Research Output 1960 2020

2020

Architectured helically coiled scaffolds from elastomeric poly(butylene succinate) (PBS) copolyester via wet electrospinning

Sonseca, A., Sahay, R., Stepien, K., Bukala, J., Wcislek, A., McClain, A., Sobolewski, P., Sui, X. M., Puskas, J. E., Kohn, J., Wagner, H. D. & El Fray, M., Mar 2020, In : Materials Science and Engineering C. 108, 110505.

Research output: Contribution to journalArticle

Open Access
tissue engineering
Electrospinning
butenes
Scaffolds
smooth muscle
Moringa
Mesangial Cells
Diabetic Nephropathies
Transcriptome
Glucose

RCSB Protein Data Bank: Enabling biomedical research and drug discovery

Goodsell, D. S., Zardecki, C., Di Costanzo, L., Duarte, J. M., Hudson, B. P., Persikova, I., Segura, J., Shao, C., Voigt, M., Westbrook, J. D., Young, J. Y. & Burley, S. K., Jan 1 2020, In : Protein Science. 29, 1, p. 52-65 14 p.

Research output: Contribution to journalReview article

Drug Discovery
Biomedical Research
Databases
Proteins
Bioinformatics
2019

2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

Tang, H., Venkatesh, S., Lin, Z., Lu, X., Saeidi, H., Rather, G. M., Bertino, J. R., Lin, C. Y., Javanmard, M. & Sengupta, K., Apr 2019, 2019 IEEE Custom Integrated Circuits Conference, CICC 2019. Institute of Electrical and Electronics Engineers Inc., 8780363. (Proceedings of the Custom Integrated Circuits Conference; vol. 2019-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Magnetic sensors
Flow cytometry
Sensor arrays
Microfluidics
Cells
1 Citation (Scopus)

3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

Chen, G., Xie, W., Nah, J., Sauvat, A., Liu, P., Pietrocola, F., Sica, V., Carmona-Gutierrez, D., Zimmermann, A., Pendl, T., Tadic, J., Bergmann, M., Hofer, S. J., Domuz, L., Lachkar, S., Markaki, M., Tavernarakis, N., Sadoshima, J., Madeo, F., Kepp, O. & 1 others, Kroemer, G., Nov 7 2019, In : EMBO Molecular Medicine. 11, 11, e10469.

Research output: Contribution to journalArticle

Open Access
Caloric Restriction
Autophagy
Transcription Factors
Protein Biosynthesis
Polyphenols

Aberrant arc between the common hepatic artery and a replaced right hepatic artery resulting in misperfusion in a patient with a hepatic arterial infusion pump

Hasan, O., Greco, S., Kennedy, T., Carpizo, D., Kempf, J. & Nosher, J., Mar 1 2019, In : Surgical and Radiologic Anatomy. 41, 3, p. 355-358 4 p.

Research output: Contribution to journalArticle

Infusion Pumps
Hepatic Artery
Liver
Nuclear Medicine
Perfusion

Achieving molecular orientation in thermally extruded 3D printed objects

Ghodbane, S. A., Murthy, N. S., Dunn, M. G. & Kohn, J., Jul 3 2019, In : Biofabrication. 11, 4, 045004.

Research output: Contribution to journalArticle

Open Access
Molecular orientation
Polymers
Printing
Scaffolds
Nozzles
2 Citations (Scopus)

Activation of Protein Kinase A Stimulates SUMOylation, Expression, and Transport Activity of Organic Anion Transporter 3

Wang, H., Zhang, J. & You, G., Mar 1 2019, In : AAPS Journal. 21, 2, 30.

Research output: Contribution to journalArticle

Organic Anion Transporters
Sumoylation
Cyclic AMP-Dependent Protein Kinases
Ubiquitination
Cell Membrane

Adaptation of liquid handling robotics for high throughput customizable raft-polymerization

Tamasi, M., Kosuri, S., Upadhya, R. & Gormley, A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Robotics
Polymerization
Polymers
Throughput
Liquids

Adsorption of Fibrinogen and Fibronectin on Elastomeric Poly(butylene succinate) Copolyesters

Sobolewski, P., Murthy, N. S., Kohn, J. & El Fray, M., Jul 2 2019, In : Langmuir. 35, 26, p. 8850-8859 10 p.

Research output: Contribution to journalArticle

fibrinogen
butenes
Fibronectins
Fibrinogen
Succinic Acid
1 Citation (Scopus)

A ligand motif enables differential vascular targeting of endothelial junctions between brain and retina

Tang, F. H. F., Staquicini, F. I., Teixeira, A. A. R., Michaloski, J. S., Namiyama, G. M., Taniwaki, N. N., Setubal, J. C., Da Silva, A. M., Sidman, R. L., Pasqualini, R., Arap, W. & Giordano, R. J., Feb 5 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 6, p. 2300-2305 6 p.

Research output: Contribution to journalArticle

Blood Vessels
Retina
Ligands
Peptides
Brain

Alpha-carboxynucleoside phosphonates: Direct-acting inhibitors of viral DNA polymerases

Balzarini, J., Ford, A., Maguire, N. M., John, J., Das, K., Arnold, E., Dehaen, W. & Maguire, A., Jan 1 2019, In : Future Medicinal Chemistry. 11, 2, p. 137-154 18 p.

Research output: Contribution to journalReview article

Nucleic Acid Synthesis Inhibitors
Organophosphonates
Viral DNA
DNA-Directed DNA Polymerase
Nucleosides

A method to deliver patterned electrical impulses to Schwann cells cultured on an artificial axon

Merolli, A., Mao, Y., Voronin, G., Steele, J., Murthy, N. & Kohn, J., Jun 1 2019, In : Neural Regeneration Research. 14, 6, p. 1052-1059 8 p.

Research output: Contribution to journalArticle

Open Access
Schwann Cells
Axons
Peripheral Nerves
Neurons
Technology
17 Citations (Scopus)

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

Saito, T., Nah, J., Oka, S. I., Mukai, R., Monden, Y., Maejima, Y., Ikeda, Y., Sciarretta, S., Liu, T., Li, H., Baljinnyam, E., Fraidenraich, D., Fritzky, L., Zhai, P., Ichinose, S., Isobe, M., Hsu, C. P., Kundu, M. & Sadoshima, J., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 802-819 18 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Autophagy
Ischemia
Mitochondria
Dynamins

An anti-inflammatory nanoscaffold for enhanced stem cell transplantation and neuronal differentiation post-spinal cord injury

Yang, L., Cerqueira, S. R., Lee, J. K. & Lee, K. B., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Stem Cell Transplantation
Stem cells
Spinal Cord Injuries
Anti-Inflammatory Agents
Neural Stem Cells
2 Citations (Scopus)

An ELISA-Based Screening Platform for Ligand–Receptor Discovery

Ozgul, S., von Daake, S., Kakehi, S., Sereni, D., Denissova, N., Hanlon, C., Huang, Y. J., Everett, J. K., Yin, C., Montelione, G. T. & Comoletti, D., Jan 1 2019, Methods in Enzymology. Wand, A. J. (ed.). Academic Press Inc., p. 453-475 23 p. (Methods in Enzymology; vol. 615).

Research output: Chapter in Book/Report/Conference proceedingChapter

Screening
Enzyme-Linked Immunosorbent Assay
Adhesion
Throughput
Molecules
2 Citations (Scopus)

Announcing mandatory submission of PDBx/mmCIF format files for crystallographic depositions to the protein data bank (PDB)

Adams, P. D., Afonine, P. V., Baskaran, K., Berman, H. M., Berrisford, J., Bricogne, G., Brown, D. G., Burley, S. K., Chen, M., Feng, Z., Flensburg, C., Gutmanas, A., Hoch, J. C., Ikegawa, Y., Kengaku, Y., Krissinel, E., Kurisu, G., Liang, Y., Liebschner, D., Mak, L. & 15 others, Markley, J. L., Moriarty, N. W., Murshudov, G. N., Noble, M., Peisach, E., Persikova, I., Poon, B. K., Sobolev, O. V., Ulrich, E. L., Velankar, S., Vonrhein, C., Westbrook, J., Wojdyr, M., Yokochi, M. & Young, J. Y., Apr 1 2019, In : Acta Crystallographica Section D: Structural Biology. 75, p. 451-454 4 p.

Research output: Contribution to journalLetter

Open Access
Databases
Proteins
Data Curation
2 Citations (Scopus)
Exons
Mutation
Lung Neoplasms
N-(4-(3-chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide
HM781-36B
1 Citation (Scopus)

A novel antibody-toxin conjugate to treat mantle cell lymphoma

Rather, G. M., Lin, S. Y., Lin, H., Szekely, Z. & Bertino, J. R., Jan 1 2019, In : Frontiers in Oncology. 9, APR, 258.

Research output: Contribution to journalArticle

Open Access
Mantle-Cell Lymphoma
Immunotoxins
Heterografts
Cell Line
Neoplasms

A phase I trial of MK-2206 and hydroxychloroquine in patients with advanced solid tumors

Mehnert, J. M., Kaveney, A. D., Malhotra, J., Spencer, K., Portal, D., Goodin, S., Tan, A. R., Aisner, J., Moss, R. A., Lin, H., Bertino, J. R., Gibbon, D., Doyle, L. A., White, E. P. & Stein, M. N., Jan 1 2019, (Accepted/In press) In : Cancer chemotherapy and pharmacology.

Research output: Contribution to journalArticle

Hydroxychloroquine
Tumors
Neoplasms
Exanthema
Fatigue

A polymerization friendly dibenzoazacyclooctyne monomer for two-step bioconjugation

Kosuri, S. & Gormley, A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Azides
Cycloaddition
Polymerization
Alkynes
Cycloaddition Reaction
3 Citations (Scopus)

A Proteomic Screen of Neuronal Cell-Surface Molecules Reveals IgLONs as Structurally Conserved Interaction Modules at the Synapse

Ranaivoson, F. M., Turk, L. S., Ozgul, S., Kakehi, S., von Daake, S., Lopez, N., Trobiani, L., De Jaco, A., Denissova, N., Demeler, B., Özkan, E., Montelione, G. & Comoletti, D., Jun 4 2019, In : Structure. 27, 6, p. 893-906.e9

Research output: Contribution to journalArticle

Proteomics
Synapses
Proteins
Membrane Proteins
Protein Interaction Maps

Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease

Sagong, H. Y., Bauman, J. D., Nogales, A., Martínez-Sobrido, L., Arnold, E. & LaVoie, E. J., Jun 18 2019, In : ChemMedChem. 14, 12, p. 1204-1223 20 p.

Research output: Contribution to journalArticle

Endonucleases
Human Influenza
Influenza A virus
Viruses
Bimetals

A sequential double non-flourescent immunostaining for the easy identification of the motor component in the in vivo study of biomaterials for peripheral nerve regeneration

Merolli, A., Louro, P. & Kohn, J., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nerve Regeneration
Biocompatible Materials
Peripheral Nerves
Biomaterials
Paraffin

A surgical approach for spinal cord regeneration based on a 3d printable device able to provide a defined protective environment

Merolli, A., Varghese, B., Mao, Y. & Kohn, J., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Spinal Cord Regeneration
Equipment and Supplies
Spinal Cord Injuries
Spinal Cord
Restoration
1 Citation (Scopus)

Bioadhesive functional hydrogels: Controlled release of catechol species with antioxidant and antiinflammatory behavior

Puertas-Bartolomé, M., Benito-Garzón, L., Fung, S., Kohn, J., Vázquez-Lasa, B. & San Román, J., Dec 1 2019, In : Materials Science and Engineering C. 105, 110040.

Research output: Contribution to journalArticle

Hydrogels
antioxidants
Antioxidants
Anti-Inflammatory Agents
Polymers
1 Citation (Scopus)

Biocopolyesters of Poly(butylene succinate) Containing Long-Chain Biobased Glycol Synthesized with Heterogeneous Titanium Dioxide Catalyst

Stȩpień, K., Miles, C., McClain, A., Wiśniewska, E., Sobolewski, P., Kohn, J., Puskas, J., Wagner, H. D. & El Fray, M., Jun 17 2019, In : ACS Sustainable Chemistry and Engineering. 7, 12, p. 10623-10632 10 p.

Research output: Contribution to journalArticle

Glycols
Titanium dioxide
Polyesters
Copolymers
catalyst

Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis

Malekshah, O. M., Sarkar, S., Nomani, A., Patel, N., Javidian, P., Goedken, M., Polunas, M., Louro, P. & Hatefi, A., Oct 2019, In : Journal of Controlled Release. 311-312, p. 273-287 15 p.

Research output: Contribution to journalArticle

Enzyme Therapy
Prodrugs
Ovarian Neoplasms
Stem Cells
Neoplasm Metastasis
2 Citations (Scopus)

Biojava 5: A community driven open-source bioinformatics library

Lafita, A., Bliven, S., Prlić, A., Guzenko, D., Rose, P. W., Bradley, A., Pavan, P., Myers-Turnbull, D., Valasatava, Y., Heuer, M., Larson, M., Burley, S. K. & Duarte, J. M., Feb 2019, In : PLoS computational biology. 15, 2, e1006791.

Research output: Contribution to journalArticle

Open Access
bioinformatics
Bioinformatics
Computational Biology
Open Source
Libraries
4 Citations (Scopus)

Biphasic dynamics of macrophage immunometabolism during Mycobacterium tuberculosis infection

Shi, L., Jiang, Q., Bushkin, Y., Subbian, S. & Tyagi, S., Mar 1 2019, In : mBio. 10, 2, e02550-18.

Research output: Contribution to journalArticle

Open Access
Mycobacterium Infections
Mycobacterium tuberculosis
Macrophages
Glycolysis
Virulence

Both gain and loss of Nampt function promote pressure overload-induced heart failure

Byun, J., Oka, S. I., Imai, N., Huang, C. Y., Ralda, G., Zhai, P., Ikeda, Y., Ikeda, S. & Sadoshima, J., Jan 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 4, p. H711-H725

Research output: Contribution to journalArticle

Niacinamide
Transferases
Heart Failure
Pressure
Sirtuin 1
7 Citations (Scopus)

Cardiomyopathy in obesity, insulin resistance and diabetes

Nakamura, M. & Sadoshima, J., Jan 1 2019, In : Journal of Physiology.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Cardiomyopathies
Insulin Resistance
Obesity
Heart Failure
1 Citation (Scopus)

Checking in on Lenalidomide in Diffuse Large B Cell Lymphoma

Goldfinger, M., Xu, M., Bertino, J. R. & Cooper, D. L., Jun 2019, In : Clinical Lymphoma, Myeloma and Leukemia. 19, 6, p. e307-e311

Research output: Contribution to journalComment/debate

Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Vincristine
Prednisone
Doxorubicin
1 Citation (Scopus)

Combinatorial therapy of zinc metallochaperones with mutant p53 reactivation and diminished copper binding

Zaman, S., Yu, X., Bencivenga, A. F., Blanden, A. R., Liu, Y., Withers, T., Na, B., Blayney, A. J., Gilleran, J., Boothman, D. A., Loh, S. N., Kimball, S. D. & Carpizo, D. R., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 8, p. 1355-1365 11 p.

Research output: Contribution to journalArticle

Metallochaperones
Zinc
Copper
Drug Therapy
Radiation
1 Citation (Scopus)

Combining Evolutionary Covariance and NMR Data for Protein Structure Determination

Huang, Y. J., Brock, K. P., Ishida, Y., Swapna, G. V. T., Inouye, M., Marks, D. S., Sander, C. & Montelione, G. T., Jan 1 2019, Methods in Enzymology. Wand, A. J. (ed.). Academic Press Inc., p. 363-392 30 p. (Methods in Enzymology; vol. 614).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nuclear magnetic resonance
Proteins
X ray crystallography
X Ray Crystallography
Excited states
1 Citation (Scopus)

Comprehensive 3D-QSAR Model Predicts Binding Affinity of Structurally Diverse Sigma 1 Receptor Ligands

Peng, Y., Dong, H. & Welsh, W. J., Jan 28 2019, In : Journal of Chemical Information and Modeling. 59, 1, p. 486-497 12 p.

Research output: Contribution to journalArticle

activity structure
Ligands
drug
OECD
indication
1 Citation (Scopus)

Comprehensive identification of protein disulfide bonds with pepsin/trypsin digestion, Orbitrap HCD and Spectrum Identification Machine

Cui, C., Liu, T., Chen, T., Lu, J., Casaren, I., Lima, D. B., Carvalho, P. C., Beuve, A. & Li, H., Apr 30 2019, In : Journal of Proteomics. 198, p. 78-86 9 p.

Research output: Contribution to journalArticle

Pepsin A
Disulfides
Trypsin
Digestion
Peptides

Conditional survival analysis of metastatic colorectal cancer patients living ≥24 months: A single institutional study

Ali, N. D., Donohue, K., Zandieh, S., Chen, C., Moore, D., Poplin, E., Shah, M. M., Nosher, J., Gui, B., Jabbour, S. K., Spencer, K. & Carpizo, D. R., Jun 1 2019, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 42, 6, p. 512-518 7 p.

Research output: Contribution to journalArticle

Survival Analysis
Colorectal Neoplasms
Survival
Neoplasms
Databases

Contribution of DNMT1 to Neuropathic Pain Genesis Partially through Epigenetically Repressing Kcna2 in Primary Afferent Neurons

Sun, L., Gu, X., Pan, Z., Guo, X., Liu, J., Atianjoh, F. E., Wu, S., Mo, K., Xu, B., Liang, L., Bekker, A. & Tao, Y. X., Aug 14 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 33, p. 6595-6607 13 p.

Research output: Contribution to journalArticle

Afferent Neurons
Diagnosis-Related Groups
Neuralgia
Methyltransferases
DNA Methylation
2 Citations (Scopus)

Contribution of dorsal root ganglion octamer transcription factor 1 to neuropathic pain after peripheral nerve injury

Yuan, J., Wen, J., Wu, S., Mao, Y., Mo, K., Li, Z., Su, S., Gu, H., Ai, Y., Bekker, A., Zhang, W. & Tao, Y., Feb 1 2019, In : Pain. 160, 2, p. 375-384 10 p.

Research output: Contribution to journalArticle

Octamer Transcription Factor-1
Peripheral Nerve Injuries
Spinal Ganglia
Neuralgia
Hyperalgesia

Controlled cell migration within cell selective hydrogels

Pashuck, E. T., Fung, S. L., Joshi, N. S. & Kohn, J., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrogels
Biocompatible Materials
Biomaterials
Cell Movement
Cysteine
Open Access
Hydrogen bonds
4 Citations (Scopus)

Cystinuria: genetic aspects, mouse models, and a new approach to therapy

Sahota, A., Tischfield, J., Goldfarb, D. S., Ward, M. D. & Hu, L., Feb 5 2019, In : Urolithiasis. 47, 1, p. 57-66 10 p.

Research output: Contribution to journalReview article

Cystinuria
Cystine
Therapeutics
Crystallization
Diamide
20 Citations (Scopus)

D3R Grand Challenge 3: blind prediction of protein–ligand poses and affinity rankings

Gaieb, Z., Parks, C. D., Chiu, M., Yang, H., Shao, C., Walters, W. P., Lambert, M. H., Nevins, N., Bembenek, S. D., Ameriks, M. K., Mirzadegan, T., Burley, S. K., Amaro, R. E. & Gilson, M. K., Jan 15 2019, In : Journal of Computer-Aided Molecular Design. 33, 1

Research output: Contribution to journalArticle

cathepsin S
Teaching Rounds
ranking
Drug Design
Protein S
3 Citations (Scopus)
High-Throughput Nucleotide Sequencing
Peptide Hydrolases
Learning
Hepacivirus
Yeasts

Delivery of neurotrophic factors in a silk-based nerve conduit for peripheral nerve repair

Carvalho, C. R., Chang, W., Reis, R. L., Oliveira, J. M. & Kohn, J., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Silk
Nerve Growth Factors
Peripheral Nerves
Repair
Nerve Regeneration
8 Citations (Scopus)

De novo protein design by citizen scientists

Koepnick, B., Flatten, J., Husain, T., Ford, A., Silva, D. A., Bick, M. J., Bauer, A., Liu, G., Ishida, Y., Boykov, A., Estep, R. D., Kleinfelter, S., Nørgård-Solano, T., Wei, L., Players, F., Montelione, G., DiMaio, F., Popović, Z., Khatib, F., Cooper, S. & 1 others, Baker, D., Jun 20 2019, In : Nature. 570, 7761, p. 390-394 5 p.

Research output: Contribution to journalLetter

Proteins
Synthetic Genes
Peptides
Creativity
Protein Folding
1 Citation (Scopus)

Design, synthesis, evaluation, and structural studies of C2-Symmetric Small molecule inhibitors of programmed cell death-1/programmed death-ligand 1 protein-protein interaction

Basu, S., Yang, J., Xu, B., Magiera-Mularz, K., Skalniak, L., Musielak, B., Kholodovych, V., Holak, T. A. & Hu, L., Aug 8 2019, In : Journal of medicinal chemistry. 62, 15, p. 7250-7263 14 p.

Research output: Contribution to journalArticle

CD274 Antigen
Fluorescence
Coculture Techniques
Proteins
Inhibitory Concentration 50

Design and evaluation of a CXCR4 targeting peptide 4DV3 as an HIV entry inhibitor and a ligand for targeted drug delivery

Heon Lee, I., Palombo, M. S., Zhang, X., Szekely, Z. & Sinko, P., May 1 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 138, p. 11-22 12 p.

Research output: Contribution to journalArticle

Virus Internalization
HIV
Ligands
Peptides
Pharmaceutical Preparations

Designing polymers for the activation of, and selective resorption by, osteoclasts for bone regeneration

Fung, S. L., Martin, D., Mahat, A., Mishra, P., Cohen, J., Pashuck, E. T., Mao, Y., Moghe, P., Merolli, A. & Kohn, J., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bone Regeneration
Osteoclasts
Polymers
Bone
Chemical activation