Ernest Mario School of Pharmacy, Medicinal Chemistry

Fingerprint Dive into the research topics where Ernest Mario School of Pharmacy, Medicinal Chemistry is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Type I DNA Topoisomerase Medicine & Life Sciences
Prodrugs Medicine & Life Sciences
Cytotoxicity Chemical Compounds
Derivatives Chemical Compounds
Phenanthridines Medicine & Life Sciences
Antineoplastic Agents Medicine & Life Sciences
Nitroreductases Medicine & Life Sciences
G-Quadruplexes Medicine & Life Sciences

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Projects 1975 2022

Cystinuria
Diamide
Cystine
Crystallization
Urine
Assays
Fluorescence
Polarization
Screening
Antioxidant Response Elements

Research Output 1977 2019

4 Citations (Scopus)

Cystinuria: genetic aspects, mouse models, and a new approach to therapy

Sahota, A., Tischfield, J., Goldfarb, D. S., Ward, M. D. & Hu, L., Feb 5 2019, In : Urolithiasis. 47, 1, p. 57-66 10 p.

Research output: Contribution to journalReview article

Cystinuria
Cystine
Therapeutics
Crystallization
Diamide
1 Citation (Scopus)

Design, synthesis, evaluation, and structural studies of C2-Symmetric Small molecule inhibitors of programmed cell death-1/programmed death-ligand 1 protein-protein interaction

Basu, S., Yang, J., Xu, B., Magiera-Mularz, K., Skalniak, L., Musielak, B., Kholodovych, V., Holak, T. A. & Hu, L., Aug 8 2019, In : Journal of medicinal chemistry. 62, 15, p. 7250-7263 14 p.

Research output: Contribution to journalArticle

CD274 Antigen
Fluorescence
Coculture Techniques
Proteins
Inhibitory Concentration 50
13 Citations (Scopus)

Immunomodulators targeting the PD-1/PD-L1 protein-protein interaction: From antibodies to small molecules

Yang, J. & Hu, L., Jan 1 2019, In : Medicinal Research Reviews. 39, 1, p. 265-301 37 p.

Research output: Contribution to journalReview article

Immunologic Factors
Antibodies
Proteins
Peptidomimetics
Neoplasms