• 12576 Citations
  • 66 h-Index
1982 …2020

Research output per year

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Research Output

2014

Reply to "detection of multiple fungal species in blood samples by real-time PCR: An interpretative challenge"

Zhao, Y., Kontoyiannis, D. P., Roilides, E., Walsh, T. J. & Perlin, D. S., Sep 2014, In : Journal of clinical microbiology. 52, 9, 1 p.

Research output: Contribution to journalLetter

Reply to "Not over yet: Fungal infections following methyl prednisolone injections smoulder on"

Zhao, Y., Kontoyiannis, D. P., Roilides, E., Walsh, T. J. & Perlin, D. S., Sep 2014, In : Journal of clinical microbiology. 52, 9, 1 p.

Research output: Contribution to journalLetter

Set of classical PCRs for detection of mutations in Candida glabrata FKS genes linked with echinocandin resistance

Dudiuk, C., Gamarra, S., Leonardeli, F., Jimenez-Ortigosa, C., Vitale, R. G., Afeltra, J., Perlin, D. S. & Garcia-Effron, G., Jul 2014, In : Journal of clinical microbiology. 52, 7, p. 2609-2614 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Target enzyme mutations confer differential echinocandin susceptibilities in Candida kefyr

Staab, J. F., Neofytos, D., Rhee, P., Jimeńez-Ortigosa, C., Zhang, S. X., Perlin, D. S. & Marr, K. A., Sep 2014, In : Antimicrobial agents and chemotherapy. 58, 9, p. 5421-5427 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013
26 Scopus citations

Azole resistance in Aspergillus fumigatus from bronchoalveolar lavage fluid samples of patients with chronic diseases

Zhao, Y., Stensvold, C. R., Perlin, D. S. & Arendrup, M. C., 2013, In : Journal of Antimicrobial Chemotherapy. 68, 7, p. 1497-1504 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Candida krusei colonization in patients with gastrointestinal diseases

Huong, D. T., Zhao, Y., Nguyet, N. T., Loan, T. T., Binh, N. T. T., Thinh, N. V., Hanh, N. T. H., Perez-Perez, G. I. & Perlin, D. S., Nov 2013, In : Medical mycology. 51, 8, p. 884-887 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Characterization of porin expression in Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae identifies isolates most susceptible to the combination of colistin and carbapenems

Hong, J. H., Clancy, C. J., Cheng, S., Shields, R. K., Chen, L., Doi, Y., Zhao, Y., Perlin, D. S., Kreiswirth, B. N. & Nguyen, M. H., May 2013, In : Antimicrobial agents and chemotherapy. 57, 5, p. 2147-2153 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Epidemiology and molecular characterization of bacteremia due to carbapenem-resistant klebsiella pneumoniae in transplant recipients

Clancy, C. J., Chen, L., Shields, R. K., Zhao, Y., Cheng, S., Chavda, K. D., Hao, B., Hong, J. H., Doi, Y., Kwak, E. J., Silveira, F. P., Abdel-Massih, R., Bogdanovich, T., Humar, A., Perlin, D. S., Kreiswirth, B. N. & Hong Nguyen, M., Oct 1 2013, In : American Journal of Transplantation. 13, 10, p. 2619-2633 15 p.

Research output: Contribution to journalArticle

66 Scopus citations
24 Scopus citations

Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts

Pratt, A., Garcia-Effron, G., Zhao, Y., Park, S., Mustaev, A., Pillai, S. & Perlin, D. S., Jan 2013, In : Medical mycology. 51, 1, p. 103-107 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Increasing echinocandin resistance in candida glabrata: Clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations

Alexander, B. D., Johnson, M. D., Pfeiffer, C. D., Jiménez-Ortigosa, C., Catania, J., Booker, R., Castanheira, M., Messer, S. A., Perlin, D. S. & Pfaller, M. A., Jun 15 2013, In : Clinical Infectious Diseases. 56, 12, p. 1724-1732 9 p.

Research output: Contribution to journalArticle

414 Scopus citations

Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility

Datta, K., Rhee, P., Byrnes, E., Garcia-Effron, G., Perlin, D. S., Staab, J. F. & Marr, K. A., Sep 1 2013, In : Journal of clinical microbiology. 51, 9, p. 3090-3093 4 p.

Research output: Contribution to journalArticle

29 Scopus citations

Molecular characterization of AfuFleA, an l-fucose-specific lectin from Aspergillus fumigatus

Kuboi, S., Ishimaru, T., Tamada, S., Bernard, E. M., Perlin, D. S. & Armstrong, D., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 6, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Multilocus sequence typing of Candida albicans isolates from candidemia and superficial candidiasis in Israel

Alastruey-Izquierdo, A., Mandelblat, M., Ben Ami, R., Perlin, D. S. & Segal, E., Oct 2013, In : Medical mycology. 51, 7, p. 755-758 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Mutations of the ompK36 porin gene and promoter impact responses of sequence Type 258, KPC-2-producing Klebsiella pneumoniae strains to doripenem and doripenem-colistin

Clancy, C. J., Chen, L., Hong, J. H., Cheng, S., Hao, B., Shields, R. K., Farrell, A. N., Doi, Y., Zhao, Y., Perlin, D. S., Kreiswirth, B. N. & Nguyen, M. H., Nov 1 2013, In : Antimicrobial agents and chemotherapy. 57, 11, p. 5258-5265 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Pharmacokinetics of posaconazolewithin epithelial cells and fungi: Insights into potential mechanisms of action during treatment and prophylaxis

Campoli, P., Perlin, D. S., Kristof, A. S., White, T. C., Filler, S. G. & Sheppard, D. C., Nov 15 2013, In : Journal of Infectious Diseases. 208, 10, p. 1717-1728 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Quantitative detection of Aspergillus spp. by real-time nucleic acid sequence-based amplification

Zhao, Y. & Perlin, D. S., 2013, Fungal Diagnostics: Methods and Protocols. Humana Press Inc., p. 83-92 10 p. (Methods in Molecular Biology; vol. 968).

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis

Vella, A., De Carolis, E., Vaccaro, L., Posteraro, P., Perlin, D. S., Kostrzewa, M., Posteraro, B. & Sanguinetti, M., Sep 1 2013, In : Journal of clinical microbiology. 51, 9, p. 2964-2969 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

What can we learn and what do we need to know amidst the iatrogenic outbreak of exserohilum rostratum meningitis?

Kontoyiannis, D. P., Perlin, D. S., Roilides, E. & Walsh, T. J., Sep 15 2013, In : Clinical Infectious Diseases. 57, 6, p. 853-859 7 p.

Research output: Contribution to journalReview article

24 Scopus citations
2012

Comparison of dimethyl sulfoxide and water as solvents for echinocandin susceptibility testing by the EUCAST methodology

Alastruey-Izquierdo, A., Gómez-López, A., Arendrup, M. C., Lass-Florl, C., Hope, W. W., Perlin, D. S., Rodriguez-Tudela, J. L. & Cuenca-Estrella, M., Jul 2012, In : Journal of clinical microbiology. 50, 7, p. 2509-2512 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Comparison of dimethyl sulfoxide and water as solvents for echinocandin susceptibility testing by the EUCAST methodology (Journal of Clinical Microbiology (2012) 50, 7 (2509-2512))

Alastruey-Izquierdo, A., Gómez-López, A., Arendrup, M. C., Lass-Florl, C., Hope, W. W., Perlin, D. S., Rodriguez-Tudela, J. L. & Cuenca-Estrella, M., Sep 2012, In : Journal of clinical microbiology. 50, 9, 1 p.

Research output: Contribution to journalComment/debate

Development stage-specific proteomic profiling uncovers small, lineage specific proteins most abundant in the Aspergillus Fumigatus conidial proteome

Suh, M. J., Fedorova, N. D., Cagas, S. E., Hastings, S., Fleischmann, R. D., Peterson, S. N., Perlin, D. S., Nierman, W. C., Pieper, R. & Momany, M., Apr 30 2012, In : Proteome Science. 10, 1, 30.

Research output: Contribution to journalArticle

42 Scopus citations

Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations

Arendrup, M. C., Perlin, D. S., Jensen, R. H., Howard, S. J., Goodwin, J. & Hope, W., May 1 2012, In : Antimicrobial agents and chemotherapy. 56, 5, p. 2435-2442 8 p.

Research output: Contribution to journalArticle

77 Scopus citations

Epidemiology and echinocandin susceptibility of Candida parapsilosis sensu lato species isolated from bloodstream infections at a Spanish University Hospital

Garcia-Effron, G., Canton, E., Pemán, J., Dilger, A., Romá, E. & Perlin, D. S., Nov 1 2012, In : Journal of Antimicrobial Chemotherapy. 67, 11, p. 2739-2748 10 p., dks271.

Research output: Contribution to journalArticle

33 Scopus citations

Expression turnover profiling to monitor the antifungal activities of amphotericin B, voriconazole, and micafungin against Aspergillus fumigatus

Zhao, Y., Paderu, P., Park, S., Dukhan, A., Senter, M. & Perlin, D. S., May 1 2012, In : Antimicrobial agents and chemotherapy. 56, 5, p. 2770-2772 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Fks1 and Fks2 are functionally redundant but differentially regulated in Candida glabrata: implications for echinocandin resistance

Katiyar, S. K., Alastruey-Izquierdo, A., Healey, K. R., Johnson, M. E., Perlin, D. S. & Edlind, T. D., Dec 1 2012, In : Antimicrobial agents and chemotherapy. 56, 12, p. 6304-6309 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor

Do, Y., Didierlaurent, A. M., Ryu, S., Koh, H., Park, C. G., Park, S., Perlin, D. S., Powell, B. S. & Steinman, R. M., Oct 5 2012, In : Vaccine. 30, 45, p. 6359-6367 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Molecular mechanisms of cryptococcal meningitis

Liu, T. B., Perlin, D. S. & Xue, C., Jan 1 2012, In : Virulence. 3, 2, p. 173-181 9 p.

Research output: Contribution to journalReview article

61 Scopus citations

Preface for Advances Against Aspergillosis

Clemons, K. V., Perlin, D. S. & Richardson, M., Dec 2012, In : Annals of the New York Academy of Sciences. 1272, 1, p. vii-viii

Research output: Contribution to journalEditorial

Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species

De Carolis, E., Vella, A., Florio, A. R., Posteraro, P., Perlin, D. S., Sanguinetti, M. & Posteraro, B., Jul 1 2012, In : Journal of clinical microbiology. 50, 7, p. 2479-2483 5 p.

Research output: Contribution to journalArticle

76 Scopus citations
2011

Are we ready for novel detection methods to treat respiratory pathogens in hospital-acquired pneumonia?

Endimiani, A., Hujer, K. M., Hujer, A. M., Kurz, S., Jacobs, M. R., Perlin, D. S. & Bonomo, R. A., May 1 2011, In : Clinical Infectious Diseases. 52, SUPPL. 4, p. S373-S383

Research output: Contribution to journalArticle

62 Scopus citations

Assessment of two new molecular methods for identification of Candida parapsilosis sensu lato species

Garcia-Effron, G., Canton, E., Pemán, J., Dilger, A., Romá, E. & Perlin, D. S., Sep 1 2011, In : Journal of clinical microbiology. 49, 9, p. 3257-3261 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Azole resistance in Aspergillus: A growing public health menace

Denning, D. W. & Perlin, D. S., Nov 1 2011, In : Future Microbiology. 6, 11, p. 1229-1232 4 p.

Research output: Contribution to journalReview article

70 Scopus citations

Clinical breakpoints for the echinocandins and Candida revisited: Integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria

Pfaller, M. A., Diekema, D. J., Andes, D., Arendrup, M. C., Brown, S. D., Lockhart, S. R., Motyl, M. & Perlin, D. S., Jun 1 2011, In : Drug Resistance Updates. 14, 3, p. 164-176 13 p.

Research output: Contribution to journalArticle

259 Scopus citations

Current perspectives on echinocandin class drugs

Perlin, D. S., Apr 1 2011, In : Future Microbiology. 6, 4, p. 441-457 17 p.

Research output: Contribution to journalReview article

127 Scopus citations

Disseminated candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin

Slater, J. L., Howard, S. J., Sharp, A., Goodwin, J., Gregson, L. M., Alastruey-Izquierdo, A., Arendrup, M. C., Warn, P. A., Perlin, D. S. & Hope, W. W., Jul 1 2011, In : Antimicrobial agents and chemotherapy. 55, 7, p. 3075-3083 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Echinocandin-resistant Candida: Molecular methods and phenotypes

Perlin, D. S., Sep 1 2011, In : Current Fungal Infection Reports. 5, 3, p. 113-119 7 p.

Research output: Contribution to journalReview article

15 Scopus citations

Echinocandin susceptibility testing of Candida spp. using EUCAST EDef 7.1 and CLSI M27-A3 standard procedures: Analysis of the influence of bovine serum albumin supplementation, storage time, and drug lots

Arendrup, M. C., Rodriguez-Tudela, J. L., Park, S., Garcia-Effron, G., Delmas, G., Cuenca-Estrella, M., Gomez-Lopez, A. & Perlin, D. S., Apr 1 2011, In : Antimicrobial agents and chemotherapy. 55, 4, p. 1580-1587 8 p.

Research output: Contribution to journalArticle

42 Scopus citations
14 Scopus citations

Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance

Ben-Ami, R., Garcia-Effron, G., Lewis, R. E., Gamarra, S., Leventakos, K., Perlin, D. S. & Kontoyiannis, D. P., Aug 15 2011, In : Journal of Infectious Diseases. 204, 4, p. 626-635 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

High-frequency triazole resistance found in nonculturable aspergillus fumigatus from lungs of patients with chronic fungal disease

Denning, D. W., Park, S., Lass-Florl, C., Fraczek, M. G., Kirwan, M., Gore, R., Smith, J., Bueid, A., Moore, C. B., Bowyer, P. & Perlin, D. S., May 1 2011, In : Clinical Infectious Diseases. 52, 9, p. 1123-1129 7 p.

Research output: Contribution to journalArticle

211 Scopus citations
26 Scopus citations

In vitro activities of anidulafungin and other antifungal agents against biofilms formed by clinical isolates of different Candida and Aspergillus species

Fiori, B., Posteraro, B., Torelli, R., Tumbarello, M., Perlin, D. S., Fadda, G. & Sanguinetti, M., Jun 1 2011, In : Antimicrobial agents and chemotherapy. 55, 6, p. 3031-3035 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Multicenter, prospective clinical evaluation of respiratory samples from subjects at risk for Pneumocystis jirovecii infection by use of a commercial real-time PCR assay

Hauser, P. M., Bille, J., Lass-Flörl, C., Geltner, C., Feldmesser, M., Levi, M., Patel, H., Muggia, V., Alexander, B., Hughes, M., Follett, S. A., Cui, X., Leung, F., Morgan, G., Moody, A., Perlin, D. S. & Denning, D. W., May 2011, In : Journal of clinical microbiology. 49, 5, p. 1872-1878 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Pharmacodynamics of echinocandins against Candida glabrata: Requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts

Howard, S. J., Livermore, J., Sharp, A., Goodwin, J., Gregson, L., Alastruey-Izquierdo, A., Perlin, D. S., Warn, P. A. & Hope, W. W., Oct 2011, In : Antimicrobial agents and chemotherapy. 55, 10, p. 4880-4887 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Profiling the Aspergillus fumigatus proteome in response to caspofungin

Cagas, S. E., Jain, M. R., Li, H. & Perlin, D. S., Jan 2011, In : Antimicrobial agents and chemotherapy. 55, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

The proteomic signature of Aspergillus fumigatus during early development

Cagas, S. E., Jain, M. R., Li, H. & Perlin, D. S., Nov 1 2011, In : Molecular and Cellular Proteomics. 10, 11

Research output: Contribution to journalArticle

25 Scopus citations

Two major inositol transporters and their role in cryptococcal virulence

Wang, Y., Liu, T. B., Delmas, G., Park, S., Perlin, D. & Xue, C., May 1 2011, In : Eukaryotic Cell. 10, 5, p. 618-628 11 p.

Research output: Contribution to journalArticle

25 Scopus citations
2010

2009 H1N1 influenza infection in cancer patients and hematopoietic stem cell transplant recipients

Redelman-Sidi, G., Sepkowitz, K. A., Huang, C. K., Park, S., Stiles, J., Eagan, J., Perlin, D. S., Pamer, E. G. & Kamboj, M., Apr 1 2010, In : Journal of Infection. 60, 4, p. 257-263 7 p.

Research output: Contribution to journalArticle

83 Scopus citations