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Fingerprint Dive into the research topics where Edward Arnold is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
HIV-1 Medicine & Life Sciences
RNA-Directed DNA Polymerase Medicine & Life Sciences
Reverse Transcriptase Inhibitors Medicine & Life Sciences
Rhinovirus Medicine & Life Sciences
Mutation Medicine & Life Sciences
Ribonuclease H Medicine & Life Sciences
Nucleosides Medicine & Life Sciences
Rilpivirine Medicine & Life Sciences

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Projects 1982 2024

HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance

Arnold, E., Elder, J., Griffin, P. R., Parniak, M., Lyumkis, D., Engelman, A. N., Arnold, E., Kvaratskhelia, M., Torbett, B. E., Levy, R., Fokin, V., Jones, R., Sarafianos, S., Sharpless, K. B., Marcotrigiano, J., Stout, C. D., Olson, A. J., Torbett, B. E. & Sarafianos, S.

National Institutes of Health

9/1/128/31/22

Project: Research project

HIV
Life Cycle Stages
Human Immunodeficiency Virus Proteins
Polyproteins
Synthetic Biology

HIV Interactions In Viral Evolution

Arnold, E., Levy, R., Olson, A. J., Griffin, P. R., Lyumkis, D., Engelman, A. N., Sarafianos, S., Kvaratskhelia, M., Torbett, B. E. & Sarafianos, S.

National Institutes of Health

9/1/128/31/22

Project: Research project

Screening
X rays
Endonucleases
Crystals
Biochemistry
HIV Reverse Transcriptase
Reverse Transcriptase Inhibitors
Ribonuclease H
etravirine
Nucleic Acids
Endonucleases
Drug Delivery Systems
Human Influenza
Antiviral Agents
Fluorescence

Research Output 1979 2020

Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance

Xavier RUIZ, F. & Arnold, E., Apr 2020, In : Current Opinion in Structural Biology. 61, p. 113-123 11 p.

Research output: Contribution to journalReview article

RNA-Directed DNA Polymerase
HIV
Investigational Drugs
Human immunodeficiency virus 1 reverse transcriptase
Life Cycle Stages
1 Citation (Scopus)

Alpha-carboxynucleoside phosphonates: Direct-acting inhibitors of viral DNA polymerases

Balzarini, J., Ford, A., Maguire, N. M., John, J., Das, K., Arnold, E., Dehaen, W. & Maguire, A., Jan 2019, In : Future Medicinal Chemistry. 11, 2, p. 137-154 18 p.

Research output: Contribution to journalReview article

Nucleic Acid Synthesis Inhibitors
Organophosphonates
Viral DNA
DNA-Directed DNA Polymerase
Nucleosides

Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease

Sagong, H. Y., Bauman, J. D., Nogales, A., Martínez-Sobrido, L., Arnold, E. & LaVoie, E. J., Jun 18 2019, In : ChemMedChem. 14, 12, p. 1204-1223 20 p.

Research output: Contribution to journalArticle

Endonucleases
Human Influenza
Influenza A virus
Viruses
Bimetals

Epistasis and entrenchment of drug resistance in HIV-1 subtype B

Biswas, A., Haldane, A., Arnold, E. & Levy, R. M., Oct 2019, In : eLife. 8, e50524.

Research output: Contribution to journalArticle

Open Access
Drug Resistance
HIV-1
Mutation
Pharmaceutical Preparations
Drug therapy

Michael G. Rossmann (1930-2019)

Wu, H. & Arnold, E., Aug 1 2019, In : Nature structural & molecular biology. 26, 8, p. 660-662 3 p.

Research output: Contribution to journalArticle

Open Access