New Jersey Medical School (NJMS), Pharmacology

Projects

Projects per year 1989 1989 1990 1999 2008 2009 2013 2018 2019 2022

• 120 Finished

Projects per year

Search results

• Finished

  Novel Neuromodulation Treatment of Age Related Vestibular Loss to Improve Balance and Gait in Elderly Individuals

  Serrador, J.

  9/30/21 → 5/31/22

  Project: Research project

  • Electric Stimulation 100%
  • Gait 62%
  • Elderly 59%
  • Reflex 19%
  • Neurons 13%

• Trem2-mediated microglia-neuronal axis in Alzheimer disease pathogenesis

  D'Adamio, L.

  8/1/21 → 4/30/22

  Project: Research project

  • Flavin-Adenine Dinucleotide 100%
  • Microglia 75%
  • Amyloid Plaques 40%
  • Poisons 27%
  • Neurofibrillary Tangles 22%

• Intranasal LIF to improve neurological recovery from perinatal hypoxia-ischema

  Levison, S.

  National Institute of Neurological Disorders and Stroke

  3/1/21 → 2/28/22

  Project: Research project

  • Leukemia 100%
  • Hypoxia 56%
  • Neural Stem Cells 26%
  • Regeneration 19%
  • Stem Cells 17%

• Inactivation Mechanisms of Microvascular Hyperpermeability

  Duran, W.

  2/1/21 → 1/31/22

  Project: Research project

  • vasodilator-stimulated phosphoprotein 100%
  • Cell Membrane 47%
  • Preliminary Data 20%
  • Cytosol 17%
  • Endothelial Cells 13%

• PROTECTING NEURAL CIRCUITRY AFTER INJURY

  Townes-Anderson, E.

  Congressionally Directed Medical Research Programs (CDMRP)

  9/30/19 → 9/29/21

  Project: Research project

  • Lim Kinases 100%
  • Retinal Detachment 92%
  • Eye 75%
  • Retina 73%
  • Wounds and Injuries 67%

• Molecular mechanism of TRPV1 activation

  Rohacs, T., Carnevale, V. & Rohacs, T.

  National Institute of General Medical Sciences

  9/10/19 → 7/31/22

  Project: Research project

  • Nociceptive 100%
  • Asparagine Residue 83%
  • Pore 78%
  • Conformational Transition 66%
  • Site-Directed Mutagenesis 62%

• Mechanisms by which phosphorylation and protein partners regulate Cx45

  Harris, A., SORGEN, P., SORGEN, P. & Harris, A.

  9/10/19 → 6/30/22

  Project: Research project

  • Connexin 43 100%
  • Gap Junctions 56%
  • Connexins 40%
  • Phosphorylation 33%
  • Heart 31%

• THE ROLE OF LATERAL HYPOTHALAMUS OREXIN GLUCOSE-INHIBITED NEURONS IN BINGE-EATING DISORDER

  Routh, V.

  Congressionally Directed Medical Research Programs (CDMRP)

  8/15/19 → 8/14/22

  Project: Research project

  • Orexins 100%
  • Binge-Eating Disorder 75%
  • Lateral Hypothalamic Area 71%
  • Bulimia 55%
  • Glucose 52%

• Structural Basis of Electrical Signaling in the Heart and the Nervous System

  Contreras, J.

  8/1/19 → 7/31/20

  Project: Research project

  • ion 82%
  • biophysics 62%
  • membrane 58%
  • human disease 58%
  • minority 50%

• Regulatory Mechanisms of Microvascular Permeability

  Duran, W.

  National Heart, Lung, and Blood Institute

  9/21/18 → 1/31/20

  Project: Research project

  • vasodilator-stimulated phosphoprotein 100%
  • Capillary Permeability 45%
  • Nitrosation 43%
  • Cell Membrane 33%
  • Endothelial Cells 20%

• Mucosal modulation by LGG and R. gnavus specific tryptophan metabolites

  Ferraris, R., Gao, N., Ferraris, R. & Gao, N.

  National Center for Complementary and Integrative Health

  9/20/18 → 8/31/22

  Project: Research project

  • Lactobacillus rhamnosus 100%
  • Aryl Hydrocarbon Receptors 88%
  • Tryptophan 81%
  • Probiotics 26%
  • Metabolomics 20%

• Neural circuitry for state-dependent control of cortical auditory processing and perception

  Carcea, I.

  National Institute of Mental Health

  9/7/18 → 7/31/20

  Project: Research project

  • Auditory Cortex 100%
  • Auditory Perception 95%
  • Frontal Lobe 63%
  • Optogenetics 44%
  • Brain 24%

• Connexin 43: a new player in Duchenne muscular dystrophy associated cardiomyopathy

  Contreras, J., Fraidenraich, D., Shirokova, N., Contreras, J. & Fraidenraich, D.

  National Heart, Lung, and Blood Institute

  9/1/18 → 6/30/22

  Project: Research project

  • Connexin 43 100%
  • Duchenne Muscular Dystrophy 80%
  • Cardiomyopathies 60%
  • Dystrophin 22%
  • Heart 11%

• PDGF Responsive Progenitors of the Subventricular Zone

  Levison, S.

  National Institute of Neurological Disorders and Stroke

  7/1/18 → 6/30/21

  Project: Research project

  • Platelet-Derived Growth Factor 100%
  • Neuroglia 53%
  • Neural Stem Cells 45%
  • Nervous System Trauma 24%
  • Fibroblast Growth Factors 24%

• Studying Pathogenic Mechanism of Hereditary Cerebral Amyloid Angiopathy

  Ahn, H. J. & Ahn, H. J.

  National Institute of Neurological Disorders and Stroke

  4/1/18 → 12/31/21

  Project: Research project

  • Familial Cerebral Amyloid Angiopathy 100%
  • Cerebral Amyloid Angiopathy 81%
  • Alzheimer Disease 22%
  • Blood Vessels 16%
  • Fibrin 16%

• Structure-guided optimization of an in vivo active small molecule antitubercular targeting KasA

  Freundlich, J. & Ekins, S.

  National Institute of Allergy and Infectious Diseases

  2/7/18 → 7/31/19

  Project: Research project

  • Tuberculosis 100%
  • Isoniazid 92%
  • Mycobacterium tuberculosis 78%
  • Multidrug-Resistant Tuberculosis 49%
  • Pharmaceutical Preparations 41%

• The role of mTOR signaling in oligodendrocyte differentiation and CNS myelination

  Wood, T., MacKlin, W., MacKlin, W. & Wood, T.

  National Institute of Neurological Disorders and Stroke

  9/30/17 → 7/31/22

  Project: Research project

  • Oligodendroglia 100%
  • Myelin Sheath 53%
  • integrin-linked kinase 39%
  • Spinal Cord 31%
  • Corpus Callosum 28%

• Multi-tier regulation of mitochondrial Nfs1 cysteine desulfurase

  Pain, D. & Dancis, A.

  National Institute of General Medical Sciences

  9/15/17 → 8/31/18

  Project: Research project

  • cysteine desulfurase 100%
  • GTP Phosphohydrolases 69%
  • persulfides 56%
  • Mitochondria 49%
  • Sulfur 47%

• Pathways that regulate basal and metastatic phenotypes in triple negative breast cancers

  Wood, T. & WOOD, T.

  National Cancer Institute

  1/1/17 → 12/31/21

  Project: Research project

  • Triple Negative Breast Neoplasms 100%
  • Phenotype 56%
  • Protein-Tyrosine Kinases 15%
  • Somatomedin Receptors 10%
  • Neoplasms 10%

• Role for Glucose-Inhibited Orexin Neurons in Weight Regain Following Dieting

  Beck, K. & Routh, V.

  National Institute of Diabetes and Digestive and Kidney Diseases

  7/1/16 → 6/30/20

  Project: Research project

  • Orexins 100%
  • Glucose 53%
  • Reward 46%
  • Neurons 45%
  • Weights and Measures 44%

• Novel cellular approach to study acute neuronal hyperexcitability in a traumatic brain injury model

  Berlin, J. & Pfister, B.

  National Institute of Neurological Disorders and Stroke

  7/1/16 → 6/30/19

  Project: Research project

  • Traumatic Brain Injury 100%
  • Neurons 71%
  • Seizures 52%
  • Wounds and Injuries 23%
  • Synaptic Transmission 18%

• Contribution of innate immune receptors to neurological dysfunction after traumatic brain injury: Mechanisms and therapeutic implications

  Santhakumar, V.

  7/1/16 → 3/31/22

  Project: Research project

  • Neurogenesis 100%
  • Toll-Like Receptor 4 97%
  • Traumatic Brain Injury 92%
  • Wounds and Injuries 32%
  • Matrix Metalloproteinase 9 30%

• Neural circuitry for state-dependent control of cortical auditory processing and perception

  Carcea, I.

  National Institute of Mental Health

  2/1/16 → 8/31/18

  Project: Research project

  • Auditory Cortex 100%
  • Auditory Perception 95%
  • Frontal Lobe 79%
  • Optogenetics 44%
  • Brain 24%

• PLASTICITY OF RENEWABLE EPITHELIA IN THE MAMMALIAN SMALL INTESTINE

  Ferraris, R.

  National Science Foundation (National Science Foundation (NSF))

  5/1/15 → 4/30/18

  Project: Research project

  • fructose 100%
  • stem cells 68%
  • small intestine 62%
  • plasticity 61%
  • transporters 59%

• NO signaling by a Soluble Guanylyl Cyclase -Thioredoxin transnitrosation complex

  Beuve, A., Li, H. & Li, H.

  National Institute of General Medical Sciences

  4/1/15 → 8/31/22

  Project: Research project

  • Soluble Guanylyl Cyclase 100%
  • Thioredoxins 97%
  • Nitrosation 81%
  • Nitric Oxide 71%
  • Cysteine 31%

• Mitochondria-cytoplasm interactions for cytosolic Fe-S cluster assembly

  Pain, D., Pain, D., Dancis, A., Dancis, A., Stemmler, T. L., Stemmler, T. L. & Pain, D.

  National Institute of General Medical Sciences

  7/1/14 → 2/28/22

  Project: Research project

  • Mitochondria 100%
  • Sulfur 87%
  • Cytoplasm 84%
  • Iron-Sulfur Proteins 59%
  • Transfer RNA 57%

• EAGER: A NOVEL FORM OF INTRANEURONAL MEMBRANE TRANSPORT

  Muresan, V.

  National Science Foundation (National Science Foundation (NSF))

  9/15/13 → 8/31/15

  Project: Research project

  • Synapses 100%
  • Neurons 50%
  • Membranes 40%
  • Water Sports 37%
  • Rivers 33%

• IGF-II and Insulin Receptors in Neural Stem Cells

  Levison, S. & Wood, T.

  National Institute of Neurological Disorders and Stroke

  9/15/13 → 2/28/17

  Project: Research project

  • Insulin-Like Growth Factor II 100%
  • IGF Type 2 Receptor 83%
  • Neural Stem Cells 74%
  • Insulin Receptor 72%
  • Adult Stem Cells 18%

• Development of a hepatoprotective strategy for preventing drug-induced liver inju

  Harris, A., KING, K. & PATEL, S.

  8/21/13 → 7/31/17

  Project: Research project

  • connexin 32 100%
  • Chemical and Drug Induced Liver Injury 65%
  • High-Throughput Screening Assays 35%
  • Gap Junctions 28%
  • Pharmaceutical Preparations 25%

• 2013, 2014 and 2015 Mammary Gland Biology Gordon Research Conference & Gordon Res

  Wood, T.

  6/3/13 → 5/31/14

  Project: Research project

  • breast neoplasms 100%
  • breasts 63%
  • biologists 56%
  • mammary glands 52%
  • stem cells 52%

• Annual meeting of the Organization for the Study of Sex Differences

  Beck, K.

  4/1/13 → 6/30/13

  Project: Research project

  • gender differences 100%
  • women's health 20%
  • autism 18%
  • audiovisual equipment 12%
  • dentistry 8%

• Regulation of Cx26 and Cx32 Channels by Cytosolic Interdomain Interactions

  Contreras, J., Harris, A., CONTRERAS, J. E. & HARRIS, A.

  National Institute of General Medical Sciences

  2/1/13 → 1/31/18

  Project: Research project

  • Connexins 100%
  • Mutation 22%
  • Connexin 43 21%
  • Protein Interaction Domains and Motifs 8%
  • Peptides 7%

• The role of mTOR signaling in oligodendrocyte differentiation and CNS myelination

  Wood, T., MacKlin, W., MacKlin, W. & WOOD, T.

  National Institute of Neurological Disorders and Stroke

  9/30/12 → 9/29/17

  Project: Research project

  • Oligodendroglia 100%
  • Remyelination 42%
  • Mechanistic Target of Rapamycin Complex 2 34%
  • Mechanistic Target of Rapamycin Complex 1 30%
  • Myelin Sheath 16%

• Malaria melatonin receptor signaling as a novel drug target

  Thomas, A.

  National Institute of Allergy and Infectious Diseases

  4/16/12 → 3/31/19

  Project: Research project

  • Melatonin Receptors 100%
  • Plasmodium 83%
  • Malaria 56%
  • Pharmaceutical Preparations 26%
  • Antimalarials 24%

• Neural Stability after Retinal Detachment

  Townes-Anderson, E., Whitehead, I. & Zarbin, M.

  National Eye Institute

  2/1/12 → 1/31/18

  Project: Research project

  • Retinal Detachment 100%
  • Axons 84%
  • Retina 55%
  • fasudil 48%
  • Retinal Neurons 43%

• Inhibitory Network Plasticity in Neurological Disease

  Santhakumar, V.

  9/30/11 → 4/30/22

  Project: Research project

  • Temporal Lobe Epilepsy 100%
  • Epilepsy 90%
  • Psychological Inhibition 87%
  • Seizures 82%
  • Dentate Gyrus 46%

• Gating and Regulation of Connexin Hemichannels

  Contreras, J.

  7/1/11 → 6/30/21

  Project: Research project

  • Connexin 43 100%
  • Connexins 33%
  • Nitric Oxide 27%
  • Nitrosation 21%
  • Cardiac Myocytes 12%

• Cardiac Dystrophy: Cellular Mechanisms

  Shirokova, N.

  National Heart, Lung, and Blood Institute

  4/1/11 → 2/29/16

  Project: Research project

  • calcium 100%
  • muscular diseases 91%
  • calcium signaling 84%
  • dystrophin 68%
  • muscular dystrophy 61%

• Regulation of the Intestinal Ca2+ Channels TRPV6

  Rohacs, T., Rohacs, T. & Carnevale, V.

  National Institute of General Medical Sciences

  4/1/11 → 1/31/20

  Project: Research project

  • Transient Receptor Potential Channels 100%
  • TRPV6 channel 78%
  • TRPV Cation Channels 77%
  • Phosphatidylinositols 43%
  • Calmodulin 35%

• CRNS: Model of hippocampal-amygdala interaction: Implications for PTSD

  Myers, C.

  National Institute on Alcohol Abuse and Alcoholism

  5/1/10 → 7/31/14

  Project: Research project

  • Post-Traumatic Stress Disorders 100%
  • Amygdala 61%
  • Alcoholism 34%
  • Anxiety Disorders 22%
  • Hippocampus 12%

• Glial Dysgenesis in the Injured Developing Brain

  Levison, S.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  5/1/10 → 2/28/14

  Project: Research project

  • Astrocytes 100%
  • Neuroglia 84%
  • Brain 53%
  • Hypoxia 52%
  • Ischemia 50%

• A novel ryanodine receptor in the hormonal regulation of hepatic metabolism

  Thomas, A.

  4/15/10 → 6/30/13

  Project: Research project

  • Ryanodine Receptor Calcium Release Channel 100%
  • Cyclic ADP-Ribose 36%
  • Hormones 32%
  • Hepatocytes 29%
  • Second Messenger Systems 25%

• Role of Cerebral Blood Flow in Nausea and Motion Sickness

  Serrador, J.

  2/5/10 → 11/30/12

  Project: Research project

  • Motion Sickness 100%
  • Brain 27%
  • Cerebrovascular Circulation 20%
  • Nausea 18%
  • Ventilation 6%

• Mitochondrial cysteine desulfurase

  Pain, D. & Dancis, A.

  National Institute of General Medical Sciences

  9/30/09 → 8/31/12

  Project: Research project

  • cysteine desulfurase 100%
  • persulfides 42%
  • Sulfur 35%
  • Mitochondria 31%
  • Transfer RNA 16%

• Role of neuropeptide Y-glucose inhibited (NPY-GI) neurons in cytokine-induced ano

  Routh, V.

  7/16/09 → 6/30/12

  Project: Research project

  • Neuropeptide Y 100%
  • Anorexia 58%
  • Glucose 54%
  • Cachexia 52%
  • Neurons 46%

• Hormonal regulation of glucose sensing neurons in health and diabetes

  Routh, V.

  National Institute of Diabetes and Digestive and Kidney Diseases

  7/1/09 → 6/30/11

  Project: Research project

  • Glucose 100%
  • Neurons 79%
  • Health 42%
  • Insulin 29%
  • Insulin Resistance 14%

• Hypoglycemia-induced NO in glucose sensing neurons and counterregulation

  Routh, V.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/20/09 → 3/31/15

  Project: Research project

  • Hypoglycemia 100%
  • Glucose 49%
  • Neurons 40%
  • Ventromedial Hypothalamic Nucleus 21%
  • Guanylate Cyclase-Coupled Receptors 12%

• Generation of monoclonal and polyclonal antibodies to neolacto-series ganglioside

  Ilyas, A.

  4/1/09 → 3/31/12

  Project: Research project

  • Gangliosides 100%
  • Peripheral Nervous System 27%
  • Antibody Affinity 18%
  • Anti-Idiotypic Antibodies 17%
  • Monoclonal Antibodies 14%

• Mitochondria and calcium signaling in skeletal muscle

  Shirokova, N.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/19/08 → 8/31/14

  Project: Research project

  • calcium signaling 100%
  • calcium 89%
  • mitochondria 58%
  • malignant hyperthermia 27%
  • muscular dystrophy 23%

• Inactivation of hyperpermeability after ischemia-reperfusion induced inflammation

  Duran, W.

  National Heart, Lung, and Blood Institute

  7/1/08 → 6/30/14

  Project: Research project

  • Reperfusion 100%
  • Ischemia 86%
  • Inflammation 60%
  • Striated Muscle 45%
  • Muscles 27%