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Dive into the research topics where Mark Siracusa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Car4 regulates M2 macrophage responses and host protection to helminths
Siracusa, M. (PI)
National Institute of Allergy and Infectious Diseases
6/7/24 → 4/30/26
Project: Research project
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The role of pathogen-experienced macrophage subsets in mediating lung immunity and heterologous protection
Rivera-Medina, A. (PI), Siracusa, M. (CoPI) & Gause, W. (CoPI)
National Institute of Allergy and Infectious Diseases
7/14/23 → 6/30/26
Project: Research project
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New innovations: advancing mast cell biology
Siracusa, M. M. C. (CoPI) & Siracusa, M. (PI)
National Institute of Allergy and Infectious Diseases
5/23/22 → 4/30/24
Project: Research project
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Neuropeptide-mediated regulation of antihelminth immunity
Artis, D. (CoPI), Siracusa, M. C. (CoPI) & Siracusa, M. (PI)
National Institute of Allergy and Infectious Diseases
9/17/20 → 8/31/25
Project: Research project
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Protective and pathologic functions of macrophages induced by helminths
Siracusa, M. (PI) & Gause, W. (CoPI)
National Institute of Allergy and Infectious Diseases
12/20/17 → 11/30/22
Project: Research project
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Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production
Peng, J., Sy, C. B., Zhao, S., Sawhney, A., Espinosa, V., Schroeter, M. N., Ponessa, J. J., Chavan, K., Lemenze, A., Rivera-Medina, A., Rohacs, T. & Siracusa, M. C., 2025, In: Frontiers in immunology. 16, 1694105.Research output: Contribution to journal › Article › peer-review
Open Access -
IL-4 and TGF-β regulate inflammatory cytokines and cellular infiltration in the lung and systemic IL-6 in mouse-adapted SARS-CoV-2 infection
Sima, S. T., Puebla-Clark, L., Gonzalez-Orozco, M., Endrino, M. J., Shelite, T. R., Tseng, H. C., Martinez-Martinez, Y. B., Huante, M. B., Federman, H. G., Gbedande, K., Menachery, V. D., Siracusa, M. C., Endsley, M. A., Dann, S. M., Endsley, J. J., Rajsbaum, R. & Stephens, R., Sep 2025, In: ImmunoHorizons. 9, 9, vlaf032.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Communication is key: Innate immune cells regulate host protection to helminths
Peng, J., Federman, H. G., Hernandez, C. & Siracusa, M. C., Sep 26 2022, In: Frontiers in immunology. 13, 995432.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors
Espinosa, V., Dutta, O., Heung, L. J., Wang, K., Chang, Y. J., Soteropoulos, P., Hohl, T. M., Siracusa, M. C. & Rivera, A., Nov 15 2022, In: Journal of Immunology. 209, 10, p. 1827-1831 5 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion
Chen, F., El-Naccache, D. W., Ponessa, J. J., Lemenze, A., Espinosa, V., Wu, W., Lothstein, K., Jin, L., Antao, O., Weinstein, J. S., Damani-Yokota, P., Khanna, K., Murray, P. J., Rivera, A., Siracusa, M. C. & Gause, W. C., Jan 11 2022, In: Cell Reports. 38, 2, 110215.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations