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Personal profile

Research interests

We use human induced pluripotent stem cells (iPSC) to model neurons with specific genetic variants to study Alzheimer's disease, Ataxia-telangiectasia, and addiction disorders.

Education/Academic qualification

Cellular and Molecular Biology, Ph.D., University of Michigan

Sep 1 1977Aug 20 1981

Biology, B.S., University of Connecticut

Sep 1 1973May 23 1977

Molecular Biology, Postdoctoral Training, Rockefeller University

Sep 1 1982Aug 31 1985

Molecular Biology, Postdoctoral Training, University of Michigan

Sep 1 1981Aug 31 1982

External positions

Member, Scientific Advisory Board, Neucyte, Inc.

Sep 1 2017 → …

Member, State of Connecticut Regenerative Medicine Research Fund

Jun 1 2009 → …

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1982 2018

Compartmentalized devices as tools for investigation of human brain network dynamics

Fantuzzo, J. A., Hart, R. P., Zahn, J. D. & Pang, Z. P., Aug 17 2018, In : Developmental Dynamics.

Research output: Contribution to journalReview article

Induced Pluripotent Stem Cells
Equipment and Supplies
Preclinical Drug Evaluations

DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice

Guo, Y., Wu, R., Gaspar, J. M., Sargsyan, D., Su, Z-Y., Zhang, C., Gao, L., Cheng, D., Li, W., Wang, C., Yin, R., Fang, M., Verzi, M. P., Hart, R. P. & Kong, A-N., May 3 2018, In : Carcinogenesis. 39, 5, p. 669-680 12 p.

Research output: Contribution to journalArticle

Colonic Neoplasms

Epigenetic alterations in TRAMP mice: Epigenome DNA methylation profiling using MeDIP-seq

Li, W., Huang, Y., Sargsyan, D., Khor, T. O., Guo, Y., Shu, L., Yang, A. Y., Zhang, C., Paredes-Gonzalez, X., Verzi, M., Hart, R. & Kong, A-N., Jan 12 2018, In : Cell and Bioscience. 8, 1, 3.

Research output: Contribution to journalArticle

DNA Fingerprinting
DNA Methylation
1 Citations

Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?

Prytkova, I., Goate, A., Hart, R. P. & Slesinger, P. A., Jun 13 2018, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalReview article

Induced Pluripotent Stem Cells
Stem cells
Association reactions

Histone acetylation maps in aged mice developmentally exposed to lead: Epigenetic drift and Alzheimer-related genes

Eid, A., Bihaqi, S. W., Hemme, C., Gaspar, J. M., Hart, R. & Zawia, N. H., May 1 2018, In : Epigenomics. 10, 5, p. 573-583 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease