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Fernando Muzzio

  • 9102 Citations
  • 54 h-Index
1988 …2019
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  • 6 Similar Profiles
Powders Chemical Compounds
Drug products Engineering & Materials Science
Pharmaceutical Preparations Chemical Compounds
Tablets Medicine & Life Sciences
Stretching Engineering & Materials Science
Residence time distribution Chemical Compounds
Granular materials Engineering & Materials Science
Finite difference method Chemical Compounds

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Projects 2015 2018

Real Time Release In Continuous Solid Dose Manufacturing: Systematic Characterization Of Material Properties, And Optimal Design Of Sensing And Control Methods

Muzzio, F.

FDA

9/15/15 → 8/31/18

Project: Research project

Materials properties
Drug products
Control systems
Industry
Optimal design

Research Output 1988 2019

2 Citations (Scopus)

A comprehensive analysis and optimization of continuous twin-screw granulation processes via sequential experimentation strategy

Meng, W., Rao, K. S., Snee, R. D., Ramachandran, R. & Muzzio, F., Feb 10 2019, In : International Journal of Pharmaceutics. 556, p. 349-362 14 p.

Research output: Contribution to journal › Article

Tablets
Temperature
Tensile Strength
Porosity
Caffeine

Advanced process design and understanding of continuous twin-screw granulation via implementation of in-line process analytical technologies

Meng, W., Román-Ospino, A. D., Panikar, S. S., O'Callaghan, C., Gilliam, S. J., Ramachandran, R. & Muzzio, F., Apr 1 2019, In : Advanced Powder Technology. 30, 4, p. 879-894 16 p.

Research output: Contribution to journal › Article

Granulation
Process design
Near infrared spectroscopy
Raman spectroscopy
Granulators
2 Citations (Scopus)

Assessment of blend uniformity in a continuous tablet manufacturing process

Sierra-Vega, N. O., Román-Ospino, A., Scicolone, J., Muzzio, F., Romañach, R. J. & Méndez, R., Apr 5 2019, In : International Journal of Pharmaceutics. 560, p. 322-333 12 p.

Research output: Contribution to journal › Article

Tablets
Pharmaceutical Preparations
Selection Bias
Drug Monitoring
Acetaminophen

A “Large-N” Content Uniformity Process Analytical Technology (PAT) Method for Phenytoin Sodium Tablets

Pawar, P., Talwar, S., Reddy, D., Bandi, C. K., Wu, H., Sowrirajan, K., Friedman, R., Drazer, G., Drennen, J. K. & Muzzio, F., Jan 1 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 494-505 12 p.

Research output: Contribution to journal › Article

Phenytoin
Tablets
Technology
Least-Squares Analysis
Sample Size

Continuous high-shear granulation: Mechanistic understanding of the influence of process parameters on critical quality attributes via elucidating the internal physical and chemical microstructure

Meng, W., Dvořák, J., Kumar, R., Hofmeister, R., Štěpánek, F., Ramachandran, R. & Muzzio, F., Sep 1 2019, In : Advanced Powder Technology. 30, 9, p. 1765-1781 17 p.

Research output: Contribution to journal › Article

Granulators
Granulation
Tablets
Microstructure
Disintegration