Research output per year
Research output per year
- 1 - 50 out of 61 results
Search results
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2023
Cadmium reduces growth of male fetuses by impairing development of the placental vasculature and reducing expression of nutrient transporters
Kozlosky, D., Lu, A., Doherty, C., Buckley, B., Goedken, M., Miller, R. K., Barrett, E. S. & Aleksunes, L. M., Sep 15 2023, In: Toxicology and Applied Pharmacology. 475, 116636.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Ingested Polystyrene Nanospheres Translocate to Placenta and Fetal Tissues in Pregnant Rats: Potential Health Implications
Cary, C. M., DeLoid, G. M., Yang, Z., Bitounis, D., Polunas, M., Goedken, M. J., Buckley, B., Cheatham, B., Stapleton, P. A. & Demokritou, P., Feb 2023, In: Nanomaterials. 13, 4, 720.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Isothiocyanate-rich moringa seed extract reduces skin inflammation in mouse ear edema model
Wolff, K., Robinson, K., Suh, N., Michniak-Kohn, B., Goedken, M., Polunas, M. & Raskin, I., Nov 2023, In: Phytomedicine Plus. 3, 4, 100479.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Metabolic rewiring and epigenetic reprogramming in leptin receptor-deficient db/db diabetic nephropathy mice
Sarwar, M. S., Cheng, D., Peter, R. M., Shannar, A., Chou, P., Wang, L., Wu, R., Sargsyan, D., Goedken, M., Wang, Y., Su, X., Hart, R. P. & Kong, A.-N., Aug 15 2023, In: European Journal of Pharmacology. 953, p. 175866Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats
Cary, C. M., Seymore, T. N., Singh, D., Vayas, K. N., Goedken, M., Adams, S., Polunas, M., Sunil, V. R., Laskin, D. L., Demokritou, P. & Stapleton, P. A., Dec 2023, In: Particle and Fibre Toxicology. 20, 1, 16.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2022
Farnesoid X receptor regulates lung macrophage activation and injury following nitrogen mustard exposure
Murray, A., Banota, T., Guo, G. L., Smith, L. C., Meshanni, J. A., Lee, J., Kong, B., Abramova, E. V., Goedken, M., Gow, A. J., Laskin, J. D. & Laskin, D. L., Nov 1 2022, In: Toxicology and Applied Pharmacology. 454, 116208.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2021
Bile acid homeostasis in female mice deficient in Cyp7a1 and Cyp27a1
Rizzolo, D., Kong, B., Taylor, R. E., Brinker, A., Goedken, M., Buckley, B. & Guo, G. L., Dec 2021, In: Acta Pharmaceutica Sinica B. 11, 12, p. 3847-3856 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Development of coronary dysfunction in adult progeny after maternal engineered nanomaterial inhalation during gestation
Fournier, S. B., Lam, V., Goedken, M. J., Fabris, L. & Stapleton, P. A., Dec 2021, In: Scientific reports. 11, 1, 19374.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Pregnane X receptor exacerbates nonalcoholic fatty liver disease accompanied by obesity- and inflammation-prone gut microbiome signature
Kim, S., Choi, S., Dutta, M., Asubonteng, J. O., Polunas, M., Goedken, M., Gonzalez, F. J., Cui, J. Y. & Gyamfi, M. A., Nov 2021, In: Biochemical Pharmacology. 193, 114698.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
The role of maternal high fat diet on mouse pup metabolic endpoints following perinatal PFAS and PFAS mixture exposure
Marques, E. S., Agudelo, J., Kaye, E. M., Modaresi, S. M. S., Pfohl, M., Bečanová, J., Wei, W., Polunas, M., Goedken, M. & Slitt, A. L., Oct 2021, In: Toxicology. 462, 152921.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2020
Acute feeding suppression and toxicity of raspberry ketone [4-(4-hydroxyphenyl)-2-butanone] in mice
Hao, L., Kshatriya, D., Li, X., Badrinath, A., Szmacinski, Z., Goedken, M., Polunas, M. & Bello, N. T., Sep 2020, In: Food and Chemical Toxicology. 143, 111512.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Direct and Indirect Effects of Fibroblast Growth Factor (FGF) 15 and FGF19 on Liver Fibrosis Development
Schumacher, J. D., Kong, B., Wu, J., Rizzolo, D., Armstrong, L. E., Chow, M. D., Goedken, M., Lee, Y.-H. & Guo, G. L., Feb 1 2020, In: Hepatology. 71, 2, p. 670-685 16 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard
Sunil, V. R., Vayas, K. N., Abramova, E. V., Rancourt, R., Cervelli, J. A., Malaviya, R., Goedken, M., Venosa, A., Gow, A. J., Laskin, J. D. & Laskin, D. L., Jan 15 2020, In: Toxicology and Applied Pharmacology. 387, 114798.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy
Fournier, S. B., D’Errico, J. N., Adler, D. S., Kollontzi, S., Goedken, M. J., Fabris, L., Yurkow, E. J. & Stapleton, P. A., Dec 1 2020, In: Particle and Fibre Toxicology. 17, 1, 55.Research output: Contribution to journal › Article › peer-review
Open Access224 Scopus citations -
2019
Bile Acid Homeostasis in a Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase Double Knockout Mouse Model
Rizzolo, D., Buckley, K., Kong, B., Zhan, L., Shen, J., Stofan, M., Brinker, A., Goedken, M., Buckley, B. & Guo, G. L., Jul 2019, In: Hepatology. 70, 1, p. 389-402 14 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis
Malekshah, O. M., Sarkar, S., Nomani, A., Patel, N., Javidian, P., Goedken, M., Polunas, M., Louro, P. & Hatefi, A., Oct 2019, In: Journal of Controlled Release. 311-312, p. 273-287 15 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Coencapsulation of ISCs and MSCs Enhances Viability and Function of both Cell Types for Improved Wound Healing
Aijaz, A., Teryek, M., Goedken, M., Polunas, M. & Olabisi, R., Oct 1 2019, In: Cellular and Molecular Bioengineering. 12, 5, p. 481-493 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Identification and quantification of gold engineered nanomaterials and impaired fluid transfer across the rat placenta via ex vivo perfusion
D'Errico, J. N., Doherty, C., Fournier, S. B., Renkel, N., Kallontzi, S., Goedken, M., Fabris, L., Buckley, B. & Stapleton, P. A., Sep 2019, In: Biomedicine and Pharmacotherapy. 117, 109148.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity
Donepudi, A. C., Goedken, M. J., Schuetz, J. D. & E Manautou, J., 2019, In: Toxicology Reports. 6, p. 841-849 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity
Clarke, J. D., Dzierlenga, A., Arman, T., Toth, E., Li, H., Lynch, K. D., Tian, D. D., Goedken, M., Paine, M. F. & Cherrington, N., Apr 15 2019, In: Toxicon. 162, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Sub-chronic microcystin-LR liver toxicity in preexisting diet-induced nonalcoholic steatohepatitis in rats
Arman, T., Lynch, K. D., Montonye, M. L., Goedken, M. & Clarke, J. D., Jul 9 2019, In: Toxins. 11, 7, toxins11070398.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2018
Gene-by-environment interaction of Bcrp-/- and methionine-and choline-deficient diet-induced nonalcoholic steatohepatitis alters SN-38 disposition
Toth, E. L., Li, H., Dzierlenga, A. L., Clarke, J. D., Vildhede, A., Goedken, M. & Cherrington, N. J., Nov 2018, In: Drug Metabolism and Disposition. 46, 11, p. 1478-1486 9 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Novel bone morphogenetic protein receptor inhibitor JL5 suppresses tumor cell survival signaling and induces regression of human lung cancer
Newman, J. H., Augeri, D. J., Nemoyer, R., Malhotra, J., Langenfeld, E., Chesson, C. B., Dobias, N. S., Lee, M. J., Tarabichi, S., Jhawar, S. R., Bommareddy, P. K., Marshall, S., Sadimin, E. T., Kerrigan, J. E., Goedken, M., Minerowicz, C., Jabbour, S. K., Li, S., Carayannopolous, M. O. & Zloza, A. & 1 others, , Jul 5 2018, In: Oncogene. 37, 27, p. 3672-3685 14 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Protective Role of Surfactant Protein-D Against Lung Injury and Oxidative Stress Induced by Nitrogen Mustard
Sunil, V. R., Vayas, K. N., Cervelli, J. A., Ebramova, E. V., Gow, A. J., Goedken, M., Malaviya, R., Laskin, J. D. & Laskin, D. L., Nov 1 2018, In: Toxicological sciences : an official journal of the Society of Toxicology. 166, 1, p. 108-122 15 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2017
In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice
Li, H., Clarke, J. D., Dzierlenga, A. L., Bear, J., Goedken, M. J. & Cherrington, N. J., Feb 1 2017, In: Journal of Biochemical and Molecular Toxicology. 31, 2, e21840.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis
Schumacher, J. D., Kong, B., Pan, Y., Zhan, L., Sun, R., Aa, J., Rizzolo, D., Richardson, J. R., Chen, A., Goedken, M., Aleksunes, L. M., Laskin, D. L. & Guo, G. L., Sep 1 2017, In: Toxicology and Applied Pharmacology. 330, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
2016
Effect of nonalcoholic steatohepatitis on renal filtration and secretion of adefovir
Laho, T., Clarke, J. D., Dzierlenga, A. L., Li, H., Klein, D. M., Goedken, M., Micuda, S. & Cherrington, N. J., Sep 1 2016, In: Biochemical Pharmacology. 115, p. 144-151 8 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Enhanced hepatotoxicity by acetaminophen in Vanin-knockout mice is associated with deficient proliferative and immune responses
Ferreira, D. W., Goedken, M. J., Rommelaere, S., Chasson, L., Galland, F., Naquet, P. & Manautou, J. E., Apr 1 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 4, p. 662-669 8 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2015
Interactions between nuclear receptor SHP and FOXA1 maintain oscillatory homocysteine homeostasis in mice
Tsuchiya, H., Da Costa, K. A., Lee, S., Renga, B., Jaeschke, H., Yang, Z., Orena, S. J., Goedken, M., Zhang, Y., Kong, B., Lebofsky, M., Rudraiah, S., Smalling, R., Guo, G., Fiorucci, S., Zeisel, S. H. & Wang, L., May 1 2015, In: Gastroenterology. 148, 5, p. 1012-1023.e14Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Mechanism of altered metformin distribution in nonalcoholic steatohepatitis
Clarke, J. D., Dzierlenga, A. L., Nelson, N. R., Li, H., Werts, S., Goedken, M. J. & Cherrington, N. J., Sep 2015, In: Diabetes. 64, 9, p. 3305-3313 9 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Multidrug resistance-associated protein 3 plays an important role in protection against acute toxicity of diclofenac
Scialis, R. J., Csanaky, I. L., Goedken, M. J. & Manautou, J. E., Jul 1 2015, In: Drug Metabolism and Disposition. 43, 7, p. 944-950 7 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis
Canet, M. J., Hardwick, R. N., Lake, A. D., Dzierlenga, A. L., Clarke, J. D., Goedken, M. J. & Cherrington, N. J., Jan 1 2015, In: Drug Metabolism and Disposition. 43, 2, p. 266-272 7 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice
Ghanem, C. I., Rudraiah, S., Bataille, A. M., Vigo, M. B., Goedken, M. J. & Manautou, J. E., Apr 1 2015, In: Biochemical Pharmacology. 94, 3, p. 203-211 9 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2014
Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis
Hardwick, R. N., Clarke, J. D., Lake, A. D., Canet, M. J., Anumol, T., Street, S. M., Merrell, M. D., Goedken, M. J., Snyder, S. A. & Cherrington, N. J., Nov 1 2014, In: Toxicological Sciences. 142, 1, p. 45-55 11 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Is nuclear factor erythroid 2-Related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in Mice?
Rohrer, P. R., Rudraiah, S., Goedken, M. J. & Manautou, J. E., Oct 1 2014, In: Drug Metabolism and Disposition. 42, 10, p. 1663-1674 12 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells
Wen, X., Gibson, C. J., Yang, I., Buckley, B., Goedken, M., Richardson, J. R. & Aleksunes, L. M., Oct 1 2014, In: Toxicological Sciences. 141, 2, p. 475-483 9 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Synergistic interaction between genetics and disease on pravastatin disposition
Clarke, J. D., Hardwick, R. N., Lake, A. D., Lickteig, A. J., Goedken, M. J., Klaassen, C. D. & Cherrington, N. J., Jul 2014, In: Journal of Hepatology. 61, 1, p. 139-147 9 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat
Kyriakides, M., Hardwick, R. N., Jin, Z., Goedken, M. J., Holmes, E., Cherrington, N. J. & Coen, M., Nov 1 2014, In: Toxicological Sciences. 142, 1, p. 105-116 12 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes
Rudraiah, S., Rohrer, P. R., Gurevich, I., Goedken, M. J., Rasmussen, T., Hines, R. N. & Manautou, J. E., Sep 12 2014, In: Toxicological Sciences. 141, 1, p. 263-277 15 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-Null mice
Wen, X., Buckley, B., McCandlish, E., Goedken, M., Syed, S., Pelis, R., Manautou, J. E. & Aleksunes, L. M., May 2014, In: American Journal of Pathology. 184, 5, p. 1299-1308 10 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
2013
Inhibin B Response to Testicular Toxicants Hexachlorophene, Ethane Dimethane Sulfonate, Di-(n-butyl)-phthalate, Nitrofurazone, DL-Ethionine, 17-alpha Ethinylestradiol, 2,5-Hexanedione, or Carbendazim Following Short-Term Dosing in Male Rats
Erdos, Z., Pearson, K., Goedken, M., Menzel, K., Sistare, F. D., Glaab, W. E. & Saldutti, L. P., Feb 2013, In: Birth Defects Research Part B - Developmental and Reproductive Toxicology. 98, 1, p. 41-53 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Pregnancy represses induction of efflux transporters in livers of type i diabetic mice
Aleksunes, L. M., Xu, J., Lin, E., Wen, X., Goedken, M. & Slitt, A. L., Sep 2013, In: Pharmaceutical research. 30, 9, p. 2209-2220 12 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2010
Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice
Aleksunes, L. M., Reisman, S. A., Yeager, R. L., Goedken, M. J. & Klaassen, C. D., Apr 2010, In: Journal of Pharmacology and Experimental Therapeutics. 333, 1, p. 140-151 12 p.Research output: Contribution to journal › Article › peer-review
Open Access100 Scopus citations -
Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity
Aleksunes, L. M., Goedken, M. J., Rockwell, C. E., Thomale, J., Manautou, J. E. & Klaassen, C. D., Oct 2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 1, p. 2-12 11 p.Research output: Contribution to journal › Article › peer-review
Open Access151 Scopus citations -
2009
Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-Null mice
Cui, Y. J., Aleksunes, L. M., Tanaka, Y., Goedken, M. J. & Klaassen, C. D., 2009, In: Toxicological Sciences. 110, 1, p. 47-60 14 p.Research output: Contribution to journal › Article › peer-review
Open Access108 Scopus citations -
Effect of allyl alcohol on hepatic transporter expression: Zonal patterns of expression and role of Kupffer cell function
Campion, S. N., Tatis-Rios, C., Augustine, L. M., Goedken, M. J., van Rooijen, N., Cherrington, N. J. & Manautou, J. E., Apr 1 2009, In: Toxicology and Applied Pharmacology. 236, 1, p. 49-58 10 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2008
Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes
Aleksunes, L. M., Campion, S. N., Goedken, M. J. & Manautou, J. E., Aug 2008, In: Toxicological Sciences. 104, 2, p. 261-273 13 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity
Tanaka, Y., Aleksunes, L. M., Goedken, M. J., Chen, C., Reisman, S. A., Manautou, J. E. & Klaassen, C. D., Sep 15 2008, In: Toxicology and Applied Pharmacology. 231, 3, p. 364-373 10 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Development of new methods to assess invertebrate immunology and immunotoxicology in aquaculture: Oysters and lobsters as examples
De Guise, S., Goedken, M., Morsey, B., Maratea, J., Sidor, I. & Perkins, C., Sep 2008, In: International Journal of Environment and Pollution. 33, 4, p. 365-380 16 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function
Campion, S. N., Johnson, R., Aleksunes, L. M., Goedken, M. J., Van Rooijen, N., Scheffer, G. L., Cherrington, N. J. & Manautou, J. E., Aug 2008, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 2, p. G294-G304Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations