Projects per year
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
Neuronal Ceroid-Lipofuscinoses
Medicine & Life Sciences
Ceroid
Chemical Compounds
IGF Type 2 Receptor
Medicine & Life Sciences
Lysosomes
Medicine & Life Sciences
Enzymes
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Glycoproteins
Medicine & Life Sciences
Lysosomal Storage Diseases
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1998 2016
- 4 Finished
Rutgers Mass Spectrometry Core For Integrative Neuroscience Research
National Institutes of Health (NIH)
7/1/15 → 6/30/16
Project: Research project
Mass spectrometers
Mass spectrometry
Biomarkers
Design of experiments
Proteins
A Mass Spectrometry System For Quantitative Proteomics
National Institutes of Health (NIH)
7/1/14 → 6/30/15
Project: Research project
Mass spectrometry
Neurodegenerative diseases
Liquid chromatography
Mass spectrometers
Pathogens
Lysosomal Enzymes And Associated Human Genetic Diseases
National Institutes of Health (NIH)
7/1/13 → 3/31/14
Project: Research project
Inborn Genetic Diseases
Medical Genetics
Enzymes
Genes
Proteome
Novel Lysosomal Enzyme Deficient In Batten Disease
National Institutes of Health (NIH)
4/1/98 → 11/30/16
Project: Research project
Neuronal Ceroid-Lipofuscinoses
Enzymes
Therapeutics
Enzyme Replacement Therapy
Disease Progression
Research Output 1983 2018
1
Citation
(Scopus)
Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis
Nemtsova, Y., Wiseman, J. A., El-Banna, M., Lobel, P. & Sleat, D. E., Feb 1 2018, In : PloS one. 13, 2, e0192286.Research output: Contribution to journal › Article
Ceroid
Neuronal Ceroid-Lipofuscinoses
peptidases
animal models
gene expression
4
Citations
(Scopus)
Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain
Solé-Domènech, S., Rojas, A. V., Maisuradze, G. G., Scheraga, H. A., Lobel, P. & Maxfield, F. R., Feb 13 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. 1493-1498 6 p.Research output: Contribution to journal › Article
Enzymes
Endopeptidases
Cathepsin B
Peptides
Microglia
3
Citations
(Scopus)
A Basic ApoE-Based Peptide Mediator to Deliver Proteins across the Blood-Brain Barrier: Long-Term Efficacy, Toxicity, and Mechanism
Meng, Y., Wiseman, J. A., Nemtsova, Y., Moore, D., Guevarra, J., Reuhl, K., Banks, W. A., Daneman, R., Sleat, D. E. & Lobel, P., Jul 5 2017, In : Molecular Therapy. 25, 7, p. 1531-1543 13 p.Research output: Contribution to journal › Article
Apolipoproteins E
Blood-Brain Barrier
Neuronal Ceroid-Lipofuscinoses
Peptides
Brain
16
Citations
(Scopus)
Accounting for protein subcellular localization: A compartmental map of the rat liver proteome
Jadot, M., Boonen, M., Thirion, J., Wang, N., Xing, J., Zhao, C., Tannous, A., Qian, M., Zheng, H., Everett, J. K., Moore, D., Sleat, D. E. & Lobel, P., Feb 1 2017, In : Molecular and Cellular Proteomics. 16, 2, p. 194-212 19 p.Research output: Contribution to journal › Article
Proteome
Liver
Rats
Organelles
Proteins
5
Citations
(Scopus)
Chronic Enzyme Replacement to the Brain of a Late Infantile Neuronal Ceroid Lipofuscinosis Mouse Has Differential Effects on Phenotypes of Disease
Wiseman, J. A., Meng, Y., Nemtsova, Y., Matteson, P. G., Millonig, J., Moore, D., Sleat, D. E. & Lobel, P., Mar 17 2017, In : Molecular Therapy - Methods and Clinical Development. 4, p. 204-212 9 p.Research output: Contribution to journal › Article
Neuronal Ceroid-Lipofuscinoses
Phenotype
Brain
Enzymes
Enzyme Replacement Therapy