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Fingerprint Dive into the research topics where Lauren Aleksunes is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Liver Medicine & Life Sciences
Acetaminophen Medicine & Life Sciences
Messenger RNA Medicine & Life Sciences
Kidney Medicine & Life Sciences
NF-E2-Related Factor 2 Medicine & Life Sciences
Proteins Medicine & Life Sciences
Wounds and Injuries Medicine & Life Sciences
Xenobiotics Medicine & Life Sciences

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Projects 2008 2021

experience
health science
student
science
school
Endocrine Disruptors
Pregnancy
Breast Neoplasms
Proteins
Genistein
Cisplatin
Kidney
Drug Therapy
Wounds and Injuries
Antineoplastic Agents

Research Output 2000 2019

  • 4467 Citations
  • 39 h-Index
  • 106 Article
  • 7 Review article
  • 3 Chapter
  • 1 Comment/debate
1 Citation (Scopus)

Anandamide down-regulates placental transporter expression through CB2 receptor-mediated inhibition of cAMP synthesis

Szilagyi, J. T., Composto-Wahler, G. M., Joseph, L. B., Wang, B., Rosen, T., Laskin, J. D. & Aleksunes, L. M., Mar 2019, In : Pharmacological Research. 141, p. 331-342 12 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB2
Trophoblasts
Down-Regulation
Cyclic AMP Response Element-Binding Protein
Messenger RNA
2 Citations (Scopus)

Hepatic carboxylesterases are differentially regulated in PPARα-null mice treated with perfluorooctanoic acid

Wen, X., Baker, A. A., Klaassen, C. D., Corton, J. C., Richardson, J. R. & Aleksunes, L. M., Mar 15 2019, In : Toxicology. 416, p. 15-22 8 p.

Research output: Contribution to journalArticle

perfluorooctanoic acid
Carboxylic Ester Hydrolases
Peroxisome Proliferator-Activated Receptors
Liver
Messenger RNA

Identification and characterization of efflux transporters that modulate the subtoxic disposition of diclofenac and its metabolites

Scialis, R. J., Aleksunes, L., Csanaky, I. L., Klaassen, C. D. & Manautou, J. E., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 10, p. 1080-1092 13 p.

Research output: Contribution to journalArticle

Open Access
Diclofenac
Breast Neoplasms
Knockout Mice
Proteins
Binding Sites

Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling

You, D., Wen, X., Gorczyca, L., Morris, A., Richardson, J. R. & Aleksunes, L., Oct 1 2019, In : Molecular Neurobiology. 56, 10, p. 6986-7002 17 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Histone Deacetylases
Acetylation
Histones
Endothelial Cells
4 Citations (Scopus)

Nonanimal models for acute toxicity evaluations: Applying data-driven profiling and read-across

Russo, D. P., Strickland, J., Karmaus, A. L., Wang, W., Shende, S., Hartung, T., Aleksunes, L. M. & Zhu, H., Apr 2019, In : Environmental health perspectives. 127, 4, 047001.

Research output: Contribution to journalArticle

Open Access
Biological Assay
Chemical Models
Toxicology
Cluster Analysis
Animal Models