Projects per year
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- 14 Similar Profiles
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Projects
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HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance
Arnold, E., Elder, J., Griffin, P. R., Parniak, M., Lyumkis, D., Engelman, A. N., Arnold, E., Kvaratskhelia, M., Torbett, B. E., Levy, R., Fokin, V., Jones, R., Sarafianos, S., Sharpless, K. B., Marcotrigiano, J., Stout, C. D., Olson, A. J., Torbett, B. E. & Sarafianos, S.
9/1/12 → 8/31/22
Project: Research project
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HIV Interactions In Viral Evolution
Arnold, E., Levy, R., Olson, A. J., Griffin, P. R., Lyumkis, D., Engelman, A. N., Sarafianos, S., Kvaratskhelia, M., Torbett, B. E. & Sarafianos, S.
9/1/12 → 8/31/22
Project: Research project
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Drug development targeting influenza A cap-snatching endonuclease
7/1/15 → 6/30/17
Project: Research project
Research Output
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Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase
Nguyen, P. D. M., Zheng, J., Gremminger, T. J., Qiu, L., Zhang, D., Tuske, S., Lange, M. J., Griffin, P. R., Arnold, E., Chen, S. J., Zou, X., Heng, X. & Burke, D. H., Mar 18 2020, In: Nucleic acids research. 48, 5, p. 2709-2722 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel
Kang, D., Ruiz, F. X., Feng, D., Pilch, A., Zhao, T., Wei, F., Wang, Z., Sun, Y., Fang, Z., De Clercq, E., Pannecouque, C., Arnold, E., Liu, X. & Zhan, P., Feb 13 2020, In: Journal of medicinal chemistry. 63, 3, p. 1298-1312 15 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance
Xavier RUIZ, F. & Arnold, E., Apr 2020, In: Current Opinion in Structural Biology. 61, p. 113-123 11 p.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
Non-nucleoside reverse transcriptase inhibitors join forces with integrase inhibitors to combat HIV
Himmel, D. M. & Arnold, E., Jun 2020, In: Pharmaceuticals. 13, 6, p. 1-26 26 p., 122.Research output: Contribution to journal › Review article › peer-review
Open Access -
Alpha-carboxynucleoside phosphonates: Direct-acting inhibitors of viral DNA polymerases
Balzarini, J., Ford, A., Maguire, N. M., John, J., Das, K., Arnold, E., Dehaen, W. & Maguire, A., Jan 2019, In: Future Medicinal Chemistry. 11, 2, p. 137-154 18 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations