Ernest Mario School of Pharmacy, Medicinal Chemistry

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Type I DNA Topoisomerase Medicine & Life Sciences
Prodrugs Medicine & Life Sciences
Cytotoxicity Chemical Compounds
Phenanthridines Medicine & Life Sciences
Derivatives Chemical Compounds
Antineoplastic Agents Medicine & Life Sciences
Nitroreductases Medicine & Life Sciences
G-Quadruplexes Medicine & Life Sciences

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Projects 2007 2012

Assays
Fluorescence
Polarization
Screening
Antioxidant Response Elements
Eph Family Receptors
Nervous System
Ephrins
Physiological Phenomena
Nervous System Diseases
Assays
Oxidative stress
Screening
Enzymes
Proteins

Research Output 1973 2019

3 Citations (Scopus)

Cystinuria: genetic aspects, mouse models, and a new approach to therapy

Sahota, A., Tischfield, J., Goldfarb, D. S., Ward, M. D. & Hu, L., Feb 5 2019, In : Urolithiasis. 47, 1, p. 57-66 10 p.

Research output: Contribution to journalReview article

Cystinuria
Cystine
Therapeutics
Crystallization
Diamide
2 Citations (Scopus)

Immunomodulators targeting the PD-1/PD-L1 protein-protein interaction: From antibodies to small molecules

Yang, J. & Hu, L., Jan 1 2019, In : Medicinal Research Reviews. 39, 1, p. 265-301 37 p.

Research output: Contribution to journalReview article

Immunologic Factors
Antibodies
Proteins
Peptidomimetics
Neoplasms
1 Citation (Scopus)

Design, synthesis, and evaluation of L-cystine diamides as L-cystine crystallization inhibitors for cystinuria

Yang, Y., Albanyan, H., Lee, S., Aloysius, H., Liang, J. J., Kholodovych, V., Sahota, A. & Hu, L., May 1 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 8, p. 1303-1308 6 p.

Research output: Contribution to journalArticle

Cystinuria
Diamide
Cystine
Crystallization
Methylation