• 5947 Citations
  • 39 h-Index
1974 …2024

Research output per year

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Research Output

2019

Green Tea Polyphenols Modify the Gut Microbiome in db/db Mice as Co-Abundance Groups Correlating with the Blood Glucose Lowering Effect

Chen, T., Liu, A. B., Sun, S., Ajami, N. J., Ross, M. C., Wang, H., Zhang, L., Reuhl, K., Kobayashi, K., Onishi, J. C., Zhao, L. & Yang, C. S., Apr 2019, In : Molecular Nutrition and Food Research. 63, 8, 1801064.

Research output: Contribution to journalArticle

10 Scopus citations
2018

Green Tea Polyphenol EGCG Alleviates Metabolic Abnormality and Fatty Liver by Decreasing Bile Acid and Lipid Absorption in Mice

Huang, J., Feng, S., Liu, A., Dai, Z., Wang, H., Reuhl, K., Lu, W. & Yang, C. S., Feb 1 2018, In : Molecular Nutrition and Food Research. 62, 4, 1700696.

Research output: Contribution to journalArticle

22 Scopus citations

Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet

Feng, S., Dai, Z., Liu, A. B., Huang, J., Narsipur, N., Guo, G., Kong, B., Reuhl, K., Lu, W., Luo, Z. & Yang, C. S., Oct 2018, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1863, 10, p. 1274-1284 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
4 Scopus citations

The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Na v 1.6

Hossain, M. M., Weig, B., Reuhl, K., Gearing, M., Wu, L-J. & Richardson, J. R., Oct 2018, In : Experimental Neurology. 308, p. 111-119 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

A Basic ApoE-Based Peptide Mediator to Deliver Proteins across the Blood-Brain Barrier: Long-Term Efficacy, Toxicity, and Mechanism

Meng, Y., Wiseman, J. A., Nemtsova, Y., Moore, D., Guevarra, J., Reuhl, K., Banks, W. A., Daneman, R., Sleat, D. E. & Lobel, P., Jul 5 2017, In : Molecular Therapy. 25, 7, p. 1531-1543 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s)

Garbuzenko, O. B., Ivanova, V., Kholodovych, V., Reimer, D. C., Reuhl, K. R., Yurkow, E., Adler, D. & Minko, T., Aug 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 6, p. 1983-1992 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

PhIP/DSS-induced colon carcinogenesis in CYP1A-humanized mice and the possible role of Lgr5+ stem cells

Chen, J. X., Wang, H., Liu, A., Zhang, L., Reuhl, K. & Yang, C. S., Jan 1 2017, In : Toxicological Sciences. 155, 1, p. 224-233 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

δ- and γ-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages

Chen, J. X., Liu, A., Lee, M. J., Wang, H., Yu, S., Chi, E., Reuhl, K., Suh, N. & Yang, C. S., Jan 1 2017, In : Molecular Carcinogenesis. 56, 1, p. 172-183 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
2016

Concerted action of IFN-α and IFN-γ induces local NK cell immunity and halts cancer growth

Lasfar, A., de la Torre, A., Abushahba, W., Cohen-Solal, K. A., Castaneda, I., Yuan, Y., Reuhl, K., Zloza, A., Raveche, E., Laskin, D. L. & Kotenko, S. V., Jan 1 2016, In : Oncotarget. 7, 31, p. 49259-49267 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Dietary tocopherols inhibit PhIP-induced prostate carcinogenesis in CYP1A-humanized mice

Chen, J. X., Li, G., Wang, H., Liu, A., Lee, M. J., Reuhl, K., Suh, N., Bosland, M. C. & Yang, C. S., Feb 1 2016, In : Cancer Letters. 371, 1, p. 71-78 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

EphA5 and EphA6: Regulation of neuronal and spine morphology

Das, G., Yu, Q., Hui, R., Reuhl, K., Gale, N. W. & Zhou, R., Aug 2 2016, In : Cell and Bioscience. 6, 1, 48.

Research output: Contribution to journalArticle

6 Scopus citations

Trimethyltin intoxication induces the migration of ventricular/subventricular zone cells to the injured murine hippocampus

Weig, B. C., Richardson, J. R., Lowndes, H. E. & Reuhl, K. R., May 1 2016, In : Neurotoxicology. 54, p. 72-80 9 p.

Research output: Contribution to journalArticle

2015

Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells

Teh, J. L. F., Shah, R., La Cava, S., Dolfi, S. C., Mehta, M. S., Kongara, S., Price, S., Ganesan, S., Reuhl, K. R., Hirshfield, K. M., Karantza, V. & Chen, S., May 1 2015, In : Breast Cancer Research and Treatment. 151, 1, p. 57-73 17 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Critical role of the endogenous interferon ligand-receptors in type I and type II interferons response

Lasfar, A., Cook, J. R., Cohen Solal, K. A., Reuhl, K., Kotenko, S. V., Langer, J. A. & Laskin, D. L., Jul 2014, In : Immunology. 142, 3, p. 442-452 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effective intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain

Meng, Y., Sohar, I., Sleat, D. E., Richardson, J. R., Reuhl, K., Jenkins, R. B., Sarkar, G. & Lobel, P., Mar 2014, In : Molecular Therapy. 22, 3, p. 547-553 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Novel cystine ester mimics for the treatment of cystinuria-induced urolithiasis in a knockout mouse model

Sahota, A., Parihar, J. S., Capaccione, K. M., Yang, M., Noll, K., Gordon, D., Reimer, D., Yang, I., Buckley, B. T., Polunas, M., Reuhl, K. R., Lewis, M. R., Ward, M. D., Goldfarb, D. S. & Tischfield, J. A., Nov 1 2014, In : Urology. 84, 5, p. 1249.e9-1249.e15

Research output: Contribution to journalArticle

10 Scopus citations
2013

Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia

Smolarek, A. K., So, J. Y., Thomas, P. E., Lee, H. J., Paul, S., Dombrowski, A., Wang, C. X., Saw, C. L. L., Khor, T. O., Kong, A. N. T., Reuhl, K., Lee, M. J., Yang, C. S. & Suh, N., Jul 1 2013, In : Molecular Carcinogenesis. 52, 7, p. 514-525 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Erratum: U1 adaptor oligonucleotides targeting BCL2 and GRM1 suppress growth of human melanoma xenografts in vivo (Molecular Therapy - Nucleic Acids (2013) 2 (e111) DOI: 10.1038/mtna.2013.44)

Goraczniak, R., Wall, B. A., Behlke, M. A., Lennox, K. A., Ho, E. S., Zaphiros, N. H., Jakubowski, C., Patel, N. R., Zhao, S., Magaway, C., Subbie, S. A., Yu, L. J., LaCava, S., Reuhl, K. R., Chen, S. & Gunderson, S. I., Jul 29 2013, In : Molecular Therapy - Nucleic Acids. 2, e111.

Research output: Contribution to journalComment/debate

Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2

Ivanova, V., Garbuzenko, O. B., Reuhl, K. R., Reimer, D. C., Pozharov, V. P. & Minko, T., Jun 1 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 84, 2, p. 335-344 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a, h]anthracene

Chang, R. L., Wood, A. W., Huang, M. T., Xie, J. G., Cui, X. X., Reuhl, K. R., Boyd, D. R., Lin, Y., Shih, W. J., Balani, S. K., Yagi, H., Jerina, D. M. & Conney, A. H., Sep 1 2013, In : Carcinogenesis. 34, 9, p. 2184-2191 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

The golgi-cox method

Das, G., Reuhl, K. & Zhou, R., Sep 4 2013, Neural Development: Methods and Protocols. p. 313-321 9 p. (Methods in Molecular Biology; vol. 1018).

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Scopus citations

U1 Adaptor oligonucleotides targeting BCL2 and GRM1 suppress growth of human melanoma xenografts in vivo

Goraczniak, R., Wall, B. A., Behlke, M. A., Lennox, K. A., Ho, E. S., Zaphiros, N. H., Jakubowski, C., Patel, N. R., Zhao, S., Magaway, C., Subbie, S. A., Yu, L. J., LaCava, S., Reuhl, K., Chen, S. & Gunderson, S., Jan 1 2013, In : Molecular Therapy - Nucleic Acids. 2, p. e92 e92.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer

Smolarek, A. K., So, J. Y., Burgess, B., Kong, A. N. T., Reuhl, K., Lin, Y., Shih, W. J., Li, G., Lee, M. J., Chen, Y. K., Yang, C. S. & Suh, N., Nov 1 2012, In : Cancer Prevention Research. 5, 11, p. 1310-1320 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice

Li, G., Wang, H., Liu, A. B., Cheung, C., Reuhl, K. R., Bosland, M. C. & Yang, C. S., Jul 1 2012, In : Cancer Prevention Research. 5, 7, p. 963-972 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Polychlorinated biphenyl congeners that increase the glucuronidation and biliary excretion of thyroxine are distinct from the congeners that enhance the serum disappearance of thyroxine

Martin, L. A., Wilson, D. T., Reuhl, K. R., Gallo, M. A. & Klaassen, C. D., Mar 1 2012, In : Drug Metabolism and Disposition. 40, 3, p. 588-595 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Two-in-one: Combined targeted chemo and gene therapy for tumor suppression and prevention of metastases

Zhang, M., Garbuzenko, O. B., Reuhl, K., Rodriguez-Rust, L. & Minko, T., Feb 1 2012, In : Nanomedicine. 7, 2, p. 185-197 13 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice

Chen, Y. K., Cheung, C., Reuhl, K., Liu, A. B., Lee, M. J., Lu, Y. P. & Yang, C., Nov 9 2011, In : Journal of agricultural and food chemistry. 59, 21, p. 11862-11871 10 p.

Research output: Contribution to journalArticle

114 Scopus citations

Role of oxidative stress and the mitochondrial permeability transition in methylmercury cytotoxicity

Polunas, M., Halladay, A., Tjalkens, R. B., Philbert, M. A., Lowndes, H. & Reuhl, K., Oct 1 2011, In : Neurotoxicology. 32, 5, p. 526-534 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Transplantation of β-endorphin neurons into the hypothalamus promotes immune function and restricts the growth and metastasis of mammary carcinoma

Sarkar, D. K., Zhang, C., Murugan, S., Dokur, M., Boyadjieva, N. I., Ortigüela, M., Reuhl, K. R. & Mojtehedzadeh, S., Oct 1 2011, In : Cancer Research. 71, 19, p. 6282-6291 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Unifying mechanisms of neurological disorders--scientific, translational and clinical implications: overview and theme of the 26th International Neurotoxicology Conference.

Cranmer, J. M., Reuhl, K. R., Richardson, J. R. & Lang, L. A., Oct 2011, In : Neurotoxicology. 32, 5, p. 499-501 3 p.

Research output: Contribution to journalEditorial

2010

Antitumor activity of Type i and Type III interferons in BNL hepatoma model

Abushahba, W., Balan, M., Castaneda, I., Yuan, Y., Reuhl, K., Raveche, E., De La Torre, A., Lasfar, A. & Kotenko, S. V., Jul 1 2010, In : Cancer Immunology, Immunotherapy. 59, 7, p. 1059-1071 13 p.

Research output: Contribution to journalArticle

61 Scopus citations

Cytoskeletal Elements in Neurotoxicity

Pyle, S. J. & Reuhl, K., Aug 12 2010, Nervous System and Behavioral Toxicology. Elsevier Inc., Vol. 13. p. 71-87 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Dietary phenethylisothiocyanate attenuates bowel inflammation in mice

Dey, M., Kuhn, P., Ribnicky, D., Premkumar, V., Reuhl, K. & Raskin, I., Apr 28 2010, In : BMC Chemical Biology. 10, 4.

Research output: Contribution to journalArticle

21 Scopus citations

Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats

Polanco, T. A., Crismale-Gann, C., Reuhl, K. R., Sarkar, D. K. & Cohick, W. S., Nov 1 2010, In : Alcoholism: Clinical and Experimental Research. 34, 11, p. 1879-1887 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice

Lambert, J. D., Kennett, M. J., Sang, S., Reuhl, K., Ju, J. & Yang, C., Jan 1 2010, In : Food and Chemical Toxicology. 48, 1, p. 409-416 8 p.

Research output: Contribution to journalArticle

226 Scopus citations
103 Scopus citations

Mixed tocotrienols inhibit prostate carcinogenesis in TRAMP mice

Barve, A., Khor, T. O., Reuhl, K., Reddy, B., Newmark, H. & Kong, A. N., Aug 1 2010, In : Nutrition and Cancer. 62, 6, p. 789-794 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
2009

Autism and oxidative stress: Evidence from an animal model

Cheh, M. A., Halladay, A. K., Yochum, C. L., Reuhl, K. R., Polunas, M., Ming, X. & Wagner, G. C., Jan 1 2009, Autism: Oxidative Stress, Inflammation, and Immune Abnormalities. CRC Press, p. 131-152 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Effect of α-tocopherol, n-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model

Jing, H., Bin, Z., Ba, L., Maojung, L., Xingpei, H., Reuhl, K. R., Xiaoxin, C. & Chung, S. Y., Mar 15 2009, In : International Journal of Cancer. 124, 6, p. 1270-1275 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

γ-Tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice

Barve, A., Khor, T. O., Nair, S., Reuhl, K., Suh, N., Reddy, B., Newmark, H. & Kong, A. N., Apr 1 2009, In : International Journal of Cancer. 124, 7, p. 1693-1699 7 p.

Research output: Contribution to journalArticle

95 Scopus citations
2008

Cyclic adenosine monophosphate differentiated β-endorphin neurons promote immune function and prevent prostate cancer growth

Sarkar, D., Boyadjieva, N. I., Cui, P. C., Ortigüela, M., Reuhl, K., Clement, E. M., Kuhn, P. & Marano, J., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9105-9110 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats

Mesia-Vela, S., Sanchez, R. I., Roberts, K. G., Reuhl, K. R., Conney, A. H. & Kauffman, F. C., Apr 3 2008, In : Toxicology. 246, 1, p. 63-72 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice

Bose, M., Lambert, J. D., Ju, J., Reuhl, K. R., Shapses, S. A. & Yang, C. S., Sep 1 2008, In : Journal of Nutrition. 138, 9, p. 1677-1683 7 p.

Research output: Contribution to journalArticle

401 Scopus citations

VPA-induced apoptosis and behavioral deficits in neonatal mice

Yochum, C. L., Dowling, P., Reuhl, K. R., Wagner, G. C. & Ming, X., Apr 8 2008, In : Brain research. 1203, p. 126-132 7 p.

Research output: Contribution to journalArticle

62 Scopus citations
2007

Behavioral and neurochemical sensitization to amphetamine following early postnatal administration of methylmercury (MeHg)

Wagner, G., Reuhl, K., Ming, X. & Halladay, A. K., Jan 1 2007, In : Neurotoxicology. 28, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2006

A new neurobehavioral model of autism in mice: Pre- and postnatal exposure to sodium valproate

Wagner, G. C., Reuhl, K. R., Cheh, M., McRae, P. & Halladay, A. K., Aug 1 2006, In : Journal of Autism and Developmental Disorders. 36, 6, p. 779-793 15 p.

Research output: Contribution to journalArticle

154 Scopus citations

Characterization of the mouse IFN-λ ligand-receptor system: IFN-λs exhibit antitumor activity against B16 melanoma

Lasfar, A., Lewis-Antes, A., Smirnov, S. V., Anantha, S., Abushahba, W., Tian, B., Reuhl, K., Dickensheets, H., Sheikh, F., Donnelly, R. P., Raveche, E. & Kotenko, S. V., Apr 15 2006, In : Cancer Research. 66, 8, p. 4468-4477 10 p.

Research output: Contribution to journalArticle

185 Scopus citations

CYP2A13 in human respiratory tissues and lung cancers: An immunohistochemical study with a new peptide-specific antibody

Zhu, L. R., Thomas, P. E., Lu, G., Reuhl, K. R., Yang, G. Y., Wang, L. D., Wang, S. L., Yang, C. S., He, X. Y. & Hong, J. Y., Sep 27 2006, In : Drug Metabolism and Disposition. 34, 10, p. 1672-1676 5 p.

Research output: Contribution to journalArticle

58 Scopus citations
133 Scopus citations