Projects per year
Fingerprint Dive into the research topics where Edward Arnold is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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HIV-1
Medicine & Life Sciences
RNA-Directed DNA Polymerase
Medicine & Life Sciences
Reverse Transcriptase Inhibitors
Medicine & Life Sciences
Rhinovirus
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Ribonuclease H
Medicine & Life Sciences
Nucleosides
Medicine & Life Sciences
Rilpivirine
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1982 2024
HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance
Arnold, E., Elder, J., Griffin, P. R., Parniak, M., Lyumkis, D., Engelman, A. N., Arnold, E., Kvaratskhelia, M., Torbett, B. E., Levy, R., Fokin, V., Jones, R., Sarafianos, S., Sharpless, K. B., Marcotrigiano, J., Stout, C. D., Olson, A. J., Torbett, B. E. & Sarafianos, S.
9/1/12 → 8/31/22
Project: Research project
HIV
Life Cycle Stages
Human Immunodeficiency Virus Proteins
Polyproteins
Synthetic Biology
HIV Interactions In Viral Evolution
Arnold, E., Levy, R., Olson, A. J., Griffin, P. R., Lyumkis, D., Engelman, A. N., Sarafianos, S., Kvaratskhelia, M., Torbett, B. E. & Sarafianos, S.
9/1/12 → 8/31/22
Project: Research project
Screening
X rays
Endonucleases
Crystals
Biochemistry
HIV Reverse Transcriptase
Reverse Transcriptase Inhibitors
Ribonuclease H
etravirine
Nucleic Acids
Drug development targeting influenza A cap-snatching endonuclease
7/1/15 → 6/30/17
Project: Research project
Endonucleases
Drug Delivery Systems
Human Influenza
Antiviral Agents
Fluorescence
Research Output 1979 2020
Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance
Xavier RUIZ, F. & Arnold, E., Apr 2020, In : Current Opinion in Structural Biology. 61, p. 113-123 11 p.Research output: Contribution to journal › Review article
RNA-Directed DNA Polymerase
HIV
Investigational Drugs
Human immunodeficiency virus 1 reverse transcriptase
Life Cycle Stages
1
Citation
(Scopus)
Alpha-carboxynucleoside phosphonates: Direct-acting inhibitors of viral DNA polymerases
Balzarini, J., Ford, A., Maguire, N. M., John, J., Das, K., Arnold, E., Dehaen, W. & Maguire, A., Jan 2019, In : Future Medicinal Chemistry. 11, 2, p. 137-154 18 p.Research output: Contribution to journal › Review article
Nucleic Acid Synthesis Inhibitors
Organophosphonates
Viral DNA
DNA-Directed DNA Polymerase
Nucleosides
Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease
Sagong, H. Y., Bauman, J. D., Nogales, A., Martínez-Sobrido, L., Arnold, E. & LaVoie, E. J., Jun 18 2019, In : ChemMedChem. 14, 12, p. 1204-1223 20 p.Research output: Contribution to journal › Article
Endonucleases
Human Influenza
Influenza A virus
Viruses
Bimetals
Epistasis and entrenchment of drug resistance in HIV-1 subtype B
Biswas, A., Haldane, A., Arnold, E. & Levy, R. M., Oct 2019, In : eLife. 8, e50524.Research output: Contribution to journal › Article
Open Access
Drug Resistance
HIV-1
Mutation
Pharmaceutical Preparations
Drug therapy
Michael G. Rossmann (1930-2019)
Wu, H. & Arnold, E., Aug 1 2019, In : Nature structural & molecular biology. 26, 8, p. 660-662 3 p.Research output: Contribution to journal › Article
Open Access