Rutgers Office of Research Commercialization

Research Output

  • 3222 Citations
  • 30 h-Index
  • 94 Article
  • 2 Chapter
  • 2 Comment/debate
  • 2 Review article
2020

Acute feeding suppression and toxicity of raspberry ketone [4-(4-hydroxyphenyl)-2-butanone] in mice

Hao, L., Kshatriya, D., Li, X., Badrinath, A., Szmacinski, Z., Goedken, M. J., Polunas, M. & Bello, N. T., Sep 2020, In : Food and Chemical Toxicology. 143, 111512.

Research output: Contribution to journalArticle

Direct and Indirect Effects of Fibroblast Growth Factor (FGF) 15 and FGF19 on Liver Fibrosis Development

Schumacher, J. D., Kong, B., Wu, J., Rizzolo, D., Armstrong, L. E., Chow, M. D., Goedken, M., Lee, Y. H. & Guo, G. L., Feb 1 2020, In : Hepatology. 71, 2, p. 670-685 16 p.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access

Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard

Sunil, V. R., Vayas, K. N., Abramova, E. V., Rancourt, R., Cervelli, J. A., Malaviya, R., Goedken, M., Venosa, A., Gow, A. J., Laskin, J. D. & Laskin, D. L., Jan 15 2020, In : Toxicology and Applied Pharmacology. 387, 114798.

Research output: Contribution to journalArticle

1 Scopus citations

The COVID-19 pandemic and research shutdown: Staying safe and productive

Omary, M. B., Eswaraka, J., Kimball, S. D., Moghe, P., Panettieri, R. A. & Scotto, K. W., Jun 1 2020, In : Journal of Clinical Investigation. 130, 6, p. 2745-2748 4 p.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations

Vitamin D compounds and cancer stem cells in cancer prevention

Suh, N., Maehr, H. & Augeri, D., Jan 1 2020, Natural Products for Cancer Chemoprevention: Single Compounds and Combinations. Springer International Publishing, p. 143-159 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Bile Acid Homeostasis in a Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase Double Knockout Mouse Model

Rizzolo, D., Buckley, K., Kong, B., Zhan, L., Shen, J., Stofan, M., Brinker, A., Goedken, M., Buckley, B. & Guo, G. L., Jul 2019, In : Hepatology. 70, 1, p. 389-402 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis

Malekshah, O. M., Sarkar, S., Nomani, A., Patel, N., Javidian, P., Goedken, M., Polunas, M., Louro, P. & Hatefi, A., Oct 2019, In : Journal of Controlled Release. 311-312, p. 273-287 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Coencapsulation of ISCs and MSCs Enhances Viability and Function of both Cell Types for Improved Wound Healing

Aijaz, A., Teryek, M., Goedken, M., Polunas, M. & Olabisi, R. M., Oct 1 2019, In : Cellular and Molecular Bioengineering. 12, 5, p. 481-493 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Combinatorial therapy of zinc metallochaperones with mutant p53 reactivation and diminished copper binding

Zaman, S., Yu, X., Bencivenga, A. F., Blanden, A. R., Liu, Y., Withers, T., Na, B., Blayney, A. J., Gilleran, J., Boothman, D. A., Loh, S. N., Kimball, S. D. & Carpizo, D. R., Jan 1 2019, In : Molecular cancer therapeutics. 18, 8, p. 1355-1365 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Identification and quantification of gold engineered nanomaterials and impaired fluid transfer across the rat placenta via ex vivo perfusion

D'Errico, J. N., Doherty, C., Fournier, S. B., Renkel, N., Kallontzi, S., Goedken, M., Fabris, L., Buckley, B. & Stapleton, P. A., Sep 2019, In : Biomedicine and Pharmacotherapy. 117, 109148.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Inhibition of ER stress by 2-aminopurine treatment modulates cardiomyopathy in a murine chronic chagas disease model

Ayyappan, J. P., Lizardo, K., Wang, S., Yurkow, E. & Nagajyothi, J. F., 2019, In : Biomolecules and Therapeutics. 27, 4, p. 386-394 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity

Donepudi, A. C., Goedken, M. J., Schuetz, J. D. & E Manautou, J., 2019, In : Toxicology Reports. 6, p. 841-849 9 p.

Research output: Contribution to journalArticle

Open Access

Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity

Clarke, J. D., Dzierlenga, A., Arman, T., Toth, E., Li, H., Lynch, K. D., Tian, D. D., Goedken, M., Paine, M. F. & Cherrington, N., Apr 15 2019, In : Toxicon. 162, p. 1-8 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sub-chronic microcystin-LR liver toxicity in preexisting diet-induced nonalcoholic steatohepatitis in rats

Arman, T., Lynch, K. D., Montonye, M. L., Goedken, M. & Clarke, J. D., Jul 9 2019, In : Toxins. 11, 7, toxins11070398.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein

Nemoyer, R., Mondal, A., Vora, M., Langenfeld, E., Glover, D., Scott, M., Lairson, L., Rongo, C., Augeri, D. J., Peng, Y., Jabbour, S. K. & Langenfeld, J., Nov 19 2019, In : Cell Communication and Signaling. 17, 1, 150.

Research output: Contribution to journalArticle

Open Access

Therapeutic targeting of BRCA1 and TP53 mutant breast cancer through mutant p53 reactivation

Na, B., Yu, X., Withers, T., Gilleran, J., Yao, M., Foo, T. K., Chen, C., Moore, D., Lin, Y., Kimball, S. D., Xia, B., Ganesan, S. & Carpizo, D. R., Dec 1 2019, In : npj Breast Cancer. 5, 1, 14.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2018

Effect of World Trade Center Dust Exposure and Chronic Intermittent Hypoxia on Macrophage Matrix Metalloproteinase-12 Expression in Mice

Radbel, J., Le-Hoang, O., Vayas, K. N., Patel, K., Goedken, M., Sunil, V. R., Laskin, D. & Sunderram, J., Apr 1 2018, In : Annals of the American Thoracic Society. 15, 2, p. S125-S126

Research output: Contribution to journalArticle

Open Access

Gene-by-environment interaction of Bcrp-/- and methionine-and choline-deficient diet-induced nonalcoholic steatohepatitis alters SN-38 disposition

Toth, E. L., Li, H., Dzierlenga, A. L., Clarke, J. D., Vildhede, A., Goedken, M. & Cherrington, N. J., Nov 2018, In : Drug Metabolism and Disposition. 46, 11, p. 1478-1486 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Improved freeze drying efficiency by ice nucleation proteins with ice morphology modification

Jin, J., Yurkow, E. J., Adler, D. & Lee, T. C., Apr 2018, In : Food Research International. 106, p. 90-97 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Novel bone morphogenetic protein receptor inhibitor JL5 suppresses tumor cell survival signaling and induces regression of human lung cancer

Newman, J. H., Augeri, D. J., Nemoyer, R., Malhotra, J., Langenfeld, E., Chesson, C. B., Dobias, N. S., Lee, M. J., Tarabichi, S., Jhawar, S. R., Bommareddy, P. K., Marshall, SR., Sadimin, E. T., Kerrigan, J. E., Goedken, M., Minerowicz, C., Jabbour, S. K., Li, S., Carayannopolous, M. O., Zloza, A. & 1 others, Langenfeld, J., Jul 5 2018, In : Oncogene. 37, 27, p. 3672-3685 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Protective Role of Surfactant Protein-D Against Lung Injury and Oxidative Stress Induced by Nitrogen Mustard

Sunil, V. R., Vayas, K. N., Cervelli, J. A., Ebramova, E. V., Gow, A. J., Goedken, M., Malaviya, R., Laskin, J. D. & Laskin, D. L., Nov 1 2018, In : Toxicological sciences : an official journal of the Society of Toxicology. 166, 1, p. 108-122 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Zinc metallochaperones reactivate mutant p53 using an on/off switch mechanism: A new paradigm in cancer therapeutics

Yu, X., Kogan, S., Chen, Y., Tsang, A. T., Withers, T., Lin, H., Gilleran, J., Buckley, B., Moore, D., Bertino, J., Chan, C., Kimball, S., Loh, S. N. & Carpizo, D., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4505-4517 13 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017

A Novel Approach To Improve the Efficiency of Block Freeze Concentration Using Ice Nucleation Proteins with Altered Ice Morphology

Jin, J., Yurkow, E. J., Adler, D. & Lee, T. C., Mar 22 2017, In : Journal of agricultural and food chemistry. 65, 11, p. 2373-2382 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s)

Garbuzenko, O. B., Ivanova, V., Kholodovych, V., Reimer, D. C., Reuhl, K. R., Yurkow, E., Adler, D. & Minko, T., Aug 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 6, p. 1983-1992 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice

Li, H., Clarke, J. D., Dzierlenga, A. L., Bear, J., Goedken, M. J. & Cherrington, N. J., Feb 1 2017, In : Journal of Biochemical and Molecular Toxicology. 31, 2, e21840.

Research output: Contribution to journalArticle

10 Scopus citations

Synthesis and Characterization of Novel BMI1 Inhibitors Targeting Cellular Self-Renewal in Hepatocellular Carcinoma

Bartucci, M., Hussein, M. S., Huselid, E., Flaherty, K., Patrizii, M., Laddha, S. V., Kui, C., Bigos, R. A., Gilleran, J. A., El Ansary, M. M. S., Awad, M. A. M., Kimball, S., Augeri, D. & Sabaawy, H., Aug 1 2017, In : Targeted Oncology. 12, 4, p. 449-462 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis

Schumacher, J. D., Kong, B., Pan, Y., Zhan, L., Sun, R., Aa, J., Rizzolo, D., Richardson, J. R., Chen, A., Goedken, M., Aleksunes, L. M., Laskin, D. L. & Guo, G. L., Sep 1 2017, In : Toxicology and Applied Pharmacology. 330, p. 1-8 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Thiosemicarbazones functioning as zinc metallochaperones to reactivate mutant p53

Yu, X., Blanden, A., Tsang, A. T., Zaman, S., Liu, Y., Gilleran, J., Bencivenga, A. F., Kimball, S. D., Loh, S. N. & Carpizo, D. R., Jun 2017, In : Molecular pharmacology. 91, 6, p. 567-575 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

Effect of nonalcoholic steatohepatitis on renal filtration and secretion of adefovir

Laho, T., Clarke, J. D., Dzierlenga, A. L., Li, H., Klein, D. M., Goedken, M., Micuda, S. & Cherrington, N. J., Sep 1 2016, In : Biochemical Pharmacology. 115, p. 144-151 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Enhanced hepatotoxicity by acetaminophen in Vanin-knockout mice is associated with deficient proliferative and immune responses

Ferreira, D. W., Goedken, M. J., Rommelaere, S., Chasson, L., Galland, F., Naquet, P. & Manautou, J. E., Apr 1 2016, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 4, p. 662-669 8 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death

Augeri, D. J., Langenfeld, E., Castle, M., Gilleran, J. A. & Langenfeld, J., Apr 6 2016, In : Molecular Cancer. 15, 1, 27.

Research output: Contribution to journalArticle

20 Scopus citations
2015

Erratum: Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore (Molecular Pharmacology (2015) 87 (825-831))

Blanden, R., Yu, X., Aaron, J. W., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N., Dec 1 2015, In : Molecular pharmacology. 88, 6, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Erratum:N-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent(Journal of Medicinal Chemistry (2004) 47 (1719-1728) DOI: 10.1021/jm0305568)

Misra, R. N., Xiao, H. Y., Kim, K. S., Lu, S., Han, W. C., Barbosa, S. A., Hunt, J. T., Rawlins, D. B., Shan, W., Ahmed, S. Z., Qian, L., Chen, B. C., Zhao, R., Bednarz, M. S., Kellar, K. A., Mulheron, J. G., Batorsky, R., Roongta, U., Kamath, A., Marathe, P. & 7 others, Ranadive, S. A., Sack, J. S., Tokarski, J. S., Pavletich, N. P., Lee, F. Y. F., Webster, K. R. & Kimball, S. D., Sep 24 2015, In : Journal of medicinal chemistry. 58, 18, 1 p.

Research output: Contribution to journalComment/debate

Interactions between nuclear receptor SHP and FOXA1 maintain oscillatory homocysteine homeostasis in mice

Tsuchiya, H., Da Costa, K. A., Lee, S., Renga, B., Jaeschke, H., Yang, Z., Orena, S. J., Goedken, M. J., Zhang, Y., Kong, B., Lebofsky, M., Rudraiah, S., Smalling, R., Guo, G., Fiorucci, S., Zeisel, S. H. & Wang, L., May 1 2015, In : Gastroenterology. 148, 5, p. 1012-1023.e14

Research output: Contribution to journalArticle

29 Scopus citations

Mechanism of altered metformin distribution in nonalcoholic steatohepatitis

Clarke, J. D., Dzierlenga, A. L., Nelson, N. R., Li, H., Werts, S., Goedken, M. J. & Cherrington, N. J., Sep 2015, In : Diabetes. 64, 9, p. 3305-3313 9 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Multidrug resistance-associated protein 3 plays an important role in protection against acute toxicity of diclofenac

Scialis, R. J., Csanaky, I. L., Goedken, M. J. & Manautou, J. E., Jul 1 2015, In : Drug Metabolism and Disposition. 43, 7, p. 944-950 7 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis

Canet, M. J., Hardwick, R. N., Lake, A. D., Dzierlenga, A. L., Clarke, J. D., Goedken, M. J. & Cherrington, N. J., Jan 1 2015, In : Drug Metabolism and Disposition. 43, 2, p. 266-272 7 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice

Ghanem, C. I., Rudraiah, S., Bataille, A. M., Vigo, M. B., Goedken, M. J. & Manautou, J. E., Apr 1 2015, In : Biochemical Pharmacology. 94, 3, p. 203-211 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore

Blanden, A. R., Yu, X., Wolfe, A. J., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N., May 1 2015, In : Molecular pharmacology. 87, 5, p. 825-831 7 p.

Research output: Contribution to journalArticle

38 Scopus citations
2014

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity

Salojin, K. V., Hamman, B. D., Chang, W. C., Jhaver, K. G., Al-Shami, A., Crisostomo, J., Wilkins, C., Digeorge-Foushee, A. M., Allen, J., Patel, N., Gopinathan, S., Zhou, J., Nouraldeen, A., Jessop, T. C., Bagdanoff, J. T., Augeri, D. J., Read, R., Vogel, P., Swaffield, J., Wilson, A. & 5 others, Platt, K. A., Carson, K. G., Main, A., Zambrowicz, B. P. & Oravecz, T., May 22 2014, In : PloS one. 9, 5, e98151.

Research output: Contribution to journalArticle

30 Scopus citations

Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis

Hardwick, R. N., Clarke, J. D., Lake, A. D., Canet, M. J., Anumol, T., Street, S. M., Merrell, M. D., Goedken, M. J., Snyder, S. A. & Cherrington, N. J., Nov 1 2014, In : Toxicological Sciences. 142, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Is nuclear factor erythroid 2-Related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in Mice?

Rohrer, P. R., Rudraiah, S., Goedken, M. J. & Manautou, J. E., Oct 1 2014, In : Drug Metabolism and Disposition. 42, 10, p. 1663-1674 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells

Wen, X., Gibson, C. J., Yang, I., Buckley, B., Goedken, M. J., Richardson, J. R. & Aleksunes, L. M., Oct 1 2014, In : Toxicological Sciences. 141, 2, p. 475-483 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism

Yu, X., Blanden, A. R., Narayanan, S., Jayakumar, L., Lubin, D., Augeri, D., David Kimball, S., Loh, S. N. & Carpizo, D. R., 2014, In : Oncotarget. 5, 19, p. 8879-8892 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Synergistic interaction between genetics and disease on pravastatin disposition

Clarke, J. D., Hardwick, R. N., Lake, A. D., Lickteig, A. J., Goedken, M. J., Klaassen, C. D. & Cherrington, N. J., Jul 2014, In : Journal of Hepatology. 61, 1, p. 139-147 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat

Kyriakides, M., Hardwick, R. N., Jin, Z., Goedken, M. J., Holmes, E., Cherrington, N. J. & Coen, M., Nov 1 2014, In : Toxicological Sciences. 142, 1, p. 105-116 12 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes

Rudraiah, S., Rohrer, P. R., Gurevich, I., Goedken, M. J., Rasmussen, T., Hines, R. N. & Manautou, J. E., Sep 12 2014, In : Toxicological Sciences. 141, 1, p. 263-277 15 p., kfu124.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-Null mice

Wen, X., Buckley, B., McCandlish, E., Goedken, M. J., Syed, S., Pelis, R., Manautou, J. E. & Aleksunes, L. M., Jan 1 2014, In : American Journal of Pathology. 184, 5, p. 1299-1308 10 p.

Research output: Contribution to journalArticle

28 Scopus citations
2013

Pregnancy represses induction of efflux transporters in livers of type i diabetic mice

Aleksunes, L. M., Xu, J., Lin, E., Wen, X., Goedken, M. J. & Slitt, A. L., Sep 2013, In : Pharmaceutical research. 30, 9, p. 2209-2220 12 p.

Research output: Contribution to journalArticle

7 Scopus citations