Projects per year
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Collaborations and top research areas from the last five years
Projects
- 13 Finished
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Repurposing Mycobacterium tuberculosis tRNase toxins for cancer chemotherapy
Woychik, N. (CoPI)
12/1/21 → 11/30/23
Project: Research project
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Genome exploration through toxin-mediated ribosome stalling
Woychik, N. (CoPI)
National Institute of Allergy and Infectious Diseases
5/7/20 → 4/30/24
Project: Research project
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Proteome reprogramming by tRNA-cleaving toxins
Woychik, N. (PI)
National Institute of Allergy and Infectious Diseases
2/21/20 → 1/31/22
Project: Research project
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Transcriptome and proteome remodeling by Mycobacterium tuberculosis MazF toxins
Woychik, N. (CoPI)
National Institute of Allergy and Infectious Diseases
12/1/19 → 11/30/23
Project: Research project
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Molecular triggers of persistent Mycobacterium abscessus infections
Woychik, N. (PI)
National Institute of Allergy and Infectious Diseases
7/2/18 → 6/30/21
Project: Research project
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Phosphorylation of VapB antitoxins affects intermolecular interactions to regulate VapC toxin activity in Mycobacterium tuberculosis
Malakar, B., Barth, V. C., Puffal, J., Woychik, N. A. & Husson, R. N., Oct 2024, In: Journal of bacteriology. 206, 10, e00233-24.Research output: Contribution to journal › Article › peer-review
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Mycobacterium abscessus VapC5 toxin potentiates evasion of antibiotic killing by ribosome overproduction and activation of multiple resistance pathways
Troian, E. A., Maldonado, H. M., Chauhan, U., Barth, V. C. & Woychik, N. A., Dec 2023, In: Nature communications. 14, 1, 3705.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
tRNAfMet Inactivating Mycobacterium tuberculosis VapBC Toxin- Antitoxin Systems as Therapeutic Targets
Chauhan, U., Barth, V. C. & Woychik, N. A., May 2022, In: Antimicrobial agents and chemotherapy. 66, 5Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Mycobacterium tuberculosis VapC4 toxin engages small ORFs to initiate an integrated oxidative and copper stress response
Barth, V. C., Chauhan, U., Zeng, J., Su, X., Zheng, H., Husson, R. N. & Woychik, N. A., Aug 10 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 32, e2022136118.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
The Sole Mycobacterium smegmatis MazF Toxin Targets tRNALys to Impart Highly Selective, Codon-Dependent Proteome Reprogramming
Barth, V. C. & Woychik, N. A., Feb 14 2020, In: Frontiers in Genetics. 10, 1356.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations