Projects per year
Fingerprint Dive into the research topics where Konstantin Severinov is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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DNA-Directed RNA Polymerases
Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats
Medicine & Life Sciences
Escherichia coli
Medicine & Life Sciences
Bacteriophages
Medicine & Life Sciences
Bacterial RNA
Medicine & Life Sciences
DNA
Medicine & Life Sciences
Transcription
Chemical Compounds
CRISPR-Cas Systems
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1976 2021
The function of small RNA-based viral defense system in E. coli
2/1/13 → 1/31/21
Project: Research project
Clustered Regularly Interspaced Short Palindromic Repeats
Viral RNA
Escherichia coli
CRISPR-Associated Proteins
Intergenic DNA
DNA Restriction-Modification Enzymes
Protein C
Gene Expression
DNA Restriction Enzymes
Methyltransferases
Plasmids
microcin
Bacterial RNA
Genes
Amino Acids
Northeast Biodefense Center
Perlin, D., Severinov, K., Palacios, G. F., Basler, C., Alaedini, A., Fries, B., Briese, T., Rice, C., [No Value], C. R., Chave, K. J., Kielian, M., Bliska, J., Levy, D., Lipkin, W., Brady, S., Rose, J. K., García-Sastre, A., Gulcicek, E., Moscona, A., Casadevall, A., Palese, P., Califano, A., Buck, J., Belfort, M., Pei-Yong, S., Crystal, R., Scharff, M., Sturman, L., Bernard, K., Galan, J., MacKow, E. R. & Egan, C.
9/4/03 → 2/28/15
Project: Research project
Burkholderia mallei
Extensively Drug-Resistant Tuberculosis
Yersinia pestis
Animal Care Committees
Animal Models
DNA-Directed RNA Polymerases
Taq Polymerase
Thermus
Bacterial RNA
Enzymes
Research Output 1990 2019
5
Citations
(Scopus)
Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison
Ghilarov, D., Stevenson, C. E. M., Travin, D. Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D. M. & Severinov, K., Feb 21 2019, In : Molecular cell. 73, 4, p. 749-762.e5Research output: Contribution to journal › Article
Open Access
DNA Gyrase
Poisons
Ligases
Peptides
Topoisomerase Inhibitors
3
Citations
(Scopus)
Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor
Dong, S. H., Kulikovsky, A., Zukher, I., Estrada, P., Dubiley, S., Severinov, K. & Nair, S. K., Jan 1 2019, In : Chemical Science. 10, 8, p. 2391-2395 5 p.Research output: Contribution to journal › Article
Open Access
Biosynthesis
Nucleotides
Anti-Bacterial Agents
Peptides
Ubiquitin-Activating Enzymes
4
Citations
(Scopus)
BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site
Gordeeva, J., Morozova, N., Sierro, N., Isaev, A., Sinkunas, T., Tsvetkova, K., Matlashov, M., Truncaite, L., Morgan, R. D., Ivanov, N. V., Siksnys, V., Zeng, L. & Severinov, K., Jan 10 2019, In : Nucleic acids research. 47, 1, p. 253-265 13 p.Research output: Contribution to journal › Article
Bacteriophages
Methylation
Escherichia coli
DNA
CRISPR-Cas Systems
CRISPR–Cas molecular beacons as tool for studies of assembly of CRISPR–Cas effector complexes and their interactions with DNA
Mekler, V., Kuznedelov, K., Minakhin, L., Murugan, K., Sashital, D. G. & Severinov, K., Jan 1 2019, Methods in Enzymology. Bailey, S. (ed.). Academic Press Inc., p. 337-363 27 p. (Methods in Enzymology; vol. 616).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Clustered Regularly Interspaced Short Palindromic Repeats
DNA
Nucleic acid sequences
RNA
Prokaryotic Cells
6
Citations
(Scopus)
Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids
Bayfield, O. W., Klimuk, E., Winkler, D. C., Hesketh, E. L., Chechik, M., Cheng, N., Dykeman, E. C., Minakhin, L., Ranson, N. A., Severinov, K., Steven, A. C. & Antson, A. A., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3556-3561 6 p.Research output: Contribution to journal › Article
DNA Packaging
Capsid
Viruses
DNA
Product Packaging