Projects per year
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Dive into the research topics where Ernest Mario School of Pharmacy, Medicinal Chemistry is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
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Profiles
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Hijacking Post-translational Arginylation for Targeted Protein Degradation
Lin, Z. (PI) & Lyu, D. D. (CoPI)
8/2/24 → 7/31/26
Project: Research project
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Development of dual inhibitors targeting the viral main protease and the host cathepsin L as SARS-CoV-2 antivirals
Wang, J. J. (PI) & Wang, J. (CoPI)
National Institute of Allergy and Infectious Diseases
8/1/21 → 7/31/26
Project: Research project
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Development and Application of Chemical Biology Approaches for Understanding Protein Arginylation
Garcia, B. A. (PI), Lyu, D. D. (CoPI) & Lin, Z. (CoPI)
National Heart, Lung, and Blood Institute
1/25/25 → 11/30/25
Project: Research project
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Discovery and development of inhibitors of heat shock factor 1 by a fluorescence polarization assay
Chan, G. H. & Moschitto, M. J., 2025, (Accepted/In press) In: Medicinal Chemistry Research.Research output: Contribution to journal › Article › peer-review
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Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease
Tan, H., Zhang, Q., Georgiou, K., Zhang, S., Li, K., Lambrinidis, G., Kolocouris, A., Deng, X. & Wang, J., Dec 2025, In: Nature communications. 16, 1, 4548.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
Tan, B., Zhang, X., Ansari, A., Jadhav, P., Tan, H., Li, K., Chopra, A., Ford, A., Chi, X., Ruiz, F. X., Arnold, E., Deng, X. & Wang, J., Mar 29 2024, In: Science. 383, 6690, p. 1434-1440 7 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations