Projects per year
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Gut-liver crosstalk by FGF15/19 in regulating xenobiotic nuclear receptor activation
National Institute of General Medical Sciences
7/1/20 → 4/30/22
Project: Research project
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Differential roles of FXR and FGF15 in liver fibrosis development
National Institute of Environmental Health Sciences
4/1/18 → 3/31/21
Project: Research project
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Gut bile acids, Fxr, & Fgf15 in total parenteral nutrition-associated cholestasis
National Institute of General Medical Sciences
7/5/13 → 5/31/18
Project: Research project
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FXR, nuclear receptors, and transcriptional regulation of liver homeostasis
National Institute of Diabetes and Digestive and Kidney Diseases
9/26/11 → 8/31/13
Project: Research project
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Tissue specific mechanism of FXR in suppressing bile-acid synthesis
National Institute of Diabetes and Digestive and Kidney Diseases
6/10/08 → 5/31/13
Project: Research project
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Bile Acid Profiling in Mouse Biofluids and Tissues
Kong, B., Rizzolo, D., Taylor, R. E. & Guo, G. L., 2022, In: Methods in molecular biology (Clifton, N.J.). 2455, p. 305-318 14 p.Research output: Contribution to journal › Article › peer-review
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Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
Rizzolo, D., Kong, B., Piekos, S., Chen, L., Zhong, X., Lu, J., Shi, J., Zhu, H. J., Yang, Q., Li, A., Li, L., Wang, H., Siemiątkowska, A., Park, C., Kagan, L. & Guo, G., Apr 1 2022, In: Drug Metabolism and Disposition. 50, 4, p. 468-477 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Suppression of Bile Acid Synthesis in a Preterm Infant Receiving Prolonged Parenteral Nutrition
Memon, N., Lee, C. W., Herdt, A., Weinberger, B. I., Hegyi, T., Carayannopoulos, M. O., Aleksunes, L. M., Guo, G. L. & Griffin, I. J., Jan 1 2022, In: Journal of Clinical and Experimental Hepatology. 12, 1, p. 200-203 4 p.Research output: Contribution to journal › Article › peer-review
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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
Wang, H., Brown, P. C., Chow, E. C. Y., Ewart, L., Ferguson, S. S., Fitzpatrick, S., Freedman, B. S., Guo, G. L., Hedrich, W., Heyward, S., Hickman, J., Isoherranen, N., Li, A. P., Liu, Q., Mumenthaler, S. M., Polli, J., Proctor, W. R., Ribeiro, A., Wang, J. Y., Wange, R. L. & 1 others, , Sep 2021, In: Clinical and translational science. 14, 5, p. 1659-1680 22 p.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
Bile acid homeostasis in female mice deficient in Cyp7a1 and Cyp27a1
Rizzolo, D., Kong, B., Taylor, R. E., Brinker, A., Goedken, M., Buckley, B. & Guo, G. L., Dec 2021, In: Acta Pharmaceutica Sinica B. 11, 12, p. 3847-3856 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations