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Fingerprint Dive into the research topics where Lauren Aleksunes is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Liver Medicine & Life Sciences
Acetaminophen Medicine & Life Sciences
Messenger RNA Medicine & Life Sciences
Kidney Medicine & Life Sciences
NF-E2-Related Factor 2 Medicine & Life Sciences
Proteins Medicine & Life Sciences
Wounds and Injuries Medicine & Life Sciences
Xenobiotics Medicine & Life Sciences

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Projects 1987 2023

Drug Disposition and Nephrotoxicity

Aleksunes, L. & Joy, M.

National Institutes of Health

9/15/187/31/22

Project: Research project

Cisplatin
Serotonin 5-HT3 Receptor Antagonists
Pharmaceutical Preparations
Acute Kidney Injury
Antiemetics

Placental Responses to Environmental Chemicals

Aleksunes, L., Barrett, E. & Dongeun, H.

National Institutes of Health

7/1/184/30/23

Project: Research project

Cadmium
Fetal Development
Placenta
Aptitude
Pregnancy

Summer Research Training in Environmental Health Sciences

Laskin, D., Aleksunes, L., Laskin, D. L. & Laskin, D.

National Institutes of Health

8/9/114/30/21

Project: Research project

experience
health science
student
science
school

TRAINING IN ENVIROMMENTAL TOXICOLOGY

Reuhl, K., Aleksunes, L., Snyder, R. & Richardson, J.

National Institutes of Health

9/1/876/30/22

Project: Research project

Ecotoxicology
graduate
Toxicology
Environmental Health
trainee
Gene-Environment Interaction
Pesticides
Parkinson Disease
Brain
P-Glycoprotein

Research Output 2000 2020

  • 4493 Citations
  • 39 h-Index
  • 106 Article
  • 7 Review article
  • 3 Chapter
  • 1 Comment/debate
1 Citation (Scopus)

Anandamide down-regulates placental transporter expression through CB2 receptor-mediated inhibition of cAMP synthesis

Szilagyi, J. T., Composto-Wahler, G. M., Joseph, L. B., Wang, B., Rosen, T., Laskin, J. D. & Aleksunes, L. M., Mar 2019, In : Pharmacological Research. 141, p. 331-342 12 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB2
Trophoblasts
Down-Regulation
Cyclic AMP Response Element-Binding Protein
Messenger RNA
2 Citations (Scopus)

Hepatic carboxylesterases are differentially regulated in PPARα-null mice treated with perfluorooctanoic acid

Wen, X., Baker, A. A., Klaassen, C. D., Corton, J. C., Richardson, J. R. & Aleksunes, L. M., Mar 15 2019, In : Toxicology. 416, p. 15-22 8 p.

Research output: Contribution to journalArticle

perfluorooctanoic acid
Carboxylic Ester Hydrolases
Peroxisome Proliferator-Activated Receptors
Liver
Messenger RNA

Identification and characterization of efflux transporters that modulate the subtoxic disposition of diclofenac and its metabolites

Scialis, R. J., Aleksunes, L. M., Csanaky, I. L., Klaassen, C. D. & Manautou, J. E., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 10, p. 1080-1092 13 p.

Research output: Contribution to journalArticle

Open Access
Diclofenac
Breast Neoplasms
Knockout Mice
Proteins
Binding Sites

Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling

You, D., Wen, X., Gorczyca, L., Morris, A., Richardson, J. R. & Aleksunes, L., Oct 1 2019, In : Molecular Neurobiology. 56, 10, p. 6986-7002 17 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Histone Deacetylases
Acetylation
Histones
Endothelial Cells
5 Citations (Scopus)

Nonanimal models for acute toxicity evaluations: Applying data-driven profiling and read-across

Russo, D. P., Strickland, J., Karmaus, A. L., Wang, W., Shende, S., Hartung, T., Aleksunes, L. M. & Zhu, H., Apr 2019, In : Environmental health perspectives. 127, 4, 047001.

Research output: Contribution to journalArticle

Open Access
Biological Assay
Chemical Models
Toxicology
Cluster Analysis
Animal Models