Projects per year
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 17 Finished
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Targeting retroviral and virus-like particles for gene and protein delivery
Roth, M. (CoPI)
National Institute of General Medical Sciences
9/30/17 → 12/31/24
Project: Research project
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Interactions of MuLV IN with host proteins and DNA
Roth, M. (PI)
National Institute of General Medical Sciences
5/1/16 → 4/30/19
Project: Research project
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Targeted delivery of Cas9/gRNA directed to HIV latent/persistent cells
Roth, M. (PI)
National Institute of Allergy and Infectious Diseases
8/1/15 → 7/31/16
Project: Research project
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MuLV p12 function in tethering & integration
Roth, M. (PI)
National Institute of General Medical Sciences
1/1/14 → 12/31/18
Project: Research project
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Retroviral Integration & HDAC inhibitors
Roth, M. (PI)
National Institute of General Medical Sciences
8/1/09 → 7/31/15
Project: Research project
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A Computational Pipeline for Accurate Prioritization of Protein-Protein Binding Candidates in High-Throughput Protein Libraries
Mondal, A., Singh, B., Felkner, R. H., De Falco, A., Swapna, G. V. T., Montelione, G. T., Roth, M. J. & Perez, A., Jun 10 2024, In: Angewandte Chemie - International Edition. 63, 24, e202405767.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Structure Determination of Challenging Protein-Peptide Complexes Combining NMR Chemical Shift Data and Molecular Dynamics Simulations
Mondal, A., Swapna, G., Lopez, M. M., Klang, L., Hao, J., Ma, L. C., Roth, M. J., Montelione, G. T. & Perez, A., Apr 10 2023, In: Journal of Chemical Information and Modeling. 63, 7, p. 2058-2072 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins
Aiyer, S., Swapna, G. V. T., Ma, L. C., Liu, G., Hao, J., Chalmers, G., Jacobs, B. C., Montelione, G. T. & Roth, M. J., Aug 5 2021, In: Structure. 29, 8, p. 886-898.e6Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model
Loyola, L., Achuthan, V., Gilroy, K., Borland, G., Kilbey, A., MacKay, N., Bell, M., Hay, J., Aiyer, S., Fingerman, D., Villanueva, R. A., Cameron, E., Kozak, C. A., Engelman, A. N., Neil, J. & Roth, M. J., 2019, In: PLoS pathogens. 15, 12, e1008154.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition
Guan, R., Aiyer, S., Cote, M. L., Xiao, R., Jiang, M., Acton, T. B., Roth, M. J. & Montelione, G. T., Apr 1 2017, In: Proteins: Structure, Function and Bioinformatics. 85, 4, p. 647-656 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations