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Research Output 1998 2019

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2019

Aberrant arc between the common hepatic artery and a replaced right hepatic artery resulting in misperfusion in a patient with a hepatic arterial infusion pump

Hasan, O., Greco, S., Kennedy, T., Carpizo, D., Kempf, J. & Nosher, J., Mar 1 2019, In : Surgical and Radiologic Anatomy. 41, 3, p. 355-358 4 p.

Research output: Contribution to journalArticle

Infusion Pumps
Hepatic Artery
Liver
Nuclear Medicine
Perfusion

Conditional Survival Analysis of Metastatic Colorectal Cancer Patients Living ≥24 Months: A Single Institutional Study

Ali, N. D., Donohue, K., Zandieh, S., Chen, C., Moore, D., Poplin, E., Shah, M. M., Nosher, J., Gui, B., Jabbour, S., Spencer, K. & Carpizo, D., Jan 1 2019, In : American Journal of Clinical Oncology: Cancer Clinical Trials.

Research output: Contribution to journalArticle

Survival Analysis
Colorectal Neoplasms

Liver haematoma as a presentation of peliosis hepatis

Dave, Y. A., Gupta, A., Shah, M. M. & Carpizo, D., Feb 1 2019, In : BMJ case reports. 12, 2, e226737.

Research output: Contribution to journalArticle

Peliosis Hepatis
Hematoma
Liver
Blood Vessels
Hemorrhage
2018

Accessory bile duct: A rare but important anatomical variant

Casabianca, A. S., Shah, M. M. & Carpizo, D., Jan 1 2018, In : BMJ case reports. 2018, 1409.

Research output: Contribution to journalArticle

Bile Ducts
Sepsis
Pancreaticoduodenectomy
Cholestasis
Common Bile Duct

A novel combined interventional radiologic and hepatobiliary surgical approach to a complex traumatic hilar biliary stricture

NeMoyer, R. E., Shah, M. M., Hasan, O., Nosher, J. L. & Carpizo, D., Jan 1 2018, In : International Journal of Surgery Case Reports. 44, p. 185-190 6 p.

Research output: Contribution to journalArticle

Pathologic Constriction
Common Hepatic Duct
Wounds and Injuries
Interventional Radiology
Gunshot Wounds
6 Citations (Scopus)

Assessment of the Albumin-Bilirubin (ALBI) Grade as a Prognostic Indicator for Hepatocellular Carcinoma Patients Treated with Radioembolization

Gui, B., Weiner, A. A., Nosher, J., Lu, S-E., Foltz, G. M., Hasan, O., Kim, S. K., Gendel, V., Mani, N. B., Carpizo, D., Saad, N. E., Kennedy, T., Zuckerman, D. A., Olsen, J. R., Parikh, P. J. & Jabbour, S., Sep 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 9, p. 861-866 6 p.

Research output: Contribution to journalArticle

Bilirubin
Albumins
Hepatocellular Carcinoma
Survival
Liver Neoplasms
2 Citations (Scopus)

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells

Shimada, K., Reznik, E., Stokes, M. E., Krishnamoorthy, L., Bos, P. H., Song, Y., Quartararo, C. E., Pagano, N. C., Carpizo, D., deCarvalho, A. C., Lo, D. C. & Stockwell, B. R., May 17 2018, In : Cell Chemical Biology. 25, 5, p. 585-594.e7

Research output: Contribution to journalArticle

Oxidative stress
Glioblastoma
Cell Cycle Checkpoints
Copper
Oxidative Stress
3 Citations (Scopus)

Predictors of Survival after Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases

Weiner, A. A., Gui, B., Newman, N. B., Nosher, J. L., Yousseff, F., Lu, S-E., Foltz, G. M., Carpizo, D., Lowenthal, J., Zuckerman, D. A., Benson, B., Olsen, J. R., Jabbour, S. & Parikh, P. J., Aug 1 2018, In : Journal of Vascular and Interventional Radiology. 29, 8, p. 1094-1100 7 p.

Research output: Contribution to journalArticle

Yttrium
Liver Neoplasms
Colorectal Neoplasms
Neoplasm Metastasis
Survival
4 Citations (Scopus)

Zinc metallochaperones reactivate mutant p53 using an on/off switch mechanism: A new paradigm in cancer therapeutics

Yu, X., Kogan, S., Chen, Y., Tsang, A. T., Withers, T., Lin, H., Gilleran, J., Buckley, B., Moore, D., Bertino, J., Chan, C., Kimball, S., Loh, S. N. & Carpizo, D., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4505-4517 13 p.

Research output: Contribution to journalArticle

Metallochaperones
Zinc
Neoplasms
Therapeutics
Pharmacokinetics
2017
8 Citations (Scopus)

Thiosemicarbazones functioning as zinc metallochaperones to reactivate mutant p53

Yu, X., Blanden, A., Tsang, A. T., Zaman, S., Liu, Y., Gilleran, J., Bencivenga, A. F., Kimball, S., Loh, S. N. & Carpizo, D., Jun 1 2017, In : Molecular Pharmacology. 91, 6, p. 567-575 9 p.

Research output: Contribution to journalArticle

Metallochaperones
Thiosemicarbazones
Zinc
Chelating Agents
Reactive Oxygen Species
3 Citations (Scopus)

U1 adaptors suppress the KRAS-MYC oncogenic axis in human pancreatic cancer xenografts

Tsang, A. T., Dudgeon, C., Yi, L., Yu, X., Goraczniak, R., Donohue, K., Kogan, S., Brenneman, M. A., Ho, E. S., Gunderson, S. & Carpizo, D., Aug 1 2017, In : Molecular Cancer Therapeutics. 16, 8, p. 1445-1455 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Heterografts
Nanoparticles
Neoplasms
Staining and Labeling
2015
3 Citations (Scopus)

A sensitive liquid chromatography-mass spectrometry bioanalytical assay for a novel anticancer candidate - ZMC1

Lin, H., Yu, X., Eng, O. S., Buckley, B., Kong, A-N., Bertino, J., Carpizo, D. & Gounder, M. K., Nov 1 2015, In : Biomedical Chromatography. 29, 11, p. 1708-1714 7 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography
Mass spectrometry
Assays
Mass Spectrometry
3 Citations (Scopus)

Fluid administration and morbidity in transhiatal esophagectomy

Eng, O. S., Arlow, R. L., Moore, D., Chen, C., Langenfeld, J., August, D. & Carpizo, D., Jun 12 2015, In : Journal of Surgical Research. 200, 1, p. 91-97 7 p.

Research output: Contribution to journalArticle

Esophagectomy
Morbidity
Albumins
Serum Albumin
Malnutrition
1 Citation (Scopus)

Hepatocellular Carcinoma Without Cirrhosis Presenting With Hypercalcemia: Case Report and Literature Review

Newman, N. B., Jabbour, S., Hon, J. D. C., Berman, J. J., Malik, D., Carpizo, D. & Moss, R. A., Jan 1 2015, In : Journal of Clinical and Experimental Hepatology. 5, 2, p. 163-166 4 p.

Research output: Contribution to journalArticle

Hypercalcemia
Hepatocellular Carcinoma
Fibrosis
zoledronic acid
Liver
41 Citations (Scopus)

Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing antiapoptotic proteins Mcl-1 and Bcl-2

Yue, W., Zheng, X., Lin, Y., Yang, C., Xu, Q., Carpizo, D., Huang, H., DiPaola, R. S. & Tan, X., Jan 1 2015, In : Oncotarget. 6, 25, p. 21208-21224 17 p.

Research output: Contribution to journalArticle

Metformin
Pancreatic Neoplasms
Aspirin
Growth
Proteins
15 Citations (Scopus)

Outcomes of microwave ablation for colorectal cancer liver metastases: A single center experience

Eng, O. S., Tsang, A. T., Moore, D., Chen, C., Narayanan, S., Gannon, C. J., August, D., Carpizo, D. & Melstrom, L. G., Mar 1 2015, In : Journal of Surgical Oncology. 111, 4, p. 410-413 4 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Microwaves
Colorectal Neoplasms
Neoplasm Metastasis
Recurrence
74 Citations (Scopus)

Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing

Chiou, S. H., Winters, I. P., Wang, J., Naranjo, S., Dudgeon, C., Tamburini, F. B., Brady, J. J., Yang, D., Grüner, B. M., Chuang, C. H., Caswell, D. R., Zeng, H., Chu, P., Kim, G. E., Carpizo, D., Kim, S. K. & Winslow, M. M., Jul 15 2015, In : Genes and Development. 29, 14, p. 1576-1585 10 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Pancreatic Neoplasms
Adenocarcinoma
Neoplasms
Guide RNA
27 Citations (Scopus)

Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore

Blanden, A. R., Yu, X., Wolfe, A. J., Gilleran, J. A., Augeri, D., O'Dell, R. S., Olson, E. C., Kimball, S., Emge, T., Movileanu, L., Carpizo, D. & Loh, S. N., May 1 2015, In : Molecular Pharmacology. 87, 5, p. 825-831 7 p.

Research output: Contribution to journalArticle

Metallochaperones
Ionophores
Zinc
Neoplasms
Metals
2014
15 Citations (Scopus)

Pilot study of angiogenic response to yttrium-90 radioembolization with resin microspheres

Carpizo, D., Gensure, R. H., Yu, X., Gendel, V. M., Greene, S. J., Moore, D., Jabbour, S. & Nosher, J. L., Jan 1 2014, In : Journal of Vascular and Interventional Radiology. 25, 2

Research output: Contribution to journalArticle

Yttrium
Microspheres
Cytokines
Angiopoietin-2
Follistatin
39 Citations (Scopus)

Small molecule compounds targeting the p53 pathway: Are we finally making progress?

Yu, X., Narayanan, S., Vazquez, A. & Carpizo, D., Jan 1 2014, In : Apoptosis. 19, 7, p. 1055-1068 14 p.

Research output: Contribution to journalArticle

Molecules
Genes
Pharmaceutical Preparations
Neoplasms
Mutation
32 Citations (Scopus)

Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism

Yu, X., Blanden, A. R., Narayanan, S., Jayakumar, L., Lubin, D., Augeri, D., Kimball, S., Loh, S. N. & Carpizo, D., Jan 1 2014, In : Oncotarget. 5, 19, p. 8879-8892 14 p.

Research output: Contribution to journalArticle

Metallochaperones
Zinc
Pharmaceutical Preparations
Pharmaceutical Chemistry
Mutant Proteins
2013
24 Citations (Scopus)

Intraoperative fluid administration is associated with perioperative outcomes in pancreaticoduodenectomy: A single center retrospective analysis

Eng, O. S., Goswami, J., Moore, D., Chen, C., Gannon, C. J., August, D. & Carpizo, D., Sep 1 2013, In : Journal of Surgical Oncology. 108, 4, p. 242-247 6 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Serum Albumin
Albumins
Regression Analysis
Length of Stay
7 Citations (Scopus)

Safety and efficacy of LigaSure usage in pancreaticoduodenectomy

Eng, O. S., Goswami, J., Moore, D., Chen, C., Brumbaugh, J., Gannon, C. J., August, D. & Carpizo, D., Jan 1 2013, In : HPB. 15, 10, p. 747-752 6 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Safety
Operative Time
Blood Vessels
Hot Temperature
2012
147 Citations (Scopus)

Allele-Specific p53 Mutant Reactivation

Yu, X., Vazquez, A., Levine, A. J. & Carpizo, D., May 25 2012, In : Cancer Cell. 21, 5, p. 614-625 12 p.

Research output: Contribution to journalArticle

Alleles
Thiosemicarbazones
National Cancer Institute (U.S.)
Mutant Proteins
Growth
10 Citations (Scopus)

Evaluation of Hepatic Tumor Response to Yttrium-90 Radioembolization Therapy Using Texture Signatures Generated from Contrast-enhanced CT Images

Gensure, R. H., Foran, D., Lee, V. M., Gendel, V. M., Jabbour, S., Carpizo, D., Nosher, J. L. & Yang, L., Oct 1 2012, In : Academic radiology. 19, 10, p. 1201-1207 7 p.

Research output: Contribution to journalArticle

Yttrium
Survival
Liver
Liver Neoplasms
Neoplasms
2009
43 Citations (Scopus)

Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion

Rodríguez-Manzaneque, J. C., Carpizo, D., Plaza-Calonge, M. D. C., Torres-Collado, A. X., Thai, S. N. M., Simons, M., Horowitz, A. & Iruela-Arispe, M. L., Apr 1 2009, In : International Journal of Biochemistry and Cell Biology. 41, 4, p. 800-810 11 p.

Research output: Contribution to journalArticle

Syndecan-4
Adhesion
Defects
Cell Movement
Null Lymphocytes
105 Citations (Scopus)

Liver resection for metastatic colorectal cancer in patients with concurrent extrahepatic disease: Results in 127 patients treated at a single center

Carpizo, D., Are, C., Jarnagin, W., Dematteo, R., Fong, Y., Gönen, M., Blumgart, L. & D'Angelica, M., Aug 1 2009, In : Annals of Surgical Oncology. 16, 8, p. 2138-2146 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Liver
Survival
Neoplasm Metastasis
Recurrence
2005
515 Citations (Scopus)

Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

Lee, S., Jilan, S. M., Nikolova, G. V., Carpizo, D. & Luisa Iruela-Arispe, M., May 1 2005, In : Journal of Cell Biology. 169, 4, p. 681-691 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Vascular Endothelial Growth Factor A
Biological Availability
Blood Vessels
Neoplasms
2003
74 Citations (Scopus)

ADAMTS1: A matrix metalloprotease with angioinhibitory properties

Iruela-Arispe, M. L., Carpizo, D. & Luque, A., Jan 1 2003, In : Annals of the New York Academy of Sciences. 995, p. 183-190 8 p.

Research output: Contribution to journalArticle

Metalloproteases
Thrombospondin 1
Tumors
Vascular Endothelial Growth Factor A
Intercellular Signaling Peptides and Proteins
180 Citations (Scopus)

ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165

Luque, A., Carpizo, D. & Iruela-Arispe, M. L., Jul 27 2003, In : Journal of Biological Chemistry. 278, 26, p. 23656-23665 10 p.

Research output: Contribution to journalArticle

Endothelial cells
Cell proliferation
Vascular Endothelial Growth Factor A
Endothelial Cells
Cell Proliferation
1998
8 Citations (Scopus)

Acute acid exposure increases rabbit esophageal cell proliferation

Carpizo, D., Reaka, A. J. H., Reid Glaws, W., Pooley, N., Schmidt, L., Halline, A. G., Goldstein, J. L. & Layden, T. J., Jan 1 1998, In : Journal of Laboratory and Clinical Medicine. 131, 2, p. 157-162 6 p.

Research output: Contribution to journalArticle

Cell proliferation
Ornithine Decarboxylase
Cell Proliferation
Enzyme activity
Bromodeoxyuridine