If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research interests

We use human induced pluripotent stem cells (iPSC) to model neurons with specific genetic variants to study Alzheimer's disease, Ataxia-telangiectasia, and addiction disorders.

Education/Academic qualification

Cellular and Molecular Biology, Ph.D., University of Michigan

Sep 1 1977Aug 20 1981

Biology, B.S., University of Connecticut

Sep 1 1973May 23 1977

Molecular Biology, Postdoctoral Training, Rockefeller University

Sep 1 1982Aug 31 1985

Molecular Biology, Postdoctoral Training, University of Michigan

Sep 1 1981Aug 31 1982

External positions

Member, Scientific Advisory Board, Neucyte, Inc.

Sep 1 2017 → …

Member, State of Connecticut Regenerative Medicine Research Fund

Jun 1 2009 → …

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 13 Similar Profiles
Messenger RNA Medicine & Life Sciences
Spinal Cord Injuries Medicine & Life Sciences
Substance P Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Neurons Medicine & Life Sciences
Interleukin-1 Medicine & Life Sciences
Sympathetic Ganglia Medicine & Life Sciences
Genes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1982 2018

Compartmentalized devices as tools for investigation of human brain network dynamics

Fantuzzo, J. A., Hart, R. P., Zahn, J. D. & Pang, Z. P., Aug 17 2018, In : Developmental Dynamics.

Research output: Contribution to journalReview article

Organoids
Induced Pluripotent Stem Cells
Equipment and Supplies
Brain
Preclinical Drug Evaluations

DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice

Guo, Y., Wu, R., Gaspar, J. M., Sargsyan, D., Su, Z-Y., Zhang, C., Gao, L., Cheng, D., Li, W., Wang, C., Yin, R., Fang, M., Verzi, M. P., Hart, R. P. & Kong, A-N., May 3 2018, In : Carcinogenesis. 39, 5, p. 669-680 12 p.

Research output: Contribution to journalArticle

Curcumin
Colitis
Transcriptome
Colonic Neoplasms
Azoxymethane

Epigenetic alterations in TRAMP mice: Epigenome DNA methylation profiling using MeDIP-seq

Li, W., Huang, Y., Sargsyan, D., Khor, T. O., Guo, Y., Shu, L., Yang, A. Y., Zhang, C., Paredes-Gonzalez, X., Verzi, M., Hart, R. & Kong, A-N., Jan 12 2018, In : Cell and Bioscience. 8, 1, 3.

Research output: Contribution to journalArticle

Methylation
DNA Fingerprinting
DNA Methylation
Immunoprecipitation
Epigenomics
1 Citations

Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?

Prytkova, I., Goate, A., Hart, R. P. & Slesinger, P. A., Jun 13 2018, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalReview article

Induced Pluripotent Stem Cells
Stem cells
Genes
Alcohols
Association reactions

Histone acetylation maps in aged mice developmentally exposed to lead: Epigenetic drift and Alzheimer-related genes

Eid, A., Bihaqi, S. W., Hemme, C., Gaspar, J. M., Hart, R. & Zawia, N. H., May 1 2018, In : Epigenomics. 10, 5, p. 573-583 11 p.

Research output: Contribution to journalArticle

Acetylation
Epigenomics
Histones
Genes
Alzheimer Disease