Clinical Investigations and Precision Therapeutics Program, CINJ

Research Output 1976 2019

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Review article
2011
191 Citations (Scopus)

Antioxidants in foods: State of the science important to the food industry

Finley, J. W., Kong, A-N., Hintze, K. J., Jeffery, E. H., Ji, L. L. & Lei, X. G., Jul 13 2011, In : Journal of agricultural and food chemistry. 59, 13, p. 6837-6846 10 p.

Research output: Contribution to journalReview article

Food Technology
Food Industry
food industry
reactive oxygen species
Reactive Oxygen Species
2 Citations (Scopus)

Immunotherapy in the treatment of advanced prostate cancer

Djavan, B., Nelson, K., Kazzazi, A., Bruhn, A., Sadri, H., Gomez-Pinillos, A. & Ferrari, A., Oct 1 2011, In : Canadian Journal of Urology. 18, 5, p. 5865-5874 10 p.

Research output: Contribution to journalReview article

Immunotherapy
Prostatic Neoplasms
Therapeutics
Radiotherapy
Physicians
844 Citations (Scopus)

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D'Amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, Colombel, J. F., Denson, L. A., De Vos, M., Dubinsky, M., Edwards, C., Ellinghaus, D., Fehrmann, R. S. N., Floyd, J. A. B., Florin, T., Franchimont, D., Franke, L., Georges, M., Glas, J., Glazer, N. L., Guthery, S. L., Haritunians, T., Hayward, N. K., Hugot, J. P., Jobin, G., Laukens, D., Lawrance, I., Lémann, M., Levine, A., Libioulle, C., Louis, E., McGovern, D. P., Milla, M., Montgomery, G. W., Morley, K. I., Mowat, C., Ng, A., Newman, W., Ophoff, R. A., Papi, L., Palmieri, O., Peyrin-Biroulet, L., Panés, J., Phillips, A., Prescott, N. J., Proctor, D. D., Roberts, R., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Schumm, P., Seibold, F., Sharma, Y., Simms, L. A., Seielstad, M., Steinhart, A. H., Targan, S. R., Van Den Berg, L. H., Vatn, M., Verspaget, H., Walters, T., Wijmenga, C., Wilson, D. C., Westra, H. J., Xavier, R. J., Zhao, Z. Z., Ponsioen, C. Y., Andersen, V., Torkvist, L., Gazouli, M., Anagnou, N. P., Karlsen, T. H., Kupcinskas, L., Sventoraityte, J., Mansfield, J. C., Kugathasan, S., Silverberg, M. S., Halfvarson, J., Rotter, J. I., Mathew, C. G., Griffiths, A. M., Gearry, R., Ahmad, T., Brant, S., Chamaillard, M., Satsangi, J., Cho, J. H., Schreiber, S., Daly, M. J., Barrett, J. C., Parkes, M., Annese, V., Hakonarson, H., Radford-Smith, G., Duerr, R. H., Vermeire, S., Weersma, R. K. & Rioux, J. D., Jan 1 2011, In : Nature genetics. 43, 3, p. 246-252 7 p.

Research output: Contribution to journalReview article

Ulcerative Colitis
Meta-Analysis
Genome-Wide Association Study
Quantitative Trait Loci
Inflammatory Bowel Diseases
34 Citations (Scopus)

Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer

Saw, C. L. L. & Kong, A-N., Mar 1 2011, In : Expert Opinion on Therapeutic Targets. 15, 3, p. 281-295 15 p.

Research output: Contribution to journalReview article

Colorectal Neoplasms
Antioxidants
Detoxification
Vegetables
Mountings
2010

Adjuvant chemotherapy for early stage breast cancer: Current trends and future directions

Wong, S. T. & Toppmeyer, D., Mar 1 2010, In : Current Breast Cancer Reports. 2, 1, p. 16-24 9 p.

Research output: Contribution to journalReview article

Adjuvant Chemotherapy
Molecular Targeted Therapy
Breast Neoplasms
Neoplasms
Recurrence
35 Citations (Scopus)
Panax
Action Potentials
Oxidative Stress
Anti-Inflammatory Agents
Neoplasms
4 Citations (Scopus)

Combinatorial vascular targeting in translational medicine

Staquicini, F. I., Moeller, B. J., Arap, W. & Pasqualini, R., Jul 1 2010, In : Proteomics - Clinical Applications. 4, 6-7, p. 626-632 7 p.

Research output: Contribution to journalReview article

Bacteriophages
Translational Medical Research
Medicine
Blood Vessels
Display devices
12 Citations (Scopus)

How does public policy impact cervical screening and vaccination strategies?

Herzog, T. J., Huh, W. K. & Einstein, M., Jan 1 2010, In : Gynecologic Oncology. 119, 2, p. 175-180 6 p.

Research output: Contribution to journalReview article

Public Policy
Uterine Cervical Neoplasms
Vaccination
Early Detection of Cancer
Guidelines
20 Citations (Scopus)

Issues in cervical cancer incidence and treatment in HIV

Einstein, M. & Phaëton, R., Sep 1 2010, In : Current opinion in oncology. 22, 5, p. 449-455 7 p.

Research output: Contribution to journalReview article

Uterine Cervical Neoplasms
HIV
Incidence
Therapeutics
Highly Active Antiretroviral Therapy
8 Citations (Scopus)

Ixabepilone, a new treatment option for metastatic breast cancer

Toppmeyer, D. & Goodin, S., Oct 1 2010, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 33, 5, p. 516-521 6 p.

Research output: Contribution to journalReview article

Taxoids
Breast Neoplasms
Anthracyclines
Prostatic Neoplasms
Epothilones
8 Citations (Scopus)

Management of locally recurrent kidney cancer

Singer, E. & Bratslavsky, G., Feb 1 2010, In : Current urology reports. 11, 1, p. 15-21 7 p.

Research output: Contribution to journalReview article

Kidney Neoplasms
Kidney
Nephrectomy
Investigational Therapies
Nephrons
266 Citations (Scopus)

Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention

Cheung, K. L. & Kong, A-N., Mar 1 2010, In : AAPS Journal. 12, 1, p. 87-97 11 p.

Research output: Contribution to journalReview article

Chemoprevention
Carcinogenesis
Isothiocyanates
Neoplasms
Drug and Narcotic Control
53 Citations (Scopus)

Overcoming the barriers to HPV vaccination in high-risk populations in the US

Downs, L. S., Scarinci, I., Einstein, M., Collins, Y. & Flowers, L., Jun 1 2010, In : Gynecologic Oncology. 117, 3, p. 486-490 5 p.

Research output: Contribution to journalReview article

Uterine Cervical Neoplasms
Vaccination
Population
Immunization Programs
Poverty
161 Citations (Scopus)

Phytochemicals: Cancer chemoprevention and suppression of tumor onset and metastasis

Shu, L., Cheung, K. L., Khor, T. O., Chen, C. & Kong, A-N., Sep 1 2010, In : Cancer and Metastasis Reviews. 29, 3, p. 483-502 20 p.

Research output: Contribution to journalReview article

Chemoprevention
Phytochemicals
Neoplasm Metastasis
Neoplasms
Epithelial-Mesenchymal Transition
48 Citations (Scopus)

Primary cutaneous and systemic anaplastic large cell lymphoma

Querfeld, C., Khan, I., Mahon, B., Nelson, B. P., Rosen, S. T. & Evens, A., Jan 1 2010, In : ONCOLOGY. 24, 7

Research output: Contribution to journalReview article

Primary Cutaneous Anaplastic Large Cell Lymphoma
Anaplastic Large-Cell Lymphoma
Skin Diseases
Lymphomatoid Papulosis
Chromosomes, Human, Pair 5
13 Citations (Scopus)

Radioimmunotherapy for the treatment of non-Hodgkin lymphoma: Current status and future applications

Ahmed, S., Winter, J. N., Gordon, L. I. & Evens, A., Jul 1 2010, In : Leukemia and Lymphoma. 51, 7, p. 1163-1177 15 p.

Research output: Contribution to journalReview article

Radioimmunotherapy
Non-Hodgkin's Lymphoma
Follicular Lymphoma
Therapeutics
Antibodies, Monoclonal, Humanized
129 Citations (Scopus)

Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: Antioxidant coupled with antiinflammatory

Hu, R., Saw, C. L. L., Yu, R. & Kong, A-N., Dec 1 2010, In : Antioxidants and Redox Signaling. 13, 11, p. 1679-1698 20 p.

Research output: Contribution to journalReview article

NF-E2-Related Factor 2
Chemoprevention
Anti-Inflammatory Agents
Antioxidants
Neoplasms
11 Citations (Scopus)

What is the role of HPV typing in the United States now and in the next five years in a vaccinated population?

Huh, W., Einstein, M., Herzog, T. J. & Franco, E. L., Jun 1 2010, In : Gynecologic Oncology. 117, 3, p. 481-485 5 p.

Research output: Contribution to journalReview article

Uterine Cervical Neoplasms
Population
Health Personnel
Vaccination
Costs and Cost Analysis
478 Citations (Scopus)

Xenobiotic, bile acid, and cholesterol transporters: Function and regulation

Klaassen, C. D. & Aleksunes, L., Mar 1 2010, In : Pharmacological Reviews. 62, 1, p. 1-96 96 p.

Research output: Contribution to journalReview article

Organic Cation Transporter 1
Xenobiotics
ATP-Binding Cassette Transporters
Cholesterol
Toxicology
2009

Application of proteomic techniques to human tissues

Richardson, A. M., Rodriguez-Canales, J., Gannot, G., Libutti, S., Chuaqui, R. F. & Tangrea, M. A., Dec 4 2009, In : Journal of Organ Dysfunction. 5, 2, p. 110-118 9 p.

Research output: Contribution to journalReview article

Proteomics
Technology
Mass Spectrometry
Tissue Preservation
Protein Array Analysis
146 Citations (Scopus)

Cancer-preventive activities of tocopherols and tocotrienols

Ju, J., Picinich, S. C., Yang, Z., Zhao, Y., Suh, N., Kong, A-N. & Yang, C., Sep 11 2009, In : Carcinogenesis. 31, 4, p. 533-542 10 p.

Research output: Contribution to journalReview article

Tocotrienols
Tocopherols
Neoplasms
Vitamin E
Animal Models
133 Citations (Scopus)

Clinician's guide to human papillomavirus immunology: knowns and unknowns

Einstein, M., Schiller, J. T., Viscidi, R. P., Strickler, H. D., Coursaget, P., Tan, T., Halsey, N. & Jenkins, D., Jun 1 2009, In : The Lancet infectious diseases. 9, 6, p. 347-356 10 p.

Research output: Contribution to journalReview article

Allergy and Immunology
Immune System
Infection
Papillomaviridae
Uterine Cervical Neoplasms
421 Citations (Scopus)

Intravascular delivery of particulate systems: Does geometry really matter?

Decuzzi, P., Pasqualini, R., Arap, W. & Ferrari, M., Jan 1 2009, In : Pharmaceutical research. 26, 1, p. 235-243 9 p.

Research output: Contribution to journalReview article

Geometry
Surface Properties
Bacteriophages
Nanoparticles
Libraries
7 Citations (Scopus)

Ligand-directed Cancer Gene Therapy to Angiogenic Vasculature

Driessen, W. H. P., Ozawa, M. G., Arap, W. & Pasqualini, R., Dec 14 2009, In : Advances in Genetics. 67, C, p. 103-121 19 p.

Research output: Contribution to journalReview article

Neoplasm Genes
Genetic Therapy
Ligands
Bacteriophages
Blood Vessels
32 Citations (Scopus)

Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease

Carpizo, D. & D'Angelica, M., Sep 1 2009, In : Annals of Surgical Oncology. 16, 9, p. 2411-2421 11 p.

Research output: Contribution to journalReview article

Colorectal Neoplasms
Liver
Liver Diseases
Drug Therapy
PubMed
68 Citations (Scopus)

Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease

Carpizo, D. & D'Angelica, M., Aug 1 2009, In : The Lancet Oncology. 10, 8, p. 801-809 9 p.

Research output: Contribution to journalReview article

Colorectal Neoplasms
Liver
Neoplasm Metastasis
Liver Diseases
Recurrence
15 Citations (Scopus)

MIRD commentary: Proposed name for a dosimetry unit applicable to deterministic biological effects-the barendsen (Bd)

Sgouros, G., Howell, R., Bolch, W. E., Fisher, D. R., Brill, A. B., Meredith, R. F., Wessels, B. W. & Zanzonico, P. B., Mar 1 2009, In : Journal of Nuclear Medicine. 50, 3, p. 485-487 3 p.

Research output: Contribution to journalReview article

Names
Radiation
Radiation Dosage
Nuclear Medicine
Ionizing Radiation
456 Citations (Scopus)

Molecular mechanisms of Nrf2-mediated antioxidant response

Li, W. & Kong, A-N., Feb 1 2009, In : Molecular Carcinogenesis. 48, 2, p. 91-104 14 p.

Research output: Contribution to journalReview article

Oxidation-Reduction
Antioxidants
Ubiquitination
Transcription Factors
Cullin Proteins
59 Citations (Scopus)

Novel chemotherapy approaches for cervical cancer

Movva, S., Rodriguez-Rust, L., Arias-Pulido, H. & Verschraegen, C., Aug 18 2009, In : Cancer. 115, 14, p. 3166-3180 15 p.

Research output: Contribution to journalReview article

Platinum
Uterine Cervical Neoplasms
Drug Therapy
Therapeutic Uses
Standard of Care
98 Citations (Scopus)

Nrf2 plays an important role in coordinated regulation of phase II drug metabolism enzymes and phase III drug transporters

Shen, G. & Kong, A-N., Oct 19 2009, In : Biopharmaceutics and Drug Disposition. 30, 7, p. 345-355 11 p.

Research output: Contribution to journalReview article

Enzymes
Pharmaceutical Preparations
NF-E2-Related Factor 2
Antioxidant Response Elements
Xenobiotics
9 Citations (Scopus)

Targeting cancer-specific synthetic lethality in double-strand DNA break repair

Moeller, B. J., Pasqualini, R. & Arap, W., Jun 15 2009, In : Cell Cycle. 8, 12, p. 1872-1876 5 p.

Research output: Contribution to journalReview article

Double-Stranded DNA Breaks
DNA Repair
Neoplasms
Therapeutics
Carcinogenesis
2008
17 Citations (Scopus)
Cancer Vaccines
Uterine Cervical Neoplasms
Infection
Oncogenic Viruses
Antibody Formation
71 Citations (Scopus)

Biological/chemopreventive activity of stilbenes and their effect on colon cancer

Rimando, A. M. & Suh, N., Oct 1 2008, In : Planta Medica. 74, 13, p. 1635-1643 9 p.

Research output: Contribution to journalReview article

Stilbenes
Bioactivity
Colonic Neoplasms
Fruit
Fruits
56 Citations (Scopus)

Dietary cancer chemopreventive agents - Targeting inflammation and nrf2 signaling pathway

Khor, T. O., Yu, S. & Kong, A-N., Oct 1 2008, In : Planta Medica. 74, 13, p. 1540-1547 8 p.

Research output: Contribution to journalReview article

Phytochemicals
Inflammation
Anti-Inflammatory Agents
Carcinogenesis
Pharmaceutical Preparations
61 Citations (Scopus)

Does the renin-angiotensin system participate in regulation of human vasculogenesis and angiogenesis?

Khakoo, A. Y., Sidman, R. L., Pasqualini, R. & Arap, W., Nov 15 2008, In : Cancer Research. 68, 22, p. 9112-9115 4 p.

Research output: Contribution to journalReview article

Renin-Angiotensin System
Hypertension
Neonatology
Cardiology
Blood Vessels
3 Citations (Scopus)

Ixabepilone in metastatic breast cancer: Complement or alternative to taxanes?

Tan, A. R. & Toppmeyer, D., Nov 1 2008, In : Clinical Cancer Research. 14, 21, p. 6725-6729 5 p.

Research output: Contribution to journalReview article

Antineoplastic Combined Chemotherapy Protocols
Tubulin Modulators
Epothilones
Taxoids
Breast Neoplasms
3 Citations (Scopus)

KidneyMatch.com: The ethics of solicited organ donations

Dees, R. H. & Singer, E., Jun 1 2008, In : Journal of Clinical Ethics. 19, 2, p. 141-149 9 p.

Research output: Contribution to journalReview article

Directed Tissue Donation
Choice Behavior
Altruism
organ donation
Personal Autonomy
152 Citations (Scopus)

Optical contrast agents and imaging systems for detection and diagnosis of cancer

Pierce, M., Javier, D. J. & Richards-Kortum, R., Nov 1 2008, In : International Journal of Cancer. 123, 9, p. 1979-1990 12 p.

Research output: Contribution to journalReview article

Optical Imaging
Contrast Media
Molecular Imaging
Biochemical Phenomena
Neoplasms
65 Citations (Scopus)

Treatment of Hodgkin lymphoma: The past, present, and future

Evens, A., Hutchings, M. & Diehl, V., Aug 8 2008, In : Nature Clinical Practice Oncology. 5, 9, p. 543-556 14 p.

Research output: Contribution to journalReview article

Hodgkin Disease
Therapeutics
Translational Medical Research
Disease-Free Survival
Randomized Controlled Trials
2007
393 Citations (Scopus)

American Cancer Society Guideline for Human Papillomavirus (HPV) Vaccine Use to Prevent Cervical Cancer and Its Precursors

Saslow, D., Castle, P. E., Cox, J. T., Davey, D. D., Einstein, M., Ferris, D. G., Goldie, S. J., Harper, D. M., Kinney, W., Moscicki, A. B., Noller, K. L., Wheeler, C. M., Ades, T., Andrews, K. S., Doroshenk, M. K., Kahn, K. G., Schmidt, C., Shafey, O., Smith, R. A., Partridge, E. E. & 1 others, Garcia, F., Jan 1 2007, In : Ca-A Cancer Journal for Clinicians. 57, 1, p. 7-28 22 p.

Research output: Contribution to journalReview article

Papillomavirus Vaccines
Uterine Cervical Neoplasms
Guidelines
Cervical Intraepithelial Neoplasia
1 Citation (Scopus)

Application of pharmacogenomics to dietary cancer chemoprevention

Prawan, A., Khor, T. O., Li, W. & Kong, A-N., Sep 1 2007, In : Current Pharmacogenomics. 5, 3, p. 198-200 3 p.

Research output: Contribution to journalReview article

Pharmacogenetics
Chemoprevention
Phytochemicals
Neoplasms
Carcinogenesis
108 Citations (Scopus)

Cancer chemoprevention by phytochemicals: Potential molecular targets, biomarkers and animal models

Kwon, K. H., Barve, A., Yu, S., Huang, M. T. & Kong, A-N., Sep 1 2007, In : Acta Pharmacologica Sinica. 28, 9, p. 1409-1421 13 p.

Research output: Contribution to journalReview article

Molecular Models
Chemoprevention
Phytochemicals
Animal Models
Biomarkers
57 Citations (Scopus)

Dextromethorphan: A review of N-methyl-D-aspartate receptor antagonist in the management of pain

Siu, A. & Drachtman, R., Mar 1 2007, In : CNS Drug Reviews. 13, 1, p. 96-106 11 p.

Research output: Contribution to journalReview article

Dextromethorphan
Pain Management
N-Methyl-D-Aspartate Receptors
Antitussive Agents
Excitatory Amino Acids
30 Citations (Scopus)

Molecular targets on blood vessels for cancer therapies in clinical trials

Sato, M., Arap, W. & Pasqualini, R., Oct 1 2007, In : ONCOLOGY. 21, 11, p. 1346-1352 7 p.

Research output: Contribution to journalReview article

Blood Vessels
Clinical Trials
Neoplasms
Ligands
CD13 Antigens
128 Citations (Scopus)
Cytoprotection
Oxidation-Reduction
NF-E2-Related Factor 2
Phytochemicals
Neoplasms
13 Citations (Scopus)

Relapsed and refractory Hodgkin Lymphoma: Transplantation strategies and novel therapeutic options

David, K., Mauro, L. & Evens, A., Oct 1 2007, In : Current treatment options in oncology. 8, 5, p. 352-374 23 p.

Research output: Contribution to journalReview article

Hodgkin Disease
Hematopoietic Stem Cell Transplantation
Transplantation
Survival Rate
Drug Therapy
43 Citations (Scopus)

Targeting carcinogen metabolism by dietary cancer preventive compounds

Yu, S. & Kong, A-N., Aug 1 2007, In : Current Cancer Drug Targets. 7, 5, p. 416-424 9 p.

Research output: Contribution to journalReview article

Carcinogens
Enzymes
Neoplasms
Carcinogenesis
Xenobiotics
2006
57 Citations (Scopus)

Delayed neurotoxicity associated with therapy for children with acute lymphoblastic leukemia

Cole, P. & Kamen, B. A., Nov 3 2006, In : Mental Retardation and Developmental Disabilities Research Reviews. 12, 3, p. 174-183 10 p.

Research output: Contribution to journalReview article

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Craniospinal Irradiation
Folic Acid Antagonists
Therapeutics
Nucleosides
191 Citations (Scopus)

Display technologies: Application for the discovery of drug and gene delivery agents

Sergeeva, A., Kolonin, M. G., Molldrem, J. J., Pasqualini, R. & Arap, W., Dec 30 2006, In : Advanced Drug Delivery Reviews. 58, 15, p. 1622-1654 33 p.

Research output: Contribution to journalReview article

Genetic Association Studies
Drug Discovery
Technology
Proteome
Bacteriophages
6 Citations (Scopus)

Ethical issues in palliative care

Demme, R. A., Singer, E., Greenlaw, J. & Quill, T. E., Mar 1 2006, In : Anesthesiology Clinics of North America. 24, 1, p. 129-144 16 p.

Research output: Contribution to journalReview article

Palliative Care
Ethics
Double Effect Principle
Perioperative Care
Hypnotics and Sedatives