Yimcharoen, M., Kittikunnathum, S., Suknikorn, C., Nak-On, W., Yeethong, P., Anthony, T. & Bunpo, P., Jan 21 2019, In : Journal of the International Society of Sports Nutrition. 16, 1, 2.

Research output: Contribution to journalArticle

Ascorbic Acid
exercise
Oxidative Stress
oxidative stress
ascorbic acid

Effects of intermittent T-cell cluster disaggregation on proliferative capacity and checkpoint marker expression

Li, M., Chin, L. Y., Shukor, S., Tamayo, A. G., Maus, M. V. & Parekkadan, B., Apr 3 2019, In : Autoimmunity. 52, 3, p. 102-107 6 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Translational Medical Research
Cell Size
Immunotherapy
Flow Cytometry
1 Citation (Scopus)

ElemCor: Accurate data analysis and enrichment calculation for high-resolution LC-MS stable isotope labeling experiments

Du, D., Tan, L., Wang, Y., Peng, B., Weinstein, J. N., Wondisford, F., Su, X. & Lorenzi, P. L., Feb 19 2019, In : BMC Bioinformatics. 20, 1, 89.

Research output: Contribution to journalArticle

Isotope Labeling
Isotopes
Labeling
Data analysis
High Resolution

Endocrinology and metabolism

Radovick, S., Aug 1 2019, In : Current Opinion in Pediatrics. 31, 4, 1 p.

Research output: Contribution to journalEditorial

Endocrinology
11 Citations (Scopus)

Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis

Ladinsky, M. S., Araujo, L. P., Zhang, X., Veltri, J., Galan-Diez, M., Soualhi, S., Lee, C., Irie, K., Pinker, E. Y., Narushima, S., Bandyopadhyay, S., Nagayama, M., Elhenawy, W., Coombes, B. K., Ferraris, R. P., Honda, K., Iliev, I. D., Gao, N., Bjorkman, P. J. & Ivanov, I. I., Jan 1 2019, In : Science. 363, 6431, eaat4042.

Research output: Contribution to journalArticle

Endocytosis
Homeostasis
Epithelial Cells
Bacteria
T-Lymphocytes
2 Citations (Scopus)

Endogenous muscle atrophy F-box is involved in the development of cardiac rupture after myocardial infarction

Usui, S., Chikata, A., Takatori, O., Takashima, S. I., Inoue, O., Kato, T., Murai, H., Furusho, H., Nomura, A., Zablocki, D., Kaneko, S., Sadoshima, J. & Takamura, M., Jan 1 2019, In : Journal of Molecular and Cellular Cardiology. 126, p. 1-12 12 p.

Research output: Contribution to journalArticle

Heart Rupture
Muscular Atrophy
Myocardial Infarction
Knockout Mice
Neutrophil Infiltration

Erratum: HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers(J Clin Invest. (2018)128:6(2419–2435) DOI: 10.1172/JCI91814)

Khambu, B., Huda, N., Chen, X., Antoine, D. J., Li, Y., Dai, G., Köhler, U. A., Zong, W. X., Waguri, S., Werner, S., Oury, T. D., Dong, Z. & Yin, X. M., May 1 2019, In : Journal of Clinical Investigation. 129, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
HMGB1 Protein
Autophagy
Mass Spectrometry
Carcinogenesis
Liver
1 Citation (Scopus)

Erratum to: Autophagy maintains tumour growth through circulating arginine (Nature, (2018), 563, 7732, (569-573), 10.1038/s41586-018-0697-7)

Poillet-Perez, L., Xie, X., Zhan, L., Yang, Y., Sharp, D. W., Hu, Z. S., Su, X., Maganti, A., Jiang, C., Lu, W., Zheng, H., Bosenberg, M. W., Mehnert, J., Guo, Y., Lattime, E., Rabinowitz, J. D. & White, E., Jan 3 2019, In : Nature. 565, 7737, p. E3

Research output: Contribution to journalComment/debate

Autophagy
Arginine
Carcinogenesis
Growth
Neoplasms

Evolutionary dynamics of the chromatophore genome in three photosynthetic Paulinella species

Lhee, D., Ha, J. S., Kim, S., Park, M. G., Bhattacharya, D. & Yoon, H. S., Dec 1 2019, In : Scientific reports. 9, 1, 2560.

Research output: Contribution to journalArticle

Open Access
Chromatophores
Plastids
Genome
Genes
Symbiosis

Expansion of phycobilisome linker gene families in mesophilic red algae

Lee, J. M., Kim, D., Bhattacharya, D. & Yoon, H. S., Dec 1 2019, In : Nature communications. 10, 1, 4823.

Research output: Contribution to journalArticle

Open Access
Phycobilisomes
Rhodophyta
algae
Algae
genes
2 Citations (Scopus)

Fast LC-MS quantitation of glucose and glycerol via enzymatic derivatization

Chiles, E., Wang, Y., Kalemba, K. M., Kwon, H., Wondisford, F. & Su, X., Jun 15 2019, In : Analytical Biochemistry. 575, p. 40-43 4 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography
Glycerol
Mass spectrometry
Mass Spectrometry
1 Citation (Scopus)

Flavonoids Alleviating Insulin Resistance through Inhibition of Inflammatory Signaling

Ren, N., Kim, E., Li, B., Pan, H., Tong, T., Yang, C. & Tu, Y., May 15 2019, In : Journal of agricultural and food chemistry. 67, 19, p. 5361-5373 13 p.

Research output: Contribution to journalReview article

Flavonoids
insulin resistance
Insulin Resistance
flavonoids
Insulin
1 Citation (Scopus)

FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury

Kong, B., Zhang, M., Huang, M., Rizzolo, D., Armstrong, L. E., Schumacher, J. D., Chow, M. D., Lee, Y-H. & Guo, G., Apr 1 2019, In : Digestive and Liver Disease. 51, 4, p. 570-576 7 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Alcohols
Liver
Wounds and Injuries
Ethanol
7 Citations (Scopus)

Galectin-3 deficiency ameliorates fibrosis and remodeling in dilated cardiomyopathy mice with enhanced mst1 signaling

Nguyen, M. N., Ziemann, M., Kiriazis, H., Su, Y., Thomas, Z., Lu, Q., Donner, D. G., Zhao, W. B., Rafehi, H., Sadoshima, J., McMullen, J. R., El-Osta, A. & Du, X. J., Jan 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 1, p. H45-H60

Research output: Contribution to journalArticle

Galectin 3
Dilated Cardiomyopathy
Fibrosis
Transgenic Mice
Muscular Diseases

Genetics of Hypopituitarism

Gangat, M. & Radovick, S., Jan 1 2019, Contemporary Endocrinology. Humana Press Inc., p. 29-37 9 p. (Contemporary Endocrinology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypopituitarism
Cell Differentiation
Transcription Factors
Genes
1 Citation (Scopus)

Genome analysis of the rice coral Montipora capitata

Shumaker, A., Putnam, H. M., Qiu, H., Price, D., Zelzion, E., Harel, A., Wagner, N. E., Gates, R. D., Yoon, H. S. & Bhattacharya, D., Dec 1 2019, In : Scientific reports. 9, 1, 2571.

Research output: Contribution to journalArticle

Open Access
Anthozoa
Genome
Cnidaria
Coral Reefs
Dinoflagellida