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Fingerprint Dive into the research topics where Edward Arnold is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Projects

HIV Interactions In Viral Evolution

Arnold, E., Levy, R., Olson, A. J., Griffin, P. R., Lyumkis, D., Engelman, A. N., Sarafianos, S., Kvaratskhelia, M., Torbett, B. E. & Sarafianos, S.

National Institutes of Health

9/1/128/31/22

Project: Research project

  • HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance

    Arnold, E., Elder, J., Griffin, P. R., Parniak, M., Lyumkis, D., Engelman, A. N., Arnold, E., Kvaratskhelia, M., Torbett, B. E., Levy, R., Fokin, V., Jones, R., Sarafianos, S., Sharpless, K. B., Marcotrigiano, J., Stout, C. D., Olson, A. J., Torbett, B. E. & Sarafianos, S.

    National Institutes of Health

    9/1/128/31/22

    Project: Research project

  • Research Output

    Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel

    Kang, D., Ruiz, F. X., Feng, D., Pilch, A., Zhao, T., Wei, F., Wang, Z., Sun, Y., Fang, Z., De Clercq, E., Pannecouque, C., Arnold, E., Liu, X. & Zhan, P., Feb 13 2020, In : Journal of medicinal chemistry. 63, 3, p. 1298-1312 15 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance

    Xavier RUIZ, F. & Arnold, E., Apr 2020, In : Current Opinion in Structural Biology. 61, p. 113-123 11 p.

    Research output: Contribution to journalReview article

  • Alpha-carboxynucleoside phosphonates: Direct-acting inhibitors of viral DNA polymerases

    Balzarini, J., Ford, A., Maguire, N. M., John, J., Das, K., Arnold, E., Dehaen, W. & Maguire, A., Jan 2019, In : Future Medicinal Chemistry. 11, 2, p. 137-154 18 p.

    Research output: Contribution to journalReview article

  • 1 Scopus citations

    Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease

    Sagong, H. Y., Bauman, J. D., Nogales, A., Martínez-Sobrido, L., Arnold, E. & LaVoie, E. J., Jun 18 2019, In : ChemMedChem. 14, 12, p. 1204-1223 20 p.

    Research output: Contribution to journalArticle

  • Epistasis and entrenchment of drug resistance in HIV-1 subtype B

    Biswas, A., Haldane, A., Arnold, E. & Levy, R. M., Oct 2019, In : eLife. 8, e50524.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations