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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Neoplasms Medicine & Life Sciences
Autophagy Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Neuroendocrine Tumors Medicine & Life Sciences
Germ-Line Mutation Medicine & Life Sciences
Tumors Chemical Compounds
Carcinogenesis Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Projects 2016 2019

Genetic Research
Epigenomics
Neoplasms
Acute Myeloid Leukemia
Therapeutics

Research Output 2000 2018

  • 1104 Citations
  • 16 h-Index
  • 23 Article
  • 3 Review article
  • 1 Conference contribution
1 Citation (Scopus)

ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup

Chan, C., Laddha, S. V., Lewis, P. W., Koletsky, M. S., Robzyk, K., Da Silva, E., Torres, P. J., Untch, B. R., Li, J., Bose, P., Chan, T. A., Klimstra, D. S., Allis, C. D. & Tang, L. H., Dec 1 2018, In : Nature communications. 9, 1, 4158.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Neuroendocrine Tumors
subgroups
Tumors
tumors
17 Citations (Scopus)

Why are there hotspot mutations in the TP53 gene in human cancers?

Baugh, E. H., Ke, H., Levine, A. J., Bonneau, R. A. & Chan, C., Jan 1 2018, In : Cell Death and Differentiation. 25, 1, p. 154-160 7 p.

Research output: Contribution to journalReview article

p53 Genes
Mutation
Mutant Proteins
Alleles
Neoplasms
4 Citations (Scopus)

Zinc metallochaperones reactivate mutant p53 using an on/off switch mechanism: A new paradigm in cancer therapeutics

Yu, X., Kogan, S., Chen, Y., Tsang, A. T., Withers, T., Lin, H., Gilleran, J., Buckley, B., Moore, D., Bertino, J., Chan, C., Kimball, S., Loh, S. N. & Carpizo, D., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4505-4517 13 p.

Research output: Contribution to journalArticle

Metallochaperones
Zinc
Neoplasms
Therapeutics
Pharmacokinetics

Prevalence and penetrance of Li-Fraumeni cancer predisposition syndrome

Chan, C., Feb 1 2017, In : Current Opinion in Systems Biology. 1, p. 48-53 6 p.

Research output: Contribution to journalReview article

Penetrance
Li-Fraumeni Syndrome
Cancer
Germ-Line Mutation
Genes
55 Citations (Scopus)

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells

Guo, Y., Teng, X., Laddha, S. V., Ma, S., Van Nostrand, S. C., Yang, Y., Khor, S., Chan, C., Rabinowitz, J. D. & White, E., Aug 1 2016, In : Genes and Development. 30, 15, p. 1704-1717 14 p.

Research output: Contribution to journalArticle

Autophagy
Lung Neoplasms
Nucleotides
Starvation
Mitochondria