Research Output 1972 2019

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Review article
2019

Effects and mechanisms of tea regulating blood pressure: Evidences and promises

Li, D., Wang, R., Huang, J., Cai, Q., Yang, C., Wan, X. & Xie, Z., May 1 2019, In : Nutrients. 11, 5, 1115.

Research output: Contribution to journalReview article

Open Access
Tea
tea
blood pressure
hypertension
Blood Pressure

Flavonoids Alleviating Insulin Resistance through Inhibition of Inflammatory Signaling

Ren, N., Kim, E., Li, B., Pan, H., Tong, T., Yang, C. & Tu, Y., May 15 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5361-5373 13 p.

Research output: Contribution to journalReview article

Flavonoids
insulin resistance
Insulin Resistance
flavonoids
Insulin

Genome Evolution of Coral Reef Symbionts as Intracellular Residents

González-Pech, R. A., Bhattacharya, D., Ragan, M. A. & Chan, C. X., Jan 1 2019, In : Trends in Ecology and Evolution.

Research output: Contribution to journalReview article

symbiont
symbiosis
symbionts
coral reefs
coral reef

Role of Macrophages in Acute Lung Injury and Chronic Fibrosis Induced by Pulmonary Toxicants

Laskin, D., Malaviya, R. & Laskin, J., Apr 1 2019, In : Toxicological Sciences. 168, 2, p. 287-301 15 p.

Research output: Contribution to journalReview article

Pulmonary Fibrosis
Acute Lung Injury
Macrophages
Pulmonary diseases
Wounds and Injuries

Role of tumor and host autophagy in cancer metabolism

Poillet-Perez, L. & White, E., Jun 1 2019, In : Genes & development. 33, 11-12, p. 610-619 10 p.

Research output: Contribution to journalReview article

Open Access
Autophagy
Neoplasms
Growth
Starvation
Up-Regulation
2018
4 Citations (Scopus)

Biomanufacturing for clinically advanced cell therapies

Aijaz, A., Li, M., Smith, D., Khong, D., Leblon, C., Fenton, O. S., Olabisi, R., Libutti, S., Tischfield, J., Maus, M. V., Deans, R., Barcia, R. N., Anderson, D. G., Ritz, J., Preti, R. & Parekkadan, B., Jun 1 2018, In : Nature Biomedical Engineering. 2, 6, p. 362-376 15 p.

Research output: Contribution to journalReview article

Transplants
T-cells
Antigens
Cell- and Tissue-Based Therapy
T-Cell Antigen Receptor
19 Citations (Scopus)

Mechanisms of physiological and pathological cardiac hypertrophy

Nakamura, M. & Sadoshima, J., Jul 1 2018, In : Nature Reviews Cardiology. 15, 7, p. 387-407 21 p.

Research output: Contribution to journalReview article

Cardiomegaly
Hypertrophy
Cardiac Myocytes
Untranslated RNA
Workload
24 Citations (Scopus)

New insights into the role of mtor signaling in the cardiovascular system

Sciarretta, S., Forte, M., Frati, G. & Sadoshima, J., Feb 2 2018, In : Circulation research. 122, 3, p. 489-505 17 p.

Research output: Contribution to journalReview article

Sirolimus
Cardiovascular System
Heart Failure
Pharmacology
Physiological Phenomena
18 Citations (Scopus)

Studies on prevention of obesity, metabolic syndrome, diabetes, cardiovascular diseases and cancer by tea

Yang, C., Wang, H. & Sheridan, Z. P., Jan 1 2018, In : Journal of Food and Drug Analysis. 26, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

metabolic syndrome
Tea
tea
cardiovascular diseases
diabetes
12 Citations (Scopus)

The hippo signaling network and its biological functions

Misra, J. R. & Irvine, K., Nov 23 2018, In : Annual Review of Genetics. 52, p. 65-87 23 p.

Research output: Contribution to journalReview article

Cues
Long-Acting Thyroid Stimulator
Cell Proliferation
Cell Polarity
Intercellular Junctions
28 Citations (Scopus)

The Role of Autophagy in the Heart

Sciarretta, S., Maejima, Y., Zablocki, D. & Sadoshima, J., Feb 10 2018, In : Annual Review of Physiology. 80, p. 1-26 26 p.

Research output: Contribution to journalReview article

Autophagy
Homeostasis
Mitochondrial Degradation
Mitochondrial Proteins
Reperfusion Injury

The structure and biological function of CREG

Ghobrial, G., Araujo, L., Jinwala, F., Li, S. & Lee, L., Oct 26 2018, In : Frontiers in Cell and Developmental Biology. 6, OCT, 136.

Research output: Contribution to journalReview article

Genes
Developmental Genes
Somatomedin Receptors
Flavin Mononucleotide
Cysteine Proteases

Transcription factors as critical players in melanoma invasiveness, drug resistance, and opportunities for therapeutic drug development

Cohen-Solal, K. A., Kaufman, H. L. & Lasfar, A., Mar 1 2018, In : Pigment Cell and Melanoma Research. 31, 2, p. 241-252 12 p.

Research output: Contribution to journalReview article

Drug Resistance
Melanoma
Transcription Factors
Tumors
Tumor Microenvironment
2017
15 Citations (Scopus)

Anti-TNFα therapy in inflammatory lung diseases

Malaviya, R., Laskin, J. & Laskin, D., Dec 1 2017, In : Pharmacology and Therapeutics. 180, p. 90-98 9 p.

Research output: Contribution to journalReview article

Lung Diseases
Tumor Necrosis Factor-alpha
Pathology
Therapeutics
Pulmonary Fibrosis
110 Citations (Scopus)

Autophagy and Tumor Metabolism

Kimmelman, A. C. & White, E., May 2 2017, In : Cell Metabolism. 25, 5, p. 1037-1043 7 p.

Research output: Contribution to journalReview article

Autophagy
Neoplasms
Pathologic Processes
Growth
Clinical Trials
8 Citations (Scopus)

Biotic Host–Pathogen Interactions As Major Drivers of Plastid Endosymbiosis

Cenci, U., Bhattacharya, D., Weber, A. P. M., Colleoni, C., Subtil, A. & Ball, S. G., Apr 1 2017, In : Trends in Plant Science. 22, 4, p. 316-328 13 p.

Research output: Contribution to journalReview article

cytosol
symbiosis
plastids
Chlamydiales
host-pathogen relationships
5 Citations (Scopus)

Biotic interactions as drivers of algal origin and evolution

Brodie, J., Ball, S. G., Bouget, F. Y., Chan, C. X., De Clerck, O., Cock, J. M., Gachon, C., Grossman, A. R., Mock, T., Raven, J. A., Saha, M., Smith, A. G., Vardi, A., Yoon, H. S. & Bhattacharya, D., Nov 1 2017, In : The New phytologist. 216, 3, p. 670-681 12 p.

Research output: Contribution to journalReview article

algae
Ecosystem
Coral Reefs
Eutrophication
Knowledge Bases

Cancer Chemoprevention: What Have we Learned?

Yang, C., Wang, H., Dan, V. & Filippo, S. S., Dec 1 2017, In : Current Pharmacology Reports. 3, 6, p. 409-422 14 p.

Research output: Contribution to journalReview article

Chemoprevention
Tamoxifen
Aspirin
Neoplasms
Beverages
20 Citations (Scopus)

Contribution of type III interferons to antiviral immunity: Location, location, location

Kotenko, S. & Durbin, J., May 5 2017, In : Journal of Biological Chemistry. 292, 18, p. 7295-7303 9 p.

Research output: Contribution to journalReview article

Interferon Type I
Adaptive Immunity
Virus Diseases
Viruses
Innate Immunity
7 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Metabolomics
Cardiomegaly
Epigenomics
Heart Failure
18 Citations (Scopus)

SERPINB3 and B4: From biochemistry to biology

Sun, Y., Sheshadri, N. & Zong, W-X., Feb 1 2017, In : Seminars in Cell and Developmental Biology. 62, p. 170-177 8 p.

Research output: Contribution to journalReview article

Biochemistry
Cysteine Proteinase Inhibitors
Serine Proteinase Inhibitors
Gene Duplication
Substrate Specificity
12 Citations (Scopus)

The Algal Revolution

Brodie, J., Chan, C. X., De Clerck, O., Cock, J. M., Coelho, S. M., Gachon, C., Grossman, A. R., Mock, T., Raven, J. A., Smith, A. G., Yoon, H. S. & Bhattacharya, D., Aug 1 2017, In : Trends in Plant Science. 22, 8, p. 726-738 13 p.

Research output: Contribution to journalReview article

algae
biofuels
functional foods
eukaryotic cells
phenotype

Unexpected functional consequences of the loss of the autophagy-related conjugation system

Saito, T. & Sadoshima, J., Feb 17 2017, In : Circulation research. 120, 4, p. 610-612 3 p.

Research output: Contribution to journalReview article

Autophagy
Autophagosomes
2016
80 Citations (Scopus)

Aging and Autophagy in the Heart

Shirakabe, A., Ikeda, Y., Sciarretta, S., Zablocki, D. K. & Sadoshima, J., May 13 2016, In : Circulation research. 118, 10, p. 1563-1576 14 p.

Research output: Contribution to journalReview article

Autophagy
Proteins
Organelles
Mitochondria
Caloric Restriction
34 Citations (Scopus)

Cancer Prevention: Obstacles, Challenges, and the Road Ahead

Meyskens, F. L., Mukhtar, H., Rock, C. L., Cuzick, J., Kensler, T. W., Yang, C., Ramsey, S. D., Lippman, S. M. & Alberts, D. S., Feb 1 2016, In : Journal of the National Cancer Institute. 108, 2, djv309.

Research output: Contribution to journalReview article

Neoplasms
Comparative Effectiveness Research
Genetic Heterogeneity
Health Services Needs and Demand
Colorectal Neoplasms
43 Citations (Scopus)

Cancer preventive activities of tea catechins

Yang, C. & Wang, H., Dec 1 2016, In : Molecules. 21, 12, 1679.

Research output: Contribution to journalReview article

Catechin
Tea
cancer
Neoplasms
gallates
25 Citations (Scopus)

Fatty liver diseases, bile acids, and FXR

Zhu, Y., Liu, H., Zhang, M. & Guo, G., Sep 1 2016, In : Acta Pharmaceutica Sinica B. 6, 5, p. 409-412 4 p.

Research output: Contribution to journalReview article

Fatty Liver
Bile Acids and Salts
Liver Diseases
Homeostasis
Fibrosis
8 Citations (Scopus)

Heterogeneity in oligodendroglia: Is it relevant to mouse models and human disease?

Ornelas, I. M., McLane, L. E., Saliu, A., Evangelou, A. V., Khandker, L. & Wood, T., Dec 1 2016, In : Journal of Neuroscience Research. 94, 12, p. 1421-1433 13 p.

Research output: Contribution to journalReview article

Oligodendroglia
Central Nervous System
Demyelinating Diseases
Knockout Mice
Transgenic Mice
9 Citations (Scopus)

IFN-λ cancer immunotherapy: New kid on the block

Lasfar, A., Gogas, H., Zloza, A., Kaufman, H. L. & Kirkwood, J. M., Jul 1 2016, In : Immunotherapy. 8, 8, p. 877-888 12 p.

Research output: Contribution to journalReview article

Immunotherapy
Interferons
Neoplasms
Adaptive Immunity
Innate Immunity
9 Citations (Scopus)

Lessons learned from cancer prevention studies with nutrients and non-nutritive dietary constituents

Yang, C., Chen, J. X., Wang, H. & Lim, J., Jun 1 2016, In : Molecular nutrition & food research. 60, 6, p. 1239-1250 12 p.

Research output: Contribution to journalReview article

Food
neoplasms
nutrients
Neoplasms
Food and Beverages
3 Citations (Scopus)

Macrophages and inflammatory mediators in pulmonary injury induced by mustard vesicants

Malaviya, R., Sunil, V. R., Venosa, A., Vayas, K. N., Businaro, R., Heck, D. E., Laskin, J. & Laskin, D., Jan 1 2016, In : Annals of the New York Academy of Sciences. 1374, 1, p. 168-175 8 p.

Research output: Contribution to journalReview article

Mustard Gas
Mechlorethamine
Mustard Plant
Irritants
Macrophages
96 Citations (Scopus)

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea

Yang, C., Zhang, J., Zhang, L., Huang, J. & Wang, Y., Jan 1 2016, In : Molecular Nutrition and Food Research. 60, 1, p. 160-174 15 p.

Research output: Contribution to journalReview article

tea (beverage)
metabolic syndrome
Tea
Weight Loss
weight loss
185 Citations (Scopus)

Mitochondria and Cancer

Zong, W-X., Rabinowitz, J. D. & White, E., Mar 3 2016, In : Molecular cell. 61, 5, p. 667-676 10 p.

Research output: Contribution to journalReview article

Mitochondria
Neoplasms
Mitochondrial Genome
Mutation
Citric Acid Cycle
15 Citations (Scopus)

Mitochondrial autophagy in cardiomyopathy

Tong, M. & Sadoshima, J., Jun 1 2016, In : Current Opinion in Genetics and Development. 38, p. 8-15 8 p.

Research output: Contribution to journalReview article

Autophagy
Cardiomyopathies
Cardiac Myocytes
Mitochondrial Degradation
Mitochondrial Dynamics
13 Citations (Scopus)

Mustard vesicant-induced lung injury: Advances in therapy

Weinberger, B., Malaviya, R., Sunil, V. R., Venosa, A., Heck, D. E., Laskin, J. & Laskin, D., Aug 15 2016, In : Toxicology and Applied Pharmacology. 305, p. 1-11 11 p.

Research output: Contribution to journalReview article

Mustard Plant
Irritants
Lung Injury
Toxicity
Acetylcysteine
121 Citations (Scopus)

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

Birge, R., Boeltz, S., Kumar, S., Carlson, J., Wanderley, J., Calianese, D., Barcinski, M., Brekken, R. A., Huang, X., Hutchins, J. T., Freimark, B., Empig, C., Mercer, J., Schroit, A. J., Schett, G. & Herrmann, M., Jun 1 2016, In : Cell Death and Differentiation. 23, 6, p. 962-978 17 p.

Research output: Contribution to journalReview article

Phosphatidylserines
Immunosuppressive Agents
Communicable Diseases
Neoplasms
Infection
119 Citations (Scopus)

Recent insights into the function of autophagy in cancer

Amaravadi, R., Kimmelman, A. C. & White, E., Sep 1 2016, In : Genes and Development. 30, 17, p. 1913-1930 18 p.

Research output: Contribution to journalReview article

Autophagy
Neoplasms
Organelles
Food
Cell Aging
2015
20 Citations (Scopus)

Compartmentalizing intestinal epithelial cell toll-like receptors for immune surveillance

Yu, S. & Gao, N., Sep 12 2015, In : Cellular and Molecular Life Sciences. 72, 17, p. 3343-3353 11 p.

Research output: Contribution to journalReview article

Toll-Like Receptors
Epithelial Cells
Inflammatory Bowel Diseases
Dendritic Cells
Cell Biology
419 Citations (Scopus)

Essential versus accessory aspects of cell death: Recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., Baehrecke, E. H., Bazan, N. G., Bertrand, M. J., Bianchi, K., Blagosklonny, M. V., Blomgren, K., Borner, C., Bredesen, D. E., Brenner, C., Campanella, M. & 88 othersCandi, E., Cecconi, F., Chan, F. K., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Di Daniele, N., Dixit, V. M., Dynlacht, B. D., El-Deiry, W. S., Fimia, G. M., Flavell, R. A., Fulda, S., Garrido, C., Gougeon, M. L., Green, D. R., Gronemeyer, H., Hajnoczky, G., Hardwick, J. M., Hengartner, M. O., Ichijo, H., Joseph, B., Jost, P. J., Kaufmann, T., Kepp, O., Klionsky, D. J., Knight, R. A., Kumar, S., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lugli, E., Madeo, F., Malorni, W., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Meier, P., Melino, S., Mizushima, N., Moll, U., Muñoz-Pinedo, C., Nuñez, G., Oberst, A., Panaretakis, T., Penninger, J. M., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H., Puthalakath, H., Rabinovich, G. A., Ravichandran, K. S., Rizzuto, R., Rodrigues, C. M., Rubinsztein, D. C., Rudel, T., Shi, Y., Simon, H. U., Stockwell, B. R., Szabadkai, G., Tait, S. W., Tang, H. L., Tavernarakis, N., Tsujimoto, Y., Vanden Berghe, T., Vandenabeele, P., Villunger, A., Wagner, E. F., Walczak, H., White, E., Wood, W. G., Yuan, J., Zakeri, Z., Zhivotovsky, B., Melino, G. & Kroemer, G., Jan 1 2015, In : Cell Death and Differentiation. 22, 1, p. 58-73 16 p.

Research output: Contribution to journalReview article

Cell Death
Biochemical Phenomena
Genetic Engineering
Cytoprotection
Caspases
30 Citations (Scopus)

Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration

Li, G. & Guo, G., Jan 1 2015, In : Acta Pharmaceutica Sinica B. 5, 2, p. 93-98 6 p.

Research output: Contribution to journalReview article

Liver Regeneration
Cytoplasmic and Nuclear Receptors
Bile Acids and Salts
Hepatectomy
Ligands
4 Citations (Scopus)

Homeostatic responses to amino acid insufficiency

Anthony, T., Sep 1 2015, In : Animal Nutrition. 1, 3, p. 135-137 3 p.

Research output: Contribution to journalReview article

stress response
Amino Acids
amino acids
Health
mechanistic target of rapamycin complex 1
46 Citations (Scopus)

Insulin and IGF receptor signalling in neural-stem-cell homeostasis

Ziegler, A. N., Levison, S. & Wood, T., Mar 26 2015, In : Nature Reviews Endocrinology. 11, 3, p. 161-170 10 p.

Research output: Contribution to journalReview article

Somatomedin Receptors
Neural Stem Cells
Homeostasis
Insulin
Insulin-Like Growth Factor II
19 Citations (Scopus)

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression

Nahta, R., Al-Mulla, F., Al-Temaimi, R., Amedei, A., Andrade-Vieira, R., Bay, S., Brown, D. G., Calaf, G. M., Castellino, R. C., Cohen-Solal, K. A., Colacci, A., Cruickshanks, N., Dent, P., Di Fiore, R., Forte, S., Goldberg, G. S., Hamid, R. A., Krishnan, H., Laird, D. W., Lasfar, A. & 18 othersMarignani, P. A., Memeo, L., Mondello, C., Naus, C. C., Ponce-Cusi, R., Raju, J., Roy, D., Roy, R., Ryan, E. P., Salem, H. K., Ivana Scovassi, A., Singh, N., Vaccari, M., Vento, R., Vondráček, J., Wade, M., Woodrick, J. & Bisson, W. H., Jun 1 2015, In : Carcinogenesis. 36, p. S2-S18

Research output: Contribution to journalReview article

Growth
Contact Inhibition
Neoplasms
Retinoblastoma Protein
Gap Junctions
31 Citations (Scopus)

Mechanistic review of drug-induced steatohepatitis

Schumacher, J. D. & Guo, G., Jun 18 2015, In : Toxicology and Applied Pharmacology. 289, 1, p. 40-47 8 p.

Research output: Contribution to journalReview article

Fatty Liver
Pharmaceutical Preparations
Type I DNA Topoisomerase
Mitochondria
Chemotherapy
51 Citations (Scopus)

Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular system

Ikeda, Y., Shirakabe, A., Brady, C., Zablocki, D., Ohishi, M. & Sadoshima, J., Jan 1 2015, In : Journal of Molecular and Cellular Cardiology. 78, p. 116-122 7 p.

Research output: Contribution to journalReview article

Mitochondrial Degradation
Mitochondrial Dynamics
Cardiovascular System
Mitochondria
Organelles
78 Citations (Scopus)

Molecular mechanisms of mitochondrial autophagy/mitophagy in the heart

Saito, T. & Sadoshima, J., Apr 10 2015, In : Circulation research. 116, 8, p. 1477-1490 14 p.

Research output: Contribution to journalReview article

Mitochondrial Degradation
Autophagy
Yeasts
Uncertainty
Mammals
52 Citations (Scopus)

RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression

Cohen-Solal, K. A., Boregowda, R. K. & Lasfar, A., Jul 25 2015, In : Molecular Cancer. 14, 1, 137.

Research output: Contribution to journalReview article

Phosphatidylinositol 3-Kinases
Neoplasms
Neoplasm Metastasis
Critical Pathways
Osteosarcoma
88 Citations (Scopus)

The role of sirtuins in cardiac disease

Matsushima, S. & Sadoshima, J., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 9, p. H1375-H1389

Research output: Contribution to journalReview article

Sirtuins
Heart Diseases
Histone Deacetylases
Cardiomegaly
Histone Code
2014
29 Citations (Scopus)

Applications of next-generation sequencing to unravelling the evolutionary history of algae

Kim, K. M., Park, J. H., Bhattacharya, D. & Yoon, H. S., Feb 11 2014, In : International Journal of Systematic and Evolutionary Microbiology. 64, PART 2, p. 333-345 13 p.

Research output: Contribution to journalReview article

algae
Symbiosis
genome
History
alga
270 Citations (Scopus)

Consensus guidelines for the detection of immunogenic cell death

Kepp, O., Senovilla, L., Vitale, I., Vacchelli, E., Adjemian, S., Agostinis, P., Apetoh, L., Aranda, F., Barnaba, V., Bloy, N., Bracci, L., Breckpot, K., Brough, D., Buqué, A., Castro, M. G., Cirone, M., Colombo, M. I., Cremer, I., Demaria, S., Dini, L. & 62 othersEliopoulos, A. G., Faggioni, A., Formenti, S. C., Fučíková, J., Gabriele, L., Gaipl, U. S., Galon, J., Garg, A., Ghiringhelli, F., Giese, N. A., Guo, Z. S., Hemminki, A., Herrmann, M., Hodge, J. W., Holdenrieder, S., Honeychurch, J., Hu, H. M., Huang, X., Illidge, T. M., Kono, K., Korbelik, M., Krysko, D. V., Loi, S., Lowenstein, P. R., Lugli, E., Ma, Y., Madeo, F., Manfredi, A. A., Martins, I., Mavilio, D., Menger, L., Merendino, N., Michaud, M., Mignot, G., Mossman, K. L., Multhoff, G., Oehler, R., Palombo, F., Panaretakis, T., Pol, J., Proietti, E., Ricci, J. E., Riganti, C., Rovere-Querini, P., Rubartelli, A., Sistigu, A., Smyth, M. J., Sonnemann, J., Spisek, R., Stagg, J., Sukkurwala, A. Q., Tartour, E., Thorburn, A., Thorne, S. H., Vandenabeele, P., Velotti, F., Workenhe, S. T., Yang, H., Zong, W-X., Zitvogel, L., Kroemer, G. & Galluzzi, L., Oct 1 2014, In : OncoImmunology. 3, 9, e955691.

Research output: Contribution to journalReview article

Cell Death
Guidelines
Immune System
Small Molecule Libraries
Calreticulin