Luciano D'Adamio

Emailld550rutgersedu

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Trem2-mediated microglia-neuronal axis in Alzheimer disease pathogenesis
D'Adamio, L.
8/1/21 → 4/30/22
Project: Research project

7163 Citations
46 h-Index
109 Article
3 Comment/debate
3 Review article

A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission
Yin, T., Yao, W., Norris, K. A. & D'Adamio, L., Sep 1 2021, In: Journal of Biological Chemistry. 297, 3, 101089.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Danish and British dementia ITM2b/BRI2 mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission
Yin, T., Yao, W., Lemenze, A. D. & D'Adamio, L., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100054.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Scopus citations
TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H rats
Ren, S., Breuillaud, L., Yao, W., Yin, T., Norris, K. A., Zehntner, S. P. & D'Adamio, L., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100089.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Knock-in rats with homozygous PSEN1^L435F Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43
Tambini, M. D. & D'Adamio, L., May 22 2020, In: Journal of Biological Chemistry. 295, 21, p. 7442-7451 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
11 Scopus citations
Microglia TREM2^R47H alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels
Ren, S., Yao, W., Tambini, M. D., Yin, T., Norris, K. A. & D’adamio, L., Jun 2020, In: eLife. 9, p. 1-18 18 p., e57513.
Research output: Contribution to journal › Article › peer-review

Open Access
13 Scopus citations

Luciano D'Adamio

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Trem2-mediated microglia-neuronal axis in Alzheimer disease pathogenesis

A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission

Danish and British dementia ITM2b/BRI2 mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission

TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H rats

Knock-in rats with homozygous PSEN1^L435F Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43

Microglia TREM2^R47H alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

Luciano D'Adamio

Fingerprint

Network

Projects

Trem2-mediated microglia-neuronal axis in Alzheimer disease pathogenesis

Research output

A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission

Danish and British dementia ITM2b/BRI2 mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission

TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H rats

Knock-in rats with homozygous PSEN1L435F Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43

Microglia TREM2R47H alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

Knock-in rats with homozygous PSEN1^L435F Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43

Microglia TREM2^R47H alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels