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Research Output 1974 2019

2019
3 Citations (Scopus)

Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

Kim, H., Xu, R., Padmashri, R., Dunaevsky, A., Liu, Y., Dreyfus, C. F. & Jiang, P., May 14 2019, In : Stem Cell Reports. 12, 5, p. 890-905 16 p.

Research output: Contribution to journalArticle

Open Access
Organoids
Pluripotent Stem Cells
Stem cells
Prosencephalon
Brain
2017
10 Citations (Scopus)

Strain differences in cuprizone induced demyelination

Yu, Q., Hui, R., Park, J., Huang, Y., Kusnecov, A. W., Dreyfus, C. F. & Zhou, R., Nov 3 2017, In : Cell and Bioscience. 7, 1, 59.

Research output: Contribution to journalArticle

Cuprizone
Demyelinating Diseases
Inbred C57BL Mouse
Corpus Callosum
Oligodendroglia
2016
12 Citations (Scopus)

The role of growth factors as a therapeutic approach to demyelinating disease

Huang, Y. & Dreyfus, C., Sep 1 2016, In : Experimental Neurology. 283, p. 531-540 10 p.

Research output: Contribution to journalReview article

Demyelinating Diseases
Intercellular Signaling Peptides and Proteins
Oligodendroglia
Neurodegenerative Diseases
Multiple Sclerosis
4 Citations (Scopus)

Valproic acid exposure during early postnatal gliogenesis leads to autistic-like behaviors in rats

Mony, T. J., Lee, J. W., Dreyfus, C., DiCicco-Bloom, E. & Lee, H. J., Nov 2016, In : Clinical Psychopharmacology and Neuroscience. 14, 4, p. 338-344 7 p.

Research output: Contribution to journalArticle

Valproic Acid
Interpersonal Relations
Neuroglia
Control Groups
10 Citations (Scopus)

Valproic acid stimulates proliferation of glial precursors during cortical gliogenesis in developing rat

Lee, H. J., Dreyfus, C. & Dicicco-Bloom, E., Jul 1 2016, In : Developmental Neurobiology. 76, 7, p. 780-798 19 p.

Research output: Contribution to journalArticle

Valproic Acid
Neuroglia
Astrocytes
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
2015
28 Citations (Scopus)

Brain-derived neurotrophic factor deficiency restricts proliferation of oligodendrocyte progenitors following cuprizone-induced demyelination

Tsiperson, V., Huang, Y., Bagayogo, I., Song, Y., VonDran, M. W., DiCicco-Bloom, E. & Dreyfus, C. F., Jan 1 2015, In : ASN neuro. 7, 1

Research output: Contribution to journalArticle

Cuprizone
Brain-Derived Neurotrophic Factor
Oligodendroglia
Demyelinating Diseases
Stem Cells
22 Citations (Scopus)

Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage

Liu, J., Tian, D., Murugan, M., Eyo, U. B., Dreyfus, C., Wang, W. & Wu, L-J., Oct 1 2015, In : Journal of neurochemistry. 135, 2, p. 347-356 10 p.

Research output: Contribution to journalArticle

Cuprizone
Demyelinating Diseases
Protons
Reactive Oxygen Species
NADPH Oxidase
2014
86 Citations (Scopus)

Astrocyte-Derived BDNF supports myelin protein synthesis after cuprizone-induced demyelination

Fulmer, C. G., VonDran, M. W., Stillman, A. A., Huang, Y., Hempstead, B. L. & Dreyfus, C. F., Jan 1 2014, In : Journal of Neuroscience. 34, 24, p. 8186-8196 11 p.

Research output: Contribution to journalArticle

Cuprizone
Myelin Proteins
Brain-Derived Neurotrophic Factor
Demyelinating Diseases
Astrocytes
2013
1 Citation (Scopus)

Culturing astrocytes from postnatal rats

Huang, Y. & Dreyfus, C. F., Sep 4 2013, Neural Development: Methods and Protocols. p. 71-80 10 p. (Methods in Molecular Biology; vol. 1018).

Research output: Chapter in Book/Report/Conference proceedingChapter

Astrocytes
1 Citation (Scopus)

Culturing oligodendrocyte lineage cells from neonatal rats

Fulmer, C. G. & Dreyfus, C. F., Sep 4 2013, Neural Development: Methods and Protocols. p. 81-91 11 p. (Methods in Molecular Biology; vol. 1018).

Research output: Chapter in Book/Report/Conference proceedingChapter

Oligodendroglia
Cell Culture Techniques
2012

Introduction to the special issue in honor of Ira B. Black

Chao, M. V. & Dreyfus, C. F., Jun 1 2012, In : Developmental Neurobiology. 72, 6, p. 753-754 2 p.

Research output: Contribution to journalEditorial

21st Century History
20th Century History
Neurobiology
2011
70 Citations (Scopus)

Levels of BDNF impact oligodendrocyte lineage cells following a cuprizone lesion

Vondran, M. W., Singh, H., Honeywell, J. Z. & Dreyfus, C. F., Oct 5 2011, In : Journal of Neuroscience. 31, 40, p. 14182-14190 9 p.

Research output: Contribution to journalArticle

Cuprizone
Brain-Derived Neurotrophic Factor
Oligodendroglia
Myelin Proteins
Corpus Callosum
2010
69 Citations (Scopus)

BDNF +/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain

Vondran, M. W., Clinton-Luke, P., Honeywell, J. Z. & Dreyfus, C. F., May 1 2010, In : Glia. 58, 7, p. 848-856 9 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Oligodendroglia
Stem Cells
trkB Receptor
Basal Forebrain
2009
70 Citations (Scopus)

Brain-derived neurotrophic factor effects on oligodendrocyte progenitors of the basal forebrain are mediated through TrkB and the MAP kinase pathway

Van't Veer, A., Du, Y., Fischer, T. Z., Boetig, D. R., Wood, M. R. & Dreyfus, C., Mar 31 2009, In : Journal of Neuroscience Research. 87, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Oligodendroglia
Mitogen-Activated Protein Kinases
Phosphotransferases
Stem Cells
29 Citations (Scopus)

Regulated release of BDNF by cortical oligodendrocytes is mediated through metabotropic glutamate receptors and the PLC pathway

Bagayogo, I. P. & Dreyfus, C. F., Dec 1 2009, In : ASN neuro. 1, 1, p. 1-12 12 p., e00001.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Brain-Derived Neurotrophic Factor
Oligodendroglia
Type C Phospholipases
Neurons
1 Citation (Scopus)

Release of trophic factors and immune molecules from astrocytes

Jean, Y. Y., Bagayogo, I. P. & Dreyfus, C., Jan 1 2009, Astrocytes in (Patho)Physiology of the Nervous System. Springer US, p. 351-381 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunologic Factors
Astrocytes
Poisons
Chemokines
Neurons
2008
28 Citations (Scopus)
Ephrin-A5
Growth Cones
Signal Transduction
Eph Family Receptors
EphA1 Receptor
8 Citations (Scopus)

Effects of behaviorally active ACTH (4-10) analogue - Semax on rat basal forebrain cholinergic neurons

Grivennikov, I. A., Dolotov, O. V., Zolotarev, Y. A., Andreeva, L. A., Myasoedov, N. F., Leacher, L., Black, I. B. & Dreyfus, C. F., May 12 2008, In : Restorative neurology and neuroscience. 26, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

ACTH (4-10)
Cholinergic Neurons
Choline O-Acetyltransferase
Neurons
Neuroglia
56 Citations (Scopus)

Glutamate elicits release of BDNF from basal forebrain astrocytes in a process dependent on metabotropic receptors and the PLC pathway

Jean, Y. Y., Lercher, L. D. & Dreyfus, C. F., Feb 1 2008, In : Neuron Glia Biology. 4, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Astrocytes
Glutamic Acid
Cholinergic Neurons
Metabotropic Glutamate Receptors
2006
44 Citations (Scopus)

Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes

Du, Y., Fischer, T. Z., Clinton-Luke, P., Lercher, L. D. & Dreyfus, C. F., Feb 1 2006, In : Molecular and Cellular Neuroscience. 31, 2, p. 366-375 10 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Oligodendroglia
Nerve Growth Factors
Neurotrophin 3
Myelin Basic Protein
55 Citations (Scopus)
Brain-Derived Neurotrophic Factor
Oligodendroglia
Mitogen-Activated Protein Kinases
Phosphatidylinositol 3-Kinase
Type C Phospholipases
2004
54 Citations (Scopus)

Differential Regulation of Neurotrophin Expression in Basal Forebrain Astrocytes by Neuronal Signals

Wu, H., Friedman, W. & Dreyfus, C., Apr 1 2004, In : Journal of Neuroscience Research. 76, 1, p. 76-85 10 p.

Research output: Contribution to journalArticle

Nerve Growth Factors
Astrocytes
Brain-Derived Neurotrophic Factor
Neurotrophin 3
Nerve Growth Factor
2003
77 Citations (Scopus)

Regionally specific effects of BDNF on oligodendrocytes

Du, Y., Fischer, T. Z., Lee, L. N., Lercher, L. D. & Dreyfus, C. F., Sep 22 2003, In : Developmental Neuroscience. 25, 2-4, p. 116-126 11 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Oligodendroglia
Myelin Basic Protein
Nerve Growth Factor
trkB Receptor
94 Citations (Scopus)

The trophic role of oligodendrocytes in the basal forebrain

Dai, X., Lercher, L. D., Clinton, P. M., Du, Y., Livingston, D. L., Vieira, C., Yang, L., Shen, M. M. & Dreyfus, C. F., Jul 1 2003, In : Journal of Neuroscience. 23, 13, p. 5846-5853 8 p.

Research output: Contribution to journalArticle

Oligodendroglia
Neurotrophin 3
Brain-Derived Neurotrophic Factor
Nerve Growth Factors
Conditioned Culture Medium
2002
79 Citations (Scopus)

Brain-derived neurotrophic factor: A novel human ovarian follicular protein

Seifer, D. B., Feng, B., Shelden, R. M., Chen, S. & Dreyfus, C., Jan 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 2, p. 655-659 5 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Oocytes
Proteins
Nerve Growth Factors
Neurology
34 Citations (Scopus)

Neurotrophin-4/5 and neurotrophin-3 are present within the human ovarian follicle but appear to have different paracrine/autocrine functions

Seifer, D. B., Feng, B., Shelden, R. M., Chen, S. & Dreyfus, C., Oct 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 10, p. 4569-4571 3 p.

Research output: Contribution to journalArticle

Neurotrophin 3
Ovarian Follicle
Oocytes
Brain-Derived Neurotrophic Factor
Nerve Growth Factors
175 Citations (Scopus)

Oligodendrocytes as providers of growth factors

Du, Y. & Dreyfus, C., Jun 15 2002, In : Journal of Neuroscience Research. 68, 6, p. 647-654 8 p.

Research output: Contribution to journalShort survey

Oligodendroglia
Intercellular Signaling Peptides and Proteins
Brain
Neurons
Neuroglia
2001
9 Citations (Scopus)

Differential regulation of p75 and trkB mRNA expression after depolarizing stimuli or BDNF treatment in basal forebrain neuron cultures

Elliott, R. C., Black, I. B. & Dreyfus, C., Oct 1 2001, In : Journal of Neuroscience Research. 66, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Neurons
Messenger RNA
trkB Receptor
Basal Forebrain
31 Citations (Scopus)

Neuronal signals regulate neurotrophin expression in oligodendrocytes of the basal forebrain

Dai, X., Qu, P. & Dreyfus, C. F., Jun 7 2001, In : Glia. 34, 3, p. 234-239 6 p.

Research output: Contribution to journalArticle

Neurotrophin 3
Brain-Derived Neurotrophic Factor
Oligodendroglia
Nerve Growth Factors
Nerve Growth Factor
2000
262 Citations (Scopus)

Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury

Dougherty, K. D., Dreyfus, C. F. & Black, I. B., Jan 1 2000, In : Neurobiology of Disease. 7, 6, p. 574-585 12 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Oligodendroglia
Microglia
Spinal Cord Injuries
Astrocytes
26 Citations (Scopus)

Multiple ephrins regulate hippocampal neurite outgrowth

Brownlee, H., Gao, P. P., Frisen, J., Dreyfus, C., Zhou, R. & Black, I. B., Sep 18 2000, In : Journal of Comparative Neurology. 425, 2, p. 315-322 8 p.

Research output: Contribution to journalArticle

Ephrins
Ephrin-A2
Neurites
Ephrin-A3
Ligands
1999
85 Citations (Scopus)

Ephrin-dependent growth and pruning of hippocampal axons

Gao, P. P., Yue, Y., Cerretti, D. P., Dreyfus, C. & Zhou, R., Mar 30 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 4073-4077 5 p.

Research output: Contribution to journalArticle

Ephrins
Neuronal Plasticity
Axons
Eph Family Receptors
Growth
69 Citations (Scopus)

Expression of neurotrophins in the adult spinal cord in vivo

Dreyfus, C. F., Dai, X., Lercher, L. D., Racey, B. R., Friedman, W. J. & Black, I. B., Apr 1 1999, In : Journal of Neuroscience Research. 56, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Nerve Growth Factors
Spinal Cord
Neurotrophin 3
Brain-Derived Neurotrophic Factor
Glial Fibrillary Acidic Protein
1998
20 Citations (Scopus)
Neurotrophin 3
Nerve Growth Factor Receptor
Purkinje Cells
Nerve Growth Factor
Dicarboxylic Acids
48 Citations (Scopus)

Neurotransmitters and neurotrophins collaborate to influence brain development

Dreyfus, C. F., Dec 1 1998, In : Perspectives on developmental neurobiology. 5, 4, p. 389-399 11 p.

Research output: Contribution to journalReview article

Nerve Growth Factors
Neurotransmitter Agents
Hippocampus
Locus Coeruleus
Brain

Transmitter plasticity in the developing brain

Aronson, S. L. & Dreyfus, C., Jan 1 1998, In : Mental Retardation and Developmental Disabilities Research Reviews. 4, 3, p. 150-156 7 p.

Research output: Contribution to journalReview article

Neurotransmitter Agents
Phenotype
Brain
Neurons
Neural Crest
39 Citations (Scopus)

Unilateral hippocampal lesions in newborn and adult rats: Effects on spatial memory and BDNF gene expression

Van Praag, H., Qu, P. M., Elliott, R. C., Wu, H., Dreyfus, C. F. & Black, I. B., Apr 1 1998, In : Behavioural Brain Research. 92, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Gene Expression
Water
Hippocampus
Parturition
1996
126 Citations (Scopus)

Regulation of topographic projection in the brain: Elf-1 in the hippocamposeptal system

Gao, P. P., Zhang, J. H., Yokoyama, M., Racey, B., Dreyfus, C. F., Black, I. B. & Zhou, R., Oct 1 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 11161-11166 6 p.

Research output: Contribution to journalArticle

EphA5 Receptor
Hippocampus
Eph Family Receptors
Neurons
Brain
54 Citations (Scopus)

Selective role for trkB neurotrophin receptors in rapid modulation of hippocampal synaptic transmission

Levine, E. S., Dreyfus, C., Black, I. B. & Plummer, M., Jun 1996, In : Molecular Brain Research. 38, 2, p. 300-303 4 p.

Research output: Contribution to journalArticle

trkB Receptor
Nerve Growth Factor Receptors
Synaptic Transmission
Hippocampus
Neurotrophin 3
14 Citations (Scopus)

The identification of a novel cDNA preferentially expressed in the olfactory-limbic system of the adult rat

Schaar, D., Varia, M. R., Elkabes, S., Ramakrishnan, L., Dreyfus, C. & Black, I. B., May 20 1996, In : Brain research. 721, 1-2, p. 217-228 12 p.

Research output: Contribution to journalArticle

Limbic System
Astrocytes
Complementary DNA
Substantia Nigra
Brain
14 Citations (Scopus)

Unilateral neonatal hippocampal lesion alters septal innervation and trophism of the entorhinal cortex

Van Praag, H., Alberch, J., Perez-Navarro, E., Wu, H., Qu, P. M., Black, I. B. & Dreyfus, C., Jan 1 1996, In : Experimental Neurology. 141, 1, p. 130-140 11 p.

Research output: Contribution to journalArticle

Entorhinal Cortex
Nerve Growth Factor
Memory Disorders
Cholinergic Fibers
Septum of Brain
1995
495 Citations (Scopus)
Brain-Derived Neurotrophic Factor
Receptor Protein-Tyrosine Kinases
Synaptic Transmission
Neurons
Hippocampus
19 Citations (Scopus)

Developmental regulation of neurotrophin-3 and trk c splice variants in optic nerve gliain vivo

Elkabes, S., Schaar, D., Dreyfus, C. & Black, I. B., Jun 1995, In : Neuroscience. 66, 4, p. 879-889 11 p.

Research output: Contribution to journalArticle

Neurotrophin 3
Nerve Growth Factors
Optic Nerve
Neuroglia
Messenger RNA
93 Citations (Scopus)

Differential effects of NGF and BDNF on voltage-gated calcium currents in embryonic basal forebrain neurons

Levine, E. S., Dreyfus, C., Black, I. B. & Plummer, M., Jan 1 1995, In : Journal of Neuroscience. 15, 4, p. 3084-3091 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Nerve Growth Factor
Calcium
Neurons
Nerve Growth Factors
142 Citations (Scopus)

Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells

Mount, H. T. J., Dean, D. O., Alberch, J., Dreyfus, C. & Black, I. B., Sep 26 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 20, p. 9092-9096 5 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Purkinje Cells
Cerebellum
Efferent Neurons
Cerebellar Cortex
1994
26 Citations (Scopus)

An improved method detects differential NGF and BDNF gene expression in response to depolarization in cultured hippocampal neurons

Elliott, R. C., Inturrisi, C. E., Black, I. B. & Dreyfus, C. F., Oct 1994, In : Molecular Brain Research. 26, 1-2, p. 81-88 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Nerve Growth Factor
Gene Expression
Neurons
Messenger RNA
16 Citations (Scopus)

Dissociation of motor hyperactivity and spatial memory deficits by selective hippocampal lesions in the neonatal rat

Van Praag, H., Dreyfus, C. & Black, I. B., Sep 1 1994, In : Journal of Cognitive Neuroscience. 6, 4, p. 321-331 11 p.

Research output: Contribution to journalArticle

Hyperkinesis
Memory Disorders
Hippocampus
Motor Activity
Adrenergic Neurons
55 Citations (Scopus)

Embryonic sensory development: Local expression of neurotrophin‐3 and target expression of nerve growth factor

Elkabes, S., Dreyfus, C., Schaar, D. & Black, I. B., Mar 8 1994, In : Journal of Comparative Neurology. 341, 2, p. 204-213 10 p.

Research output: Contribution to journalArticle

Sensory Ganglia
Nerve Growth Factor
Embryonic Development
Spinal Ganglia
Sensory Receptor Cells
43 Citations (Scopus)

Multiple astrocyte transcripts encode nigral trophic factors in rat and human

Schaar, D., Sieber, B. A., Sherwood, A. C., Dean, D., Mendoza, G., Ramakrishnan, L., Dreyfus, C. & Black, I. B., Dec 1994, In : Experimental Neurology. 130, 2, p. 387-393 7 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Substantia Nigra
Astrocytes
RNA
Dopaminergic Neurons