• 5942 Citations
  • 45 h-Index
1974 …2020

Research output per year

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Research Output

2020

Reactive Astrocytes as Therapeutic Targets for Brain Degenerative Diseases: Roles Played by Metabotropic Glutamate Receptors

Planas-Fontánez, T. M., Dreyfus, C. F. & Saitta, K. S., Mar 1 2020, In : Neurochemical Research. 45, 3, p. 541-550 10 p.

Research output: Contribution to journalArticle

Open Access
2019

Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

Kim, H., Xu, R., Padmashri, R., Dunaevsky, A., Liu, Y., Dreyfus, C. F. & Jiang, P., May 14 2019, In : Stem Cell Reports. 12, 5, p. 890-905 16 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2017

Strain differences in cuprizone induced demyelination

Yu, Q., Hui, R., Park, J., Huang, Y., Kusnecov, A. W., Dreyfus, C. F. & Zhou, R., Nov 3 2017, In : Cell and Bioscience. 7, 1, 59.

Research output: Contribution to journalArticle

11 Scopus citations
2016

The role of growth factors as a therapeutic approach to demyelinating disease

Huang, Y. & Dreyfus, C. F., Sep 1 2016, In : Experimental Neurology. 283, p. 531-540 10 p.

Research output: Contribution to journalReview article

14 Scopus citations

Valproic acid exposure during early postnatal gliogenesis leads to autistic-like behaviors in rats

Mony, T. J., Lee, J. W., Dreyfus, C., DiCicco-Bloom, E. & Lee, H. J., Nov 2016, In : Clinical Psychopharmacology and Neuroscience. 14, 4, p. 338-344 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Valproic acid stimulates proliferation of glial precursors during cortical gliogenesis in developing rat

Lee, H. J., Dreyfus, C. & DiCicco-Bloom, E., Jul 1 2016, In : Developmental Neurobiology. 76, 7, p. 780-798 19 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Brain-derived neurotrophic factor deficiency restricts proliferation of oligodendrocyte progenitors following cuprizone-induced demyelination

Tsiperson, V., Huang, Y., Bagayogo, I., Song, Y., VonDran, M. W., DiCicco-Bloom, E. & Dreyfus, C. F., Jan 1 2015, In : ASN neuro. 7, 1

Research output: Contribution to journalArticle

31 Scopus citations

Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage

Liu, J., Tian, D., Murugan, M., Eyo, U. B., Dreyfus, C., Wang, W. & Wu, L-J., Oct 1 2015, In : Journal of neurochemistry. 135, 2, p. 347-356 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2014

Astrocyte-Derived BDNF supports myelin protein synthesis after cuprizone-induced demyelination

Fulmer, C. G., VonDran, M. W., Stillman, A. A., Huang, Y., Hempstead, B. L. & Dreyfus, C. F., Jan 1 2014, In : Journal of Neuroscience. 34, 24, p. 8186-8196 11 p.

Research output: Contribution to journalArticle

91 Scopus citations
2013

Culturing astrocytes from postnatal rats

Huang, Y. & Dreyfus, C. F., Sep 4 2013, Neural Development: Methods and Protocols. p. 71-80 10 p. (Methods in Molecular Biology; vol. 1018).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Culturing oligodendrocyte lineage cells from neonatal rats

Fulmer, C. G. & Dreyfus, C. F., Sep 4 2013, Neural Development: Methods and Protocols. p. 81-91 11 p. (Methods in Molecular Biology; vol. 1018).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2012

Introduction to the special issue in honor of Ira B. Black

Chao, M. V. & Dreyfus, C. F., Jun 1 2012, In : Developmental Neurobiology. 72, 6, p. 753-754 2 p.

Research output: Contribution to journalEditorial

2011

Levels of BDNF impact oligodendrocyte lineage cells following a cuprizone lesion

Vondran, M. W., Singh, H., Honeywell, J. Z. & Dreyfus, C. F., Oct 5 2011, In : Journal of Neuroscience. 31, 40, p. 14182-14190 9 p.

Research output: Contribution to journalArticle

74 Scopus citations
2010

BDNF +/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain

Vondran, M. W., Clinton-Luke, P., Honeywell, J. Z. & Dreyfus, C. F., May 1 2010, In : Glia. 58, 7, p. 848-856 9 p.

Research output: Contribution to journalArticle

71 Scopus citations
2009

Brain-derived neurotrophic factor effects on oligodendrocyte progenitors of the basal forebrain are mediated through TrkB and the MAP kinase pathway

Van't Veer, A., Du, Y., Fischer, T. Z., Boetig, D. R., Wood, M. R. & Dreyfus, C. F., Mar 31 2009, In : Journal of Neuroscience Research. 87, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Regulated release of BDNF by cortical oligodendrocytes is mediated through metabotropic glutamate receptors and the PLC pathway

Bagayogo, I. P. & Dreyfus, C. F., Dec 1 2009, In : ASN neuro. 1, 1, p. 1-12 12 p., e00001.

Research output: Contribution to journalArticle

33 Scopus citations

Release of trophic factors and immune molecules from astrocytes

Jean, Y. Y., Bagayogo, I. P. & Dreyfus, C. F., Jan 1 2009, Astrocytes in (Patho)Physiology of the Nervous System. Springer US, p. 351-381 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2008
29 Scopus citations

Effects of behaviorally active ACTH (4-10) analogue - Semax on rat basal forebrain cholinergic neurons

Grivennikov, I. A., Dolotov, O. V., Zolotarev, Y. A., Andreeva, L. A., Myasoedov, N. F., Leacher, L., Black, I. B. & Dreyfus, C. F., May 12 2008, In : Restorative neurology and neuroscience. 26, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Glutamate elicits release of BDNF from basal forebrain astrocytes in a process dependent on metabotropic receptors and the PLC pathway

Jean, Y. Y., Lercher, L. D. & Dreyfus, C. F., Feb 1 2008, In : Neuron Glia Biology. 4, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

59 Scopus citations
2006

Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes

Du, Y., Fischer, T. Z., Clinton-Luke, P., Lercher, L. D. & Dreyfus, C. F., Feb 1 2006, In : Molecular and Cellular Neuroscience. 31, 2, p. 366-375 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
56 Scopus citations
2004

Differential Regulation of Neurotrophin Expression in Basal Forebrain Astrocytes by Neuronal Signals

Wu, H., Friedman, W. & Dreyfus, C., Apr 1 2004, In : Journal of Neuroscience Research. 76, 1, p. 76-85 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
2003

Regionally specific effects of BDNF on oligodendrocytes

Du, Y., Fischer, T. Z., Lee, L. N., Lercher, L. D. & Dreyfus, C. F., Sep 22 2003, In : Developmental Neuroscience. 25, 2-4, p. 116-126 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

The trophic role of oligodendrocytes in the basal forebrain

Dai, X., Lercher, L. D., Clinton, P. M., Du, Y., Livingston, D. L., Vieira, C., Yang, L., Shen, M. M. & Dreyfus, C. F., Jul 1 2003, In : Journal of Neuroscience. 23, 13, p. 5846-5853 8 p.

Research output: Contribution to journalArticle

Open Access
97 Scopus citations
2002

Brain-derived neurotrophic factor: A novel human ovarian follicular protein

Seifer, D. B., Feng, B., Shelden, R. M., Chen, S. & Dreyfus, C. F., Jan 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 2, p. 655-659 5 p.

Research output: Contribution to journalArticle

79 Scopus citations

Neurotrophin-4/5 and neurotrophin-3 are present within the human ovarian follicle but appear to have different paracrine/autocrine functions

Seifer, D. B., Feng, B., Shelden, R. M., Chen, S. & Dreyfus, C., Oct 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 10, p. 4569-4571 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Oligodendrocytes as providers of growth factors

Du, Y. & Dreyfus, C., Jun 15 2002, In : Journal of Neuroscience Research. 68, 6, p. 647-654 8 p.

Research output: Contribution to journalShort survey

178 Scopus citations
2001

Differential regulation of p75 and trkB mRNA expression after depolarizing stimuli or BDNF treatment in basal forebrain neuron cultures

Elliott, R. C., Black, I. B. & Dreyfus, C., Oct 1 2001, In : Journal of Neuroscience Research. 66, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Neuronal signals regulate neurotrophin expression in oligodendrocytes of the basal forebrain

Dai, X., Qu, P. & Dreyfus, C. F., Jun 7 2001, In : Glia. 34, 3, p. 234-239 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
2000

Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury

Dougherty, K. D., Dreyfus, C. F. & Black, I. B., Jan 1 2000, In : Neurobiology of Disease. 7, 6, p. 574-585 12 p.

Research output: Contribution to journalArticle

277 Scopus citations

Multiple ephrins regulate hippocampal neurite outgrowth

Brownlee, H., Gao, P. P., Frisen, J., Dreyfus, C., Zhou, R. & Black, I. B., Sep 18 2000, In : Journal of Comparative Neurology. 425, 2, p. 315-322 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
1999

Ephrin-dependent growth and pruning of hippocampal axons

Gao, P. P., Yue, Y., Cerretti, D. P., Dreyfus, C. & Zhou, R., Mar 30 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 4073-4077 5 p.

Research output: Contribution to journalArticle

87 Scopus citations

Expression of neurotrophins in the adult spinal cord in vivo

Dreyfus, C. F., Dai, X., Lercher, L. D., Racey, B. R., Friedman, W. J. & Black, I. B., Apr 1 1999, In : Journal of Neuroscience Research. 56, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

69 Scopus citations
1998
20 Scopus citations

Neurotransmitters and neurotrophins collaborate to influence brain development

Dreyfus, C. F., Dec 1 1998, In : Perspectives on developmental neurobiology. 5, 4, p. 389-399 11 p.

Research output: Contribution to journalReview article

48 Scopus citations

Transmitter plasticity in the developing brain

Aronson, S. L. & Dreyfus, C., Jan 1 1998, In : Mental Retardation and Developmental Disabilities Research Reviews. 4, 3, p. 150-156 7 p.

Research output: Contribution to journalReview article

Unilateral hippocampal lesions in newborn and adult rats: Effects on spatial memory and BDNF gene expression

Van Praag, H., Qu, P. M., Elliott, R. C., Wu, H., Dreyfus, C. F. & Black, I. B., Apr 1 1998, In : Behavioural Brain Research. 92, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

39 Scopus citations
1996

Regulation of topographic projection in the brain: Elf-1 in the hippocamposeptal system

Gao, P. P., Zhang, J. H., Yokoyama, M., Racey, B., Dreyfus, C. F., Black, I. B. & Zhou, R., Oct 1 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 11161-11166 6 p.

Research output: Contribution to journalArticle

128 Scopus citations

Selective role for trkB neurotrophin receptors in rapid modulation of hippocampal synaptic transmission

Levine, E. S., Dreyfus, C., Black, I. B. & Plummer, M., Jun 1996, In : Molecular Brain Research. 38, 2, p. 300-303 4 p.

Research output: Contribution to journalArticle

57 Scopus citations

The identification of a novel cDNA preferentially expressed in the olfactory-limbic system of the adult rat

Schaar, D., Varia, M. R., Elkabes, S., Ramakrishnan, L., Dreyfus, C. & Black, I. B., May 20 1996, In : Brain research. 721, 1-2, p. 217-228 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Unilateral neonatal hippocampal lesion alters septal innervation and trophism of the entorhinal cortex

Van Praag, H., Alberch, J., Perez-Navarro, E., Wu, H., Qu, P. M., Black, I. B. & Dreyfus, C., Jan 1 1996, In : Experimental Neurology. 141, 1, p. 130-140 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
1995
500 Scopus citations

Developmental regulation of neurotrophin-3 and trk c splice variants in optic nerve gliain vivo

Elkabes, S., Schaar, D., Dreyfus, C. & Black, I. B., Jun 1995, In : Neuroscience. 66, 4, p. 879-889 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Differential effects of NGF and BDNF on voltage-gated calcium currents in embryonic basal forebrain neurons

Levine, E. S., Dreyfus, C., Black, I. B. & Plummer, M., Apr 1995, In : Journal of Neuroscience. 15, 4, p. 3084-3091 8 p.

Research output: Contribution to journalArticle

Open Access
94 Scopus citations

Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells

Mount, H. T. J., Dean, D. O., Alberch, J., Dreyfus, C. & Black, I. B., Sep 26 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 20, p. 9092-9096 5 p.

Research output: Contribution to journalArticle

143 Scopus citations
1994

An improved method detects differential NGF and BDNF gene expression in response to depolarization in cultured hippocampal neurons

Elliott, R. C., Inturrisi, C. E., Black, I. B. & Dreyfus, C. F., Oct 1994, In : Molecular Brain Research. 26, 1-2, p. 81-88 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Dissociation of motor hyperactivity and spatial memory deficits by selective hippocampal lesions in the neonatal rat

Van Praag, H., Dreyfus, C. F. & Black, I. B., Jan 1 1994, In : Journal of Cognitive Neuroscience. 6, 4, p. 321-331 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Embryonic sensory development: Local expression of neurotrophin‐3 and target expression of nerve growth factor

Elkabes, S., Dreyfus, C., Schaar, D. & Black, I. B., Mar 8 1994, In : Journal of Comparative Neurology. 341, 2, p. 204-213 10 p.

Research output: Contribution to journalArticle

55 Scopus citations