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Fingerprint Dive into the research topics where Chang Chan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Neoplasms Medicine & Life Sciences
Autophagy Medicine & Life Sciences
Neuroendocrine Tumors Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Germ-Line Mutation Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Mutation Medicine & Life Sciences
Multiple Endocrine Neoplasia Type 1 Medicine & Life Sciences

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Projects 2016 2019

Genetic Research
Epigenomics
Neoplasms
Acute Myeloid Leukemia
Therapeutics

Research Output 2000 2019

  • 1234 Citations
  • 16 h-Index
  • 25 Article
  • 3 Review article
  • 1 Conference contribution

Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression

Choi, S., Wang, D., Chen, X., Tang, L. H., Verma, A., Chen, Z., Kim, B. J., Selesner, L., Robzyk, K., Zhang, G., Pang, S., Han, T., Chan, C., Fahey, T. J., Elemento, O. & Du, Y. C. N., May 9 2019, In : Molecular Cancer. 18, 1, 92.

Research output: Contribution to journalArticle

Open Access
Hyaluronic Acid
Protein Isoforms
Neoplasms
Neoplasm Metastasis
Primitive Neuroectodermal Tumors

Integrative genomic characterization identifies molecular subtypes of lung carcinoids

Laddha, S. V., Da Silva, E. M., Robzyk, K., Untch, B. R., Ke, H., Rekhtman, N., Poirier, J. T., Travis, W. D., Tang, L. H. & Chan, C., Sep 1 2019, In : Cancer Research. 79, 17, p. 4339-4347 9 p.

Research output: Contribution to journalArticle

Carcinoid Tumor
Multiple Endocrine Neoplasia Type 1
DNA Methylation
Lung
Histone Code
6 Citations (Scopus)

ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup

Chan, C., Laddha, S. V., Lewis, P. W., Koletsky, M. S., Robzyk, K., Da Silva, E., Torres, P. J., Untch, B. R., Li, J., Bose, P., Chan, T. A., Klimstra, D. S., Allis, C. D. & Tang, L. H., Dec 1 2018, In : Nature communications. 9, 1, 4158.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Neuroendocrine Tumors
subgroups
Tumors
tumors
32 Citations (Scopus)

Why are there hotspot mutations in the TP53 gene in human cancers?

Baugh, E. H., Ke, H., Levine, A. J., Bonneau, R. A. & Chan, C., Jan 1 2018, In : Cell Death and Differentiation. 25, 1, p. 154-160 7 p.

Research output: Contribution to journalReview article

p53 Genes
Mutation
Mutant Proteins
Alleles
Neoplasms
7 Citations (Scopus)

Zinc metallochaperones reactivate mutant p53 using an on/off switch mechanism: A new paradigm in cancer therapeutics

Yu, X., Kogan, S., Chen, Y., Tsang, A. T., Withers, T., Lin, H., Gilleran, J., Buckley, B., Moore, D., Bertino, J., Chan, C., Kimball, S., Loh, S. N. & Carpizo, D., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4505-4517 13 p.

Research output: Contribution to journalArticle

Metallochaperones
Zinc
Neoplasms
Therapeutics
Pharmacokinetics