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Dive into the research topics where Sophie Astrof is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Identification of compensatory mechanisms to rescue aortic arch artery defects
Astrof, S. (CoPI)
National Heart, Lung, and Blood Institute
1/5/22 → 12/31/25
Project: Research project
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Role of integrin a5b1 in vascular patterning and the formation of the pharyngeal arch arteries
Astrof, S. (CoPI)
National Heart, Lung, and Blood Institute
7/1/10 → 8/31/25
Project: Research project
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Generation of novel Fn1-fluorescent fusion proteins in vivo for the investigation of cell_ECM dynamics in real time.
Astrof, S. (PI)
8/1/18 → 7/31/20
Project: Research project
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Mechanisms regulating the formation of the pharyngeal arch arteries
Astrof, S. (PI)
National Heart, Lung, and Blood Institute
8/15/17 → 5/31/21
Project: Research project
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Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development
Arriagada, C., Lin, E., Schonning, M. & Astrof, S., Jan 6 2025, In: Developmental Cell. 60, 1, p. 62-84.e7Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Buffering Mechanism in Aortic Arch Artery Formation and Congenital Heart Disease
Ramirez, A. J., Vyzas, C. A., Zhao, H., Eng, K., Degenhardt, K. & Astrof, S., May 10 2024, In: Circulation research. 134, 10, p. E112-E132Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
SMAD4: A critical regulator of cardiac neural crest cell fate and vascular smooth muscle development
Alexander, B. E., Zhao, H. & Astrof, S., Jan 2024, In: Developmental Dynamics. 253, 1, p. 119-143 25 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8
Astrof, S., Arriagada, C., Saijoh, Y., Francou, A., Kelly, R. G. & Moon, A., Jul 2023, In: Developmental Biology. 499, p. 10-21 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Initiation of fibronectin fibrillogenesis is an enzyme-dependent process
Melamed, S., Zaffryar-Eilot, S., Nadjar-Boger, E., Aviram, R., Zhao, H., Yaseen-Badarne, W., Kalev-Altman, R., Sela-Donenfeld, D., Lewinson, O., Astrof, S., Hasson, P. & Wolfenson, H., May 30 2023, In: Cell Reports. 42, 5, 112473.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations