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Fingerprint Dive into the research topics where Bing Xia is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Homologous Recombination Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Fanconi Anemia Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Escherichia coli Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Projects 2009 2020

Autophagy
Breast Neoplasms
Oxidative Stress
Homologous Recombination
Carcinogenesis
DNA Damage
Breast Neoplasms
Neoplasms
Cell Cycle Checkpoints
Tumor Suppressor Proteins

Research Output 1998 2019

  • 4580 Citations
  • 28 h-Index
  • 50 Article
  • 3 Review article
  • 2 Comment/debate
  • 2 Letter
7 Citations (Scopus)

BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation

Zong, D., Adam, S., Wang, Y., Sasanuma, H., Callén, E., Murga, M., Day, A., Kruhlak, M. J., Wong, N., Munro, M., Ray Chaudhuri, A., Karim, B., Xia, B., Takeda, S., Johnson, N., Durocher, D. & Nussenzweig, A., Mar 21 2019, In : Molecular cell. 73, 6, p. 1267-1281.e7

Research output: Contribution to journalArticle

Haploinsufficiency
Ubiquitination
Homologous Recombination
Chromatin
Genomic Instability

Functional characterization of 84 PALB2 variants of uncertain significance

Wiltshire, T., Ducy, M., Foo, T. K., Hu, C., Lee, K. Y., Belur Nagaraj, A., Rodrigue, A., Gomes, T. T., Simard, J., Monteiro, A. N. A., Xia, B., Carvalho, M. A., Masson, J. Y. & Couch, F. J., Jan 1 2019, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journalArticle

DNA Repair
Genetic Testing
Pancreatic Neoplasms
Cisplatin
DNA Damage
1 Citation (Scopus)

Homologous recombination DNA repair defects in PALB2-associated breast cancers

KConFab Investigators, Dec 1 2019, In : npj Breast Cancer. 5, 1, 23.

Research output: Contribution to journalArticle

Open Access
Recombinational DNA Repair
Breast Neoplasms
Loss of Heterozygosity
Homologous Recombination
Alleles
2 Citations (Scopus)

PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response

Simhadri, S., Vincelli, G., Huo, Y., Misenko, S., Foo, T. K., Ahlskog, J., Sørensen, C. S., Oakley, G. G., Ganesan, S., Bunting, S. & Xia, B., Mar 7 2019, In : Oncogene. 38, 10, p. 1585-1596 12 p.

Research output: Contribution to journalArticle

Maintenance
Homologous Recombination
DNA Damage
M Phase Cell Cycle Checkpoints
Tumor Suppressor Proteins
2 Citations (Scopus)

Antiparallel Coiled-Coil Interactions Mediate the Homodimerization of the DNA Damage-Repair Protein PALB2

Song, F., Li, M., Liu, G., Swapna, G. V. T., Daigham, N. S., Xia, B., Montelione, G. T. & Bunting, S. F., Nov 27 2018, In : Biochemistry. 57, 47, p. 6581-6591 11 p.

Research output: Contribution to journalArticle

Homologous Recombination
DNA Repair
DNA Damage
Repair
Double-Stranded DNA Breaks