Projects per year
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Collaborations and top research areas from the last five years
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Mechanistic studies of nucleic acid enzymes involved in DNA replication, transcription, and innate immunity.
Patel, S. (CoPI) & Patel, S. S. S. (PI)
National Institute of General Medical Sciences
5/1/16 → 4/30/25
Project: Research project
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Structural and mechanistic studies of self and non-self recognition by RIG-I
Brewer, G. (PI), Marcotrigiano, J. (CoPI) & Patel, S. (CoPI)
National Institute of General Medical Sciences
9/15/14 → 5/31/19
Project: Research project
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Mechanism and Regulation of Transcription Initiation
Patel, S. (PI) & Patel, S. S. (CoPI)
National Institute of General Medical Sciences
9/1/07 → 6/30/16
Project: Research project
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Mechanistic Studies of Hexameric Helicases
Patel, S. (CoPI) & Patel, S. S. (PI)
National Institute of General Medical Sciences
1/1/97 → 7/31/17
Project: Research project
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Mechanism and Regulation of Transcription Initiation
Patel, S. (CoPI) & Patel, S. S. (PI)
National Institute of General Medical Sciences
1/1/95 → 5/31/07
Project: Research project
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Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA
Solotchi, M. & Patel, S. S., Jun 2024, In: Biochemical Society transactions. 52, 3, p. 1131-1148 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Sequence-specific dynamic DNA bending explains mitochondrial TFAM’s dual role in DNA packaging and transcription initiation
Huh, H., Shen, J., Ajjugal, Y., Ramachandran, A., Patel, S. S. & Lee, S. H., Dec 2024, In: Nature communications. 15, 1, 5446.Research output: Contribution to journal › Article › peer-review
Open Access -
Unraveling blunt-end RNA binding and ATPase-driven translocation activities of the RIG-I family helicase LGP2
Lee, K. Y., Craig, C. & Patel, S. S., Jan 11 2024, In: Nucleic acids research. 52, 1, p. 355-369 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Expression and Purification of Recombinant Human Mitochondrial RNA Polymerase (POLRMT) and the Initiation Factors TFAM and TFB2M
Hsieh, A. H., Reardon, S. D., Munozvilla-Cabellon, J. H., Shen, J., Patel, S. S. & Mishanina, T. V., Dec 1 2023, In: Bio-protocol. 13, 23, e4892.Research output: Contribution to journal › Article › peer-review
Open Access -
RIG-I recognizes metabolite-capped RNAs as signaling ligands
Schweibenz, B. D., Solotchi, M., Hanpude, P., Devarkar, S. C. & Patel, S. S., Aug 25 2023, In: Nucleic acids research. 51, 15, p. 8102-8114 13 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations