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Research Output

2019

Aberrant arc between the common hepatic artery and a replaced right hepatic artery resulting in misperfusion in a patient with a hepatic arterial infusion pump

Hasan, O., Greco, S., Kennedy, T., Carpizo, D., Kempf, J. & Nosher, J., Mar 1 2019, In : Surgical and Radiologic Anatomy. 41, 3, p. 355-358 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combinatorial therapy of zinc metallochaperones with mutant p53 reactivation and diminished copper binding

Zaman, S., Yu, X., Bencivenga, A. F., Blanden, A. R., Liu, Y., Withers, T., Na, B., Blayney, A. J., Gilleran, J., Boothman, D. A., Loh, S. N., Kimball, S. D. & Carpizo, D. R., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 8, p. 1355-1365 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Conditional survival analysis of metastatic colorectal cancer patients living ≥24 months: A single institutional study

Ali, N. D., Donohue, K., Zandieh, S., Chen, C., Moore, D., Poplin, E., Shah, M. M., Nosher, J., Gui, B., Jabbour, S. K., Spencer, K. & Carpizo, D. R., Jun 1 2019, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 42, 6, p. 512-518 7 p.

Research output: Contribution to journalArticle

Flipping the "switch" on mutant p53 by zinc metallochaperones: How a brief pulse of zinc can reactivate mutant p53 to kill cancer

Yu, X. & Carpizo, D. R., Jan 1 2019, In : Oncotarget. 10, 9, p. 918-919 2 p.

Research output: Contribution to journalEditorial

Liver haematoma as a presentation of peliosis hepatis

Dave, Y. A., Gupta, A., Shah, M. M. & Carpizo, D., Feb 1 2019, In : BMJ case reports. 12, 2, e226737.

Research output: Contribution to journalArticle

1 Scopus citations

Outcomes Following Major Oncologic Operations for Non-AIDS-Defining Cancers in the HIV Population: A Matched Comparison to the General Population

Chi, A., Adams, B. E., Sesti, J., Paul, S., Turner, A. L., August, D., Carpizo, D., Kennedy, T., Grandhi, M., Alexander, H. R., Libutti, S. K., Geffner, S. & Langan, R. C., Dec 1 2019, In : World Journal of Surgery. 43, 12, p. 3019-3026 8 p.

Research output: Contribution to journalArticle

Rethinking the role of radiation therapy in the treatment of unresectable hepatocellular carcinoma: A data driven treatment algorithm for optimizing outcomes

Sayan, M., Yegya-Raman, N., Greco, S. H., Gui, B., Zhang, A., Chundury, A., Grandhi, M. S., Hochster, H. S., Kennedy, T. J., Langan, R. C., Malhotra, U., Rustgi, V. K., Shah, M. M., Spencer, K. R., Carpizo, D. R., Nosher, J. L. & Jabbour, S. K., Jan 1 2019, In : Frontiers in Oncology. 9, JUN

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2018

Accessory bile duct: A rare but important anatomical variant

Casabianca, A. S., Shah, M. M. & Carpizo, D., Jan 1 2018, In : BMJ case reports. 2018, 1409.

Research output: Contribution to journalArticle

A novel combined interventional radiologic and hepatobiliary surgical approach to a complex traumatic hilar biliary stricture

NeMoyer, R. E., Shah, M. M., Hasan, O., Nosher, J. L. & Carpizo, D. R., Jan 1 2018, In : International Journal of Surgery Case Reports. 44, p. 185-190 6 p.

Research output: Contribution to journalArticle

Assessment of the Albumin-Bilirubin (ALBI) Grade as a Prognostic Indicator for Hepatocellular Carcinoma Patients Treated with Radioembolization

Gui, B., Weiner, A. A., Nosher, J., Lu, S. E., Foltz, G. M., Hasan, O., Kim, S. K., Gendel, V., Mani, N. B., Carpizo, D. R., Saad, N. E., Kennedy, T. J., Zuckerman, D. A., Olsen, J. R., Parikh, P. J. & Jabbour, S. K., Sep 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 9, p. 861-866 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells

Shimada, K., Reznik, E., Stokes, M. E., Krishnamoorthy, L., Bos, P. H., Song, Y., Quartararo, C. E., Pagano, N. C., Carpizo, D. R., deCarvalho, A. C., Lo, D. C. & Stockwell, B. R., May 17 2018, In : Cell Chemical Biology. 25, 5, p. 585-594.e7

Research output: Contribution to journalArticle

8 Scopus citations

Predictors of Survival after Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases

Weiner, A. A., Gui, B., Newman, N. B., Nosher, J. L., Yousseff, F., Lu, S. E., Foltz, G. M., Carpizo, D., Lowenthal, J., Zuckerman, D. A., Benson, B., Olsen, J. R., Jabbour, S. K. & Parikh, P. J., Aug 2018, In : Journal of Vascular and Interventional Radiology. 29, 8, p. 1094-1100 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Zinc metallochaperones as Mutant p53 reactivators: A new paradigm in cancer therapeutics

Kogan, S. & Carpizo, D. R., Jun 2018, In : Cancers. 10, 6, 166.

Research output: Contribution to journalReview article

3 Scopus citations

Zinc metallochaperones reactivate mutant p53 using an on/off switch mechanism: A new paradigm in cancer therapeutics

Yu, X., Kogan, S., Chen, Y., Tsang, A. T., Withers, T., Lin, H., Gilleran, J., Buckley, B., Moore, D., Bertino, J., Chan, C., Kimball, S., Loh, S. N. & Carpizo, D., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4505-4517 13 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

A Comparison of Yttrium-90 Microsphere Radioembolization to Hepatic Arterial Infusional Chemotherapy for Patients with Chemo-refractory Hepatic Colorectal Metastases

Cercek, A., Gendel, V., Jabbour, S., Moore, D., Chen, C., Nosher, J., Capanu, M., Chou, J. F., Boucher, T., Kemeny, N. & Carpizo, D., Jul 1 2017, In : Current treatment options in oncology. 18, 7, 42.

Research output: Contribution to journalReview article

1 Scopus citations

Thiosemicarbazones functioning as zinc metallochaperones to reactivate mutant p53

Yu, X., Blanden, A., Tsang, A. T., Zaman, S., Liu, Y., Gilleran, J., Bencivenga, A. F., Kimball, S. D., Loh, S. N. & Carpizo, D. R., Jun 2017, In : Molecular Pharmacology. 91, 6, p. 567-575 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

U1 adaptors suppress the KRAS-MYC oncogenic axis in human pancreatic cancer xenografts

Tsang, A. T., Dudgeon, C., Yi, L., Yu, X., Goraczniak, R., Donohue, K., Kogan, S., Brenneman, M. A., Ho, E. S., Gunderson, S. I. & Carpizo, D. R., Aug 2017, In : Molecular Cancer Therapeutics. 16, 8, p. 1445-1455 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

Pharmacological targeting of mutant p53

Kogan, S. & Carpizo, D., Jan 1 2016, In : Translational Cancer Research. 5, 6, p. 698-706 9 p.

Research output: Contribution to journalReview article

3 Scopus citations
2015

A sensitive liquid chromatography-mass spectrometry bioanalytical assay for a novel anticancer candidate - ZMC1

Lin, H., Yu, X., Eng, O. S., Buckley, B., Kong, A-N., Bertino, J., Carpizo, D. & Gounder, M. K., Nov 2015, In : Biomedical Chromatography. 29, 11, p. 1708-1714 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Erratum: Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore (Molecular Pharmacology (2015) 87 (825-831))

Blanden, R., Yu, X., Aaron, J. W., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N., Dec 1 2015, In : Molecular Pharmacology. 88, 6, 1 p.

Research output: Contribution to journalComment/debate

Fluid administration and morbidity in transhiatal esophagectomy

Eng, O. S., Arlow, R. L., Moore, D., Chen, C., Langenfeld, J., August, D. & Carpizo, D., Jun 12 2015, In : Journal of Surgical Research. 200, 1, p. 91-97 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Hepatocellular Carcinoma Without Cirrhosis Presenting With Hypercalcemia: Case Report and Literature Review

Newman, N. B., Jabbour, S., Hon, J. D. C., Berman, J. J., Malik, D., Carpizo, D. & Moss, R. A., Jan 1 2015, In : Journal of Clinical and Experimental Hepatology. 5, 2, p. 163-166 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing antiapoptotic proteins Mcl-1 and Bcl-2

Yue, W., Zheng, X., Lin, Y., Yang, C. S., Xu, Q., Carpizo, D., Huang, H., DiPaola, R. S. & Tan, X. L., Jan 1 2015, In : Oncotarget. 6, 25, p. 21208-21224 17 p.

Research output: Contribution to journalArticle

48 Scopus citations

Outcomes of microwave ablation for colorectal cancer liver metastases: A single center experience

Eng, O. S., Tsang, A. T., Moore, D., Chen, C., Narayanan, S., Gannon, C. J., August, D. A., Carpizo, D. R. & Melstrom, L. G., Mar 1 2015, In : Journal of Surgical Oncology. 111, 4, p. 410-413 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing

Chiou, S. H., Winters, I. P., Wang, J., Naranjo, S., Dudgeon, C., Tamburini, F. B., Brady, J. J., Yang, D., Grüner, B. M., Chuang, C. H., Caswell, D. R., Zeng, H., Chu, P., Kim, G. E., Carpizo, D. R., Kim, S. K. & Winslow, M. M., Jul 15 2015, In : Genes and Development. 29, 14, p. 1576-1585 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

Reactivating mutant p53 using small molecules as zinc metallochaperones: Awakening a sleeping giant in cancer

Blanden, A. R., Yu, X., Loh, S. N., Levine, A. J. & Carpizo, D., Nov 1 2015, In : Drug Discovery Today. 20, 11, p. 1391-1397 7 p.

Research output: Contribution to journalReview article

36 Scopus citations

Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore

Blanden, A. R., Yu, X., Wolfe, A. J., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N., May 1 2015, In : Molecular Pharmacology. 87, 5, p. 825-831 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

The relationship of perioperative fluid administration to outcomes in colorectal and pancreatic surgery: A review of the literature

Eng, O. S., Melstrom, L. G. & Carpizo, D. R., Mar 1 2015, In : Journal of Surgical Oncology. 111, 4, p. 472-477 6 p.

Research output: Contribution to journalReview article

9 Scopus citations
2014

Pilot study of angiogenic response to yttrium-90 radioembolization with resin microspheres

Carpizo, D. R., Gensure, R. H., Yu, X., Gendel, V. M., Greene, S. J., Moore, D. F., Jabbour, S. K. & Nosher, J. L., Feb 2014, In : Journal of Vascular and Interventional Radiology. 25, 2, p. 297-306.e1

Research output: Contribution to journalArticle

16 Scopus citations

Small molecule compounds targeting the p53 pathway: Are we finally making progress?

Yu, X., Narayanan, S., Vazquez, A. & Carpizo, D. R., Jul 2014, In : Apoptosis. 19, 7, p. 1055-1068 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism

Yu, X., Blanden, A. R., Narayanan, S., Jayakumar, L., Lubin, D., Augeri, D., David Kimball, S., Loh, S. N. & Carpizo, D. R., Jan 1 2014, In : Oncotarget. 5, 19, p. 8879-8892 14 p.

Research output: Contribution to journalArticle

46 Scopus citations
2013

Intraoperative fluid administration is associated with perioperative outcomes in pancreaticoduodenectomy: A single center retrospective analysis

Eng, O. S., Goswami, J., Moore, D., Chen, C., Gannon, C. J., August, D. A. & Carpizo, D. R., Sep 1 2013, In : Journal of Surgical Oncology. 108, 4, p. 242-247 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Safety and efficacy of LigaSure usage in pancreaticoduodenectomy

Eng, O. S., Goswami, J., Moore, D., Chen, C., Brumbaugh, J., Gannon, C. J., August, D. A. & Carpizo, D. R., Oct 2013, In : HPB. 15, 10, p. 747-752 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2012

Allele-Specific p53 Mutant Reactivation

Yu, X., Vazquez, A., Levine, A. J. & Carpizo, D. R., May 25 2012, In : Cancer Cell. 21, 5, p. 614-625 12 p.

Research output: Contribution to journalArticle

171 Scopus citations

Evaluation of Hepatic Tumor Response to Yttrium-90 Radioembolization Therapy Using Texture Signatures Generated from Contrast-enhanced CT Images

Gensure, R. H., Foran, D. J., Lee, V. M., Gendel, V. M., Jabbour, S. K., Carpizo, D. R., Nosher, J. L. & Yang, L., Oct 1 2012, In : Academic radiology. 19, 10, p. 1201-1207 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2009

Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion

Rodríguez-Manzaneque, J. C., Carpizo, D., Plaza-Calonge, M. D. C., Torres-Collado, A. X., Thai, S. N. M., Simons, M., Horowitz, A. & Iruela-Arispe, M. L., Apr 1 2009, In : International Journal of Biochemistry and Cell Biology. 41, 4, p. 800-810 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Liver resection for metastatic colorectal cancer in patients with concurrent extrahepatic disease: Results in 127 patients treated at a single center

Carpizo, D., Are, C., Jarnagin, W., Dematteo, R., Fong, Y., Gönen, M., Blumgart, L. & D'Angelica, M., Aug 1 2009, In : Annals of Surgical Oncology. 16, 8, p. 2138-2146 9 p.

Research output: Contribution to journalArticle

110 Scopus citations

Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease

Carpizo, D. & D'Angelica, M., Sep 1 2009, In : Annals of Surgical Oncology. 16, 9, p. 2411-2421 11 p.

Research output: Contribution to journalReview article

34 Scopus citations

Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease

Carpizo, D. & D'Angelica, M., Aug 1 2009, In : The Lancet Oncology. 10, 8, p. 801-809 9 p.

Research output: Contribution to journalReview article

69 Scopus citations

Management and Extent of Resection for Intrahepatic Cholangiocarcinoma

Carpizo, D. R. & D'Angelica, M., Apr 1 2009, In : Surgical Oncology Clinics of North America. 18, 2, p. 289-305 17 p.

Research output: Contribution to journalReview article

21 Scopus citations

Metastatic Liver Cancer: Treatment: Surgical therapy for hepatic colorectal metastases

Carpizo, D. & Fong, Y., Jan 14 2009, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach. Blackwell Publishing Ltd, p. 469-480 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2008

Current management of cystic neoplasms of the pancreas

Carpizo, D. R., Allen, P. J. & Brennan, M. F., Oct 2008, In : Surgeon. 6, 5, p. 298-307 10 p.

Research output: Contribution to journalReview article

22 Scopus citations

Reoperative Breast Surgery

Carpizo, D. R., Brooks, M. & Chang, H., May 9 2008, Handbook of Reoperative General Surgery. Blackwell Publishing Ltd, p. 193-212 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2005

Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

Lee, S., Jilan, S. M., Nikolova, G. V., Carpizo, D. & Luisa Iruela-Arispe, M., May 1 2005, In : Journal of Cell Biology. 169, 4, p. 681-691 11 p.

Research output: Contribution to journalArticle

532 Scopus citations
2003

ADAMTS1: A matrix metalloprotease with angioinhibitory properties

Iruela-Arispe, M. L., Carpizo, D. & Luque, A., Jan 1 2003, In : Annals of the New York Academy of Sciences. 995, p. 183-190 8 p.

Research output: Contribution to journalArticle

75 Scopus citations

ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165

Luque, A., Carpizo, D. R. & Iruela-Arispe, M. L., Jul 27 2003, In : Journal of Biological Chemistry. 278, 26, p. 23656-23665 10 p.

Research output: Contribution to journalArticle

186 Scopus citations
2000

Endogenous regulators of angiogenesis - Emphasis on proteins with thrombospondin - Type I motifs

Carpizo, D. & Iruela-Arispe, M. L., Dec 1 2000, In : Cancer and Metastasis Reviews. 19, 1-2, p. 159-165 7 p.

Research output: Contribution to journalReview article

37 Scopus citations
1998

Acute acid exposure increases rabbit esophageal cell proliferation

Carpizo, D. R., Reaka, A. J. H., Reid Glaws, W., Pooley, N., Schmidt, L., Halline, A. G., Goldstein, J. L. & Layden, T. J., Jan 1 1998, In : Journal of Laboratory and Clinical Medicine. 131, 2, p. 157-162 6 p.

Research output: Contribution to journalArticle

8 Scopus citations