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Stephen Burley, M.D., D.Phil.

 https://orcid.org/0000-0002-2487-9713
  • 29359 Citations
  • 82 h-Index
1976 …2020
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  • 7 Similar Profiles
Proteins Medicine & Life Sciences
X-Rays Medicine & Life Sciences
X Ray Crystallography Medicine & Life Sciences
Databases Medicine & Life Sciences
DNA Medicine & Life Sciences
TATA-Box Binding Protein Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Crystal structure Chemical Compounds

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Projects 1976 2019

PDB MANAGEMENT BY THE RESEARCH COLLABORATORY FOR STRUCTURAL BIOINFORMATICS

Burley, S.

National Science Foundation (National Science Foundation (NSF))

4/1/14 → 3/31/19

Project: Research project

data bank
management
biology
community
participation

Structure Based Drug Discovery

Burley, S.

National Institutes of Health

3/1/06 → 2/28/07

Project: Research project

Ligands
Toxicity
Membrane Proteins
Lead compounds
Proteins

NYSGXRC:A Large Scale Center for the PSI

Burley, S., Sali, A., Lima, C., Almo, S. C., Swaminathan, S. & Shapiro, L.

National Institutes of Health

7/1/05 → 6/30/11

Project: Research project

Proteins
Escherichia coli
Throughput
Wavelength
Crystallization

Structural Genomics

Burley, S.

National Institutes of Health

2/1/04 → 1/31/05

Project: Research project

X ray crystallography
Nuclear magnetic resonance spectroscopy
Proteins
Throughput
Technical presentations

CENTER FOR STRUCTURAL GENOMICS

Burley, S. & Bonanno, J.

National Institutes of Health

9/30/00 → 6/30/07

Project: Research project

Genomics
Proteins
Crystallography
Research
Crystallization

Research Output 1982 2020

RCSB Protein Data Bank: Enabling biomedical research and drug discovery

Goodsell, D. S., Zardecki, C., Di Costanzo, L., Duarte, J. M., Hudson, B. P., Persikova, I., Segura, J., Shao, C., Voigt, M., Westbrook, J. D., Young, J. Y. & Burley, S. K., Jan 1 2020, In : Protein Science. 29, 1, p. 52-65 14 p.

Research output: Contribution to journal › Review article

Drug Discovery
Biomedical Research
Databases
Proteins
Bioinformatics
2 Citations (Scopus)

Announcing mandatory submission of PDBx/mmCIF format files for crystallographic depositions to the protein data bank (PDB)

Adams, P. D., Afonine, P. V., Baskaran, K., Berman, H. M., Berrisford, J., Bricogne, G., Brown, D. G., Burley, S. K., Chen, M., Feng, Z., Flensburg, C., Gutmanas, A., Hoch, J. C., Ikegawa, Y., Kengaku, Y., Krissinel, E., Kurisu, G., Liang, Y., Liebschner, D., Mak, L. & 15 others, Markley, J. L., Moriarty, N. W., Murshudov, G. N., Noble, M., Peisach, E., Persikova, I., Poon, B. K., Sobolev, O. V., Ulrich, E. L., Velankar, S., Vonrhein, C., Westbrook, J., Wojdyr, M., Yokochi, M. & Young, J. Y., Apr 1 2019, In : Acta Crystallographica Section D: Structural Biology. 75, p. 451-454 4 p.

Research output: Contribution to journal › Letter

Open Access
Databases
Proteins
Data Curation
3 Citations (Scopus)

A Novel Acquired Exon 20 EGFR M766Q Mutation in Lung Adenocarcinoma Mediates Osimertinib Resistance but is Sensitive to Neratinib and Poziotinib

Castellano, G. M., Aisner, J., Burley, S. K., Vallat, B., Yu, H. A., Pine, S. R. & Ganesan, S., Nov 2019, In : Journal of Thoracic Oncology. 14, 11, p. 1982-1988 7 p.

Research output: Contribution to journal › Article

Exons
Mutation
Lung Neoplasms
N-(4-(3-chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide
HM781-36B
2 Citations (Scopus)

Biojava 5: A community driven open-source bioinformatics library

Lafita, A., Bliven, S., Prlić, A., Guzenko, D., Rose, P. W., Bradley, A., Pavan, P., Myers-Turnbull, D., Valasatava, Y., Heuer, M., Larson, M., Burley, S. K. & Duarte, J. M., Feb 2019, In : PLoS computational biology. 15, 2, e1006791.

Research output: Contribution to journal › Article

Open Access
bioinformatics
Bioinformatics
Computational Biology
Open Source
Libraries

Continuous Evaluation of Ligand Protein Predictions: A Weekly Community Challenge for Drug Docking

Wagner, J. R., Churas, C. P., Liu, S., Swift, R. V., Chiu, M., Shao, C., Feher, V. A., Burley, S. K., Gilson, M. K. & Amaro, R. E., Aug 6 2019, In : Structure. 27, 8, p. 1326-1335.e4

Research output: Contribution to journal › Article

Open Access
Ligands
Pharmaceutical Preparations
Proteins
Workflow
Drug Design