Projects per year
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Projects
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Evaluation of the lysosomal protease tripeptidyl peptidase 1 as a potential therapeutic for Alzheimer Disease
8/15/19 → 4/30/21
Project: Research project
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Establishment of a UMDNJ NeuroProteomics Core Facility
Lobel, P., Lobel, P., Li, H., Li, H., Li, H. & Lobel, P.
National Institute of Neurological Disorders and Stroke
9/15/04 → 6/30/21
Project: Research project
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NOVEL LYSOSOMAL ENZYME DEFICIENT IN BATTEN DISEASE
Lobel, P., LOBEL, P., LOBEL, P., LOBEL, P. & LOBEL, P.
National Institute of Neurological Disorders and Stroke
4/1/98 → 5/31/21
Project: Research project
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A Mass Spectrometry System for Quantitative Proteomics
Lobel, P. & LOBEL, P.
7/1/14 → 6/30/15
Project: Research project
Research output
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Comparative Analysis of Quantitative Mass Spectrometric Methods for Subcellular Proteomics
Tannous, A., Boonen, M., Zheng, H., Zhao, C., Germain, C. J., Moore, D. F., Sleat, D. E., Jadot, M. & Lobel, P., 2020, (Accepted/In press) In: ACS Applied Materials and Interfaces.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Lysosomal protein thermal stability does not correlate with cellular half-life: Global observations and a case study of tripeptidyl-peptidase 1
Collier, A. M., Nemtsova, Y., Kuber, N., Banach-Petrosky, W., Modak, A., Sleat, D. E., Nanda, V. & Lobel, P., 2020, In: Biochemical Journal. 477, 3, p. 727-745 19 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Analysis of brain and cerebrospinal fluid from mouse models of the three major forms of neuronal ceroid lipofuscinosis reveals changes in the lysosomal proteome
Sleat, D. E., Wiseman, J. A., El-Banna, M., Zheng, H., Zhao, C., Soherwardy, A., Moore, D. F. & Lobel, P., 2019, In: Molecular and Cellular Proteomics. 18, 11, p. 2244-2261 18 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis
Nemtsova, Y., Wiseman, J. A., El-Banna, M., Lobel, P. & Sleat, D. E., Feb 2018, In: PloS one. 13, 2, e0192286.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain
Solé-Domènech, S., Rojas, A. V., Maisuradze, G. G., Scheraga, H. A., Lobel, P. & Maxfield, F. R., Feb 13 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. 1493-1498 6 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations