Research Output 1972 2019

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Review article
2016
11 Citations (Scopus)

IFN-lambda therapy: Current status and future perspectives

Lasfar, A., Zloza, A. & Cohen-Solal, K. A., Jan 1 2016, In : Drug Discovery Today. 21, 1, p. 167-171 5 p.

Research output: Contribution to journalReview article

Interferons
Virus Diseases
Therapeutics
Chronic Hepatitis C
Innate Immunity
10 Citations (Scopus)

IFN-λ: A new inducer of local immunity against cancer and infections

Lasfar, A., Zloza, A., de la Torre, A. & Cohen-Solal, K. A., Jan 1 2016, In : Frontiers in immunology. 7, DEC, 598.

Research output: Contribution to journalReview article

Immunity
Infection
Innate Immunity
Autoimmune Diseases
Gastrointestinal Tract
10 Citations (Scopus)

IFN-λ cancer immunotherapy: New kid on the block

Lasfar, A., Gogas, H., Zloza, A., Kaufman, H. L. & Kirkwood, J. M., Jul 1 2016, In : Immunotherapy. 8, 8, p. 877-888 12 p.

Research output: Contribution to journalReview article

Immunotherapy
Interferons
Neoplasms
Adaptive Immunity
Innate Immunity
9 Citations (Scopus)

Lessons learned from cancer prevention studies with nutrients and non-nutritive dietary constituents

Yang, C., Chen, J. X., Wang, H. & Lim, J., Jun 1 2016, In : Molecular nutrition & food research. 60, 6, p. 1239-1250 12 p.

Research output: Contribution to journalReview article

Food
neoplasms
nutrients
Neoplasms
Food and Beverages
4 Citations (Scopus)

Macrophages and inflammatory mediators in pulmonary injury induced by mustard vesicants

Malaviya, R., Sunil, V. R., Venosa, A., Vayas, K. N., Businaro, R., Heck, D. E., Laskin, J. D. & Laskin, D. L., Jan 1 2016, In : Annals of the New York Academy of Sciences. 1374, 1, p. 168-175 8 p.

Research output: Contribution to journalReview article

Mustard Gas
Mechlorethamine
Mustard Plant
Irritants
Macrophages
104 Citations (Scopus)

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea

Yang, C., Zhang, J., Zhang, L., Huang, J. & Wang, Y., Jan 1 2016, In : Molecular Nutrition and Food Research. 60, 1, p. 160-174 15 p.

Research output: Contribution to journalReview article

tea (beverage)
metabolic syndrome
Tea
Weight Loss
weight loss
4 Citations (Scopus)

Mechanisms of protein balance in skeletal muscle

Anthony, T., Jan 1 2016, In : Domestic Animal Endocrinology. 56, p. S23-S32

Research output: Contribution to journalReview article

skeletal muscle
Skeletal Muscle
homeostasis
Proteins
proteins
221 Citations (Scopus)

Mitochondria and Cancer

Zong, W. X., Rabinowitz, J. D. & White, E., Mar 3 2016, In : Molecular cell. 61, 5, p. 667-676 10 p.

Research output: Contribution to journalReview article

Mitochondria
Neoplasms
Mitochondrial Genome
Mutation
Citric Acid Cycle
20 Citations (Scopus)

Mitochondrial autophagy in cardiomyopathy

Tong, M. & Sadoshima, J., Jun 1 2016, In : Current Opinion in Genetics and Development. 38, p. 8-15 8 p.

Research output: Contribution to journalReview article

Autophagy
Cardiomyopathies
Cardiac Myocytes
Mitochondrial Degradation
Mitochondrial Dynamics
14 Citations (Scopus)

Mustard vesicant-induced lung injury: Advances in therapy

Weinberger, B., Malaviya, R., Sunil, V. R., Venosa, A., Heck, D. E., Laskin, J. D. & Laskin, D. L., Aug 15 2016, In : Toxicology and Applied Pharmacology. 305, p. 1-11 11 p.

Research output: Contribution to journalReview article

Mustard Plant
Irritants
Lung Injury
Toxicity
Acetylcysteine
138 Citations (Scopus)

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

Birge, R., Boeltz, S., Kumar, S., Carlson, J., Wanderley, J., Calianese, D., Barcinski, M., Brekken, R. A., Huang, X., Hutchins, J. T., Freimark, B., Empig, C., Mercer, J., Schroit, A. J., Schett, G. & Herrmann, M., Jun 1 2016, In : Cell Death and Differentiation. 23, 6, p. 962-978 17 p.

Research output: Contribution to journalReview article

Phosphatidylserines
Immunosuppressive Agents
Communicable Diseases
Neoplasms
Infection
157 Citations (Scopus)

Recent insights into the function of autophagy in cancer

Amaravadi, R., Kimmelman, A. C. & White, E., Sep 1 2016, In : Genes and Development. 30, 17, p. 1913-1930 18 p.

Research output: Contribution to journalReview article

Autophagy
Neoplasms
Organelles
Food
Cell Aging
14 Citations (Scopus)

Regulation of Hepatic Stellate Cells and Fibrogenesis by Fibroblast Growth Factors

Schumacher, J. D. & Guo, G., Jan 1 2016, In : BioMed Research International. 2016, 8323747.

Research output: Contribution to journalReview article

Hepatic Stellate Cells
Fibroblast Growth Factors
Cell proliferation
Liver
Hepatocytes
3 Citations (Scopus)

Using measures of single-cell physiology and physiological state to understand organismic aging

Mendenhall, A., Driscoll, M. & Brent, R., Feb 1 2016, In : Aging cell. 15, 1, p. 4-13 10 p.

Research output: Contribution to journalReview article

Cell Physiological Phenomena
Chromatin
DNA
DNA Methylation
Reporter Genes
2015
190 Citations (Scopus)

Autophagy, Metabolism, and Cancer

White, E., Mehnert, J. M. & Chan, C. S., Nov 15 2015, In : Clinical Cancer Research. 21, 22, p. 5037-5046 10 p.

Research output: Contribution to journalReview article

Autophagy
Neoplasms
Starvation
Organelles
Recycling
24 Citations (Scopus)

Compartmentalizing intestinal epithelial cell toll-like receptors for immune surveillance

Yu, S. & Gao, N., Sep 12 2015, In : Cellular and Molecular Life Sciences. 72, 17, p. 3343-3353 11 p.

Research output: Contribution to journalReview article

Toll-Like Receptors
Epithelial Cells
Inflammatory Bowel Diseases
Dendritic Cells
Cell Biology
453 Citations (Scopus)

Essential versus accessory aspects of cell death: Recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., Baehrecke, E. H., Bazan, N. G., Bertrand, M. J., Bianchi, K., Blagosklonny, M. V., Blomgren, K., Borner, C., Bredesen, D. E., Brenner, C., Campanella, M. & 88 others, Candi, E., Cecconi, F., Chan, F. K., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Di Daniele, N., Dixit, V. M., Dynlacht, B. D., El-Deiry, W. S., Fimia, G. M., Flavell, R. A., Fulda, S., Garrido, C., Gougeon, M. L., Green, D. R., Gronemeyer, H., Hajnoczky, G., Hardwick, J. M., Hengartner, M. O., Ichijo, H., Joseph, B., Jost, P. J., Kaufmann, T., Kepp, O., Klionsky, D. J., Knight, R. A., Kumar, S., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lugli, E., Madeo, F., Malorni, W., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Meier, P., Melino, S., Mizushima, N., Moll, U., Muñoz-Pinedo, C., Nuñez, G., Oberst, A., Panaretakis, T., Penninger, J. M., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H., Puthalakath, H., Rabinovich, G. A., Ravichandran, K. S., Rizzuto, R., Rodrigues, C. M., Rubinsztein, D. C., Rudel, T., Shi, Y., Simon, H. U., Stockwell, B. R., Szabadkai, G., Tait, S. W., Tang, H. L., Tavernarakis, N., Tsujimoto, Y., Vanden Berghe, T., Vandenabeele, P., Villunger, A., Wagner, E. F., Walczak, H., White, E., Wood, W. G., Yuan, J., Zakeri, Z., Zhivotovsky, B., Melino, G. & Kroemer, G., Jan 1 2015, In : Cell Death and Differentiation. 22, 1, p. 58-73 16 p.

Research output: Contribution to journalReview article

Cell Death
Biochemical Phenomena
Genetic Engineering
Cytoprotection
Caspases
31 Citations (Scopus)

Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration

Li, G. & Guo, G., Jan 1 2015, In : Acta Pharmaceutica Sinica B. 5, 2, p. 93-98 6 p.

Research output: Contribution to journalReview article

Liver Regeneration
Cytoplasmic and Nuclear Receptors
Bile Acids and Salts
Hepatectomy
Ligands
4 Citations (Scopus)

Homeostatic responses to amino acid insufficiency

Anthony, T., Sep 1 2015, In : Animal Nutrition. 1, 3, p. 135-137 3 p.

Research output: Contribution to journalReview article

stress response
Amino Acids
amino acids
Health
mechanistic target of rapamycin complex 1
4 Citations (Scopus)
Xenobiotics
Carcinogenesis
Herb-Drug Interactions
Carcinogens
Pharmaceutical Preparations
51 Citations (Scopus)

Insulin and IGF receptor signalling in neural-stem-cell homeostasis

Ziegler, A. N., Levison, S. & Wood, T., Mar 26 2015, In : Nature Reviews Endocrinology. 11, 3, p. 161-170 10 p.

Research output: Contribution to journalReview article

Somatomedin Receptors
Neural Stem Cells
Homeostasis
Insulin
Insulin-Like Growth Factor II
19 Citations (Scopus)

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression

Nahta, R., Al-Mulla, F., Al-Temaimi, R., Amedei, A., Andrade-Vieira, R., Bay, S., Brown, D. G., Calaf, G. M., Castellino, R. C., Cohen-Solal, K. A., Colacci, A., Cruickshanks, N., Dent, P., Di Fiore, R., Forte, S., Goldberg, G. S., Hamid, R. A., Krishnan, H., Laird, D. W., Lasfar, A. & 18 others, Marignani, P. A., Memeo, L., Mondello, C., Naus, C. C., Ponce-Cusi, R., Raju, J., Roy, D., Roy, R., Ryan, E. P., Salem, H. K., Ivana Scovassi, A., Singh, N., Vaccari, M., Vento, R., Vondráček, J., Wade, M., Woodrick, J. & Bisson, W. H., Jun 1 2015, In : Carcinogenesis. 36, p. S2-S18

Research output: Contribution to journalReview article

Growth
Contact Inhibition
Neoplasms
Retinoblastoma Protein
Gap Junctions
33 Citations (Scopus)

Mechanistic review of drug-induced steatohepatitis

Schumacher, J. D. & Guo, G., Jun 18 2015, In : Toxicology and Applied Pharmacology. 289, 1, p. 40-47 8 p.

Research output: Contribution to journalReview article

Fatty Liver
Pharmaceutical Preparations
Type I DNA Topoisomerase
Mitochondria
Chemotherapy
56 Citations (Scopus)

Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular system

Ikeda, Y., Shirakabe, A., Brady, C., Zablocki, D., Ohishi, M. & Sadoshima, J., Jan 1 2015, In : Journal of Molecular and Cellular Cardiology. 78, p. 116-122 7 p.

Research output: Contribution to journalReview article

Mitochondrial Degradation
Mitochondrial Dynamics
Cardiovascular System
Mitochondria
Organelles
92 Citations (Scopus)

Molecular mechanisms of mitochondrial autophagy/mitophagy in the heart

Saito, T. & Sadoshima, J., Apr 10 2015, In : Circulation research. 116, 8, p. 1477-1490 14 p.

Research output: Contribution to journalReview article

Mitochondrial Degradation
Autophagy
Yeasts
Uncertainty
Mammals
54 Citations (Scopus)

RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression

Cohen-Solal, K. A., Boregowda, R. K. & Lasfar, A., Jul 25 2015, In : Molecular Cancer. 14, 1, 137.

Research output: Contribution to journalReview article

Phosphatidylinositol 3-Kinases
Neoplasms
Neoplasm Metastasis
Critical Pathways
Osteosarcoma
448 Citations (Scopus)

The role for autophagy in cancer

White, E., Jan 2 2015, In : Journal of Clinical Investigation. 125, 1, p. 42-46 5 p.

Research output: Contribution to journalReview article

Autophagy
Neoplasms
Organelles
Carcinogenesis
Waste Products
96 Citations (Scopus)

The role of sirtuins in cardiac disease

Matsushima, S. & Sadoshima, J., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 9, p. H1375-H1389

Research output: Contribution to journalReview article

Sirtuins
Heart Diseases
Histone Deacetylases
Cardiomegaly
Histone Code
2014
30 Citations (Scopus)

Applications of next-generation sequencing to unravelling the evolutionary history of algae

Kim, K. M., Park, J. H., Bhattacharya, D. & Yoon, H. S., Feb 11 2014, In : International Journal of Systematic and Evolutionary Microbiology. 64, PART 2, p. 333-345 13 p.

Research output: Contribution to journalReview article

algae
Symbiosis
genome
History
alga
9 Citations (Scopus)

Chemo/Dietary prevention of cancer: Perspectives in China

Yang, C. S. & Fengb, Q., Jan 1 2014, In : Journal of Biomedical Research. 28, 6, p. 447-455 9 p.

Research output: Contribution to journalReview article

China
Nutrients
Neoplasms
Nutrition
Carcinogens
17 Citations (Scopus)

Crk at the quarter century mark: Perspectives in signaling and cancer

Kumar, S., Fajardo, J. E., Birge, R. B. & Sriram, G., May 2014, In : Journal of Cellular Biochemistry. 115, 5, p. 819-825 7 p.

Research output: Contribution to journalReview article

src Homology Domains
Signal transduction
Neoplasms
Proteins
Signal Transduction
5 Citations (Scopus)

Identifying the assembly pathway of cyanophage inside the marine bacterium using electron cryo-tomography

Dai, W., Schmid, M. F., King, J. A. & Chiu, W., Jan 2014, In : Microbial Cell. 1, 1, p. 45-47 3 p.

Research output: Contribution to journalReview article

Open Access
Electron Microscope Tomography
Bacteriophages
Tomography
Bacteria
Fixatives
15 Citations (Scopus)

Magnesium and embryonic development

Komiya, Y., Su, L. T., Chen, H. C., Habas, R. & Runnels, L. W., Jan 1 2014, In : Magnesium Research. 27, 1, p. 1-8 8 p.

Research output: Contribution to journalReview article

Gastrulation
Ion Channels
Magnesium
Embryonic Development
Neural Crest
177 Citations (Scopus)

Mammalian target of rapamycin signaling in cardiac physiology and disease

Sciarretta, S., Volpe, M. & Sadoshima, J., Jan 31 2014, In : Circulation research. 114, 3, p. 549-564 16 p.

Research output: Contribution to journalReview article

Sirolimus
Heart Diseases
Cardiovascular Physiological Phenomena
Hypertrophy
Genetic Load
50 Citations (Scopus)

New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart

Ikeda, Y., Sciarretta, S., Nagarajan, N., Rubattu, S., Volpe, M., Frati, G. & Sadoshima, J., Jan 1 2014, In : Oxidative medicine and cellular longevity. 2014, 210934.

Research output: Contribution to journalReview article

Mitochondrial Dynamics
Oxidative stress
Autophagy
Oxidative Stress
Aging of materials
16 Citations (Scopus)

Oxidative stress-induced autophagy: Role in pulmonary toxicity

Malaviya, R., Laskin, J. & Laskin, D., Mar 1 2014, In : Toxicology and Applied Pharmacology. 275, 2, p. 145-151 7 p.

Research output: Contribution to journalReview article

Oxidative stress
Autophagy
Toxicity
Oxidative Stress
Lung
45 Citations (Scopus)

Physiological and pathological functions of NADPH oxidases during myocardial ischemia-reperfusion

Matsushima, S., Tsutsui, H. & Sadoshima, J., Jan 1 2014, In : Trends in Cardiovascular Medicine. 24, 5, p. 202-205 4 p.

Research output: Contribution to journalReview article

Myocardial Reperfusion
NADPH Oxidase
Myocardial Ischemia
Reactive Oxygen Species
Reperfusion Injury
70 Citations (Scopus)

Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment

Yue, W., Yang, C. S., DiPaola, R. S. & Tan, X. L., Apr 2014, In : Cancer Prevention Research. 7, 4, p. 388-397 10 p.

Research output: Contribution to journalReview article

AMP-Activated Protein Kinases
Metformin
Pancreatic Neoplasms
Aspirin
Inflammation
29 Citations (Scopus)

Role of stearoyl-CoA desaturase-1 in skin integrity and whole body energy balance

Sampath, H. & Ntambi, J. M., Jan 31 2014, In : Journal of Biological Chemistry. 289, 5, p. 2482-2488 7 p.

Research output: Contribution to journalReview article

Stearoyl-CoA Desaturase
Energy balance
Skin
Lipids
Esters
7 Citations (Scopus)

SUMOylation a novel protein quality control modifier in the heart

Maejima, Y. & Sadoshima, J., Jan 1 2014, In : Circulation research. 115, 8, p. 686-689 4 p.

Research output: Contribution to journalReview article

Ubiquitin-Conjugating Enzymes
Sumoylation
Proteasome Endopeptidase Complex
Ubiquitin
Cardiac Myocytes
34 Citations (Scopus)

Targeting Mitochondrial Metabolism by Inhibiting Autophagy in BRAF -Driven Cancers

Strohecker, A. M. & White, E., Jul 2014, In : Cancer Discovery. 4, 7, p. 766-772 7 p.

Research output: Contribution to journalReview article

Autophagy
Neoplasms
Metabolomics
Oxidative Phosphorylation
Organelle Biogenesis
35 Citations (Scopus)

The Hippo signal transduction network in skeletal and cardiac muscle

Wackerhage, H., Del Re, D., Judson, R. N., Sudol, M. & Sadoshima, J., Aug 5 2014, In : Science signaling. 7, 337, re4.

Research output: Contribution to journalReview article

Signal transduction
Muscle
Signal Transduction
Myocardium
Skeletal Muscle
18 Citations (Scopus)

The importance of autophagy in cardioprotection

Sciarretta, S., Yee, D., Shenoy, V., Nagarajan, N. & Sadoshima, J., Jan 1 2014, In : High Blood Pressure and Cardiovascular Prevention. 21, 1, p. 21-28 8 p.

Research output: Contribution to journalReview article

Autophagy
Ischemia
Lysosomes
GTP-Binding Proteins
Organelles
2013
37 Citations (Scopus)

Assessing the bacterial contribution to the plastid proteome

Qiu, H., Price, D., Weber, A. P. M., Facchinelli, F., Yoon, H. S. & Bhattacharya, D., Dec 1 2013, In : Trends in Plant Science. 18, 12, p. 680-687 8 p.

Research output: Contribution to journalReview article

proteome
plastids
proteins
Proteobacteria
endosymbionts
11 Citations (Scopus)

Cancer therapy combination: Green tea and a phosphodiesterase 5 inhibitor?

Yang, C. S. & Wang, H., Feb 1 2013, In : Journal of Clinical Investigation. 123, 2, p. 556-558 3 p.

Research output: Contribution to journalReview article

Phosphodiesterase 5 Inhibitors
Tea
Laminin Receptors
Neoplasms
Therapeutics
104 Citations (Scopus)

Cardiovascular autophagy Concepts, controversies, and perspectives

Lavandero, S., Troncoso, R., Rotherme, B. A., Martinet, W., Sadoshima, J. & Hill, J. A., Jan 1 2013, In : Autophagy. 9, 10, p. 1455-1466 12 p.

Research output: Contribution to journalReview article

AMP-Activated Protein Kinases
Autophagy
NAD
Class III Phosphatidylinositol 3-Kinases
Phosphatidylinositol 3-Kinase
25 Citations (Scopus)

Detection of amino acid deprivation in the central nervous system

Anthony, T. G. & Gietzen, D. W., Jan 1 2013, In : Current Opinion in Clinical Nutrition and Metabolic Care. 16, 1, p. 96-101 6 p.

Research output: Contribution to journalReview article

Essential Amino Acids
Central Nervous System
Amino Acids
Hypothalamus
Brain
89 Citations (Scopus)

Exploiting the bad eating habits of Ras-driven cancers

White, E., Oct 1 2013, In : Genes and Development. 27, 19, p. 2065-2071 7 p.

Research output: Contribution to journalReview article

Feeding Behavior
Autophagy
Recycling
Metabolic Networks and Pathways
Glutamine
24 Citations (Scopus)

Interacting with thioredoxin-1-disease or no disease?

Zschauer, T. C., Matsushima, S., Altschmied, J., Shao, D., Sadoshima, J. & Haendeler, J., Mar 20 2013, In : Antioxidants and Redox Signaling. 18, 9, p. 1053-1062 10 p.

Research output: Contribution to journalReview article

Thioredoxins
Proteins
Reactive Oxygen Species
Cardiovascular Diseases
Peroxiredoxins
120 Citations (Scopus)

Interferon induction and function at the mucosal surface

Durbin, R. K., Kotenko, S. & Durbin, J., Sep 1 2013, In : Immunological Reviews. 255, 1, p. 25-39 15 p.

Research output: Contribution to journalReview article

Interferons
Antiviral Agents
Virus Diseases
Cytokines
Interferon-Stimulated Gene Factor 3