• 4577 Citations
  • 37 h-Index
1987 …2019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
Mycobacterium smegmatis Medicine & Life Sciences
Mycobacterium bovis Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Bacillus Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences

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Research Output 1987 2019

Advancing translational science for pulmonary nontuberculous mycobacterial infections: A road map for research

Daniel-Wayman, S., Abate, G., Barber, D. L., Bermudez, L. E., Coler, R. N., Cynamon, M. H., Daley, C. L., Davidson, R. M., Dick, T., Floto, R. A., Henkle, E., Holland, S. M., Jackson, M., Lee, R. E., Nuermberger, E. L., Olivier, K. N., Ordway, D. J., Prevots, D. R., Sacchettini, J. C., Salfinger, M. & 4 othersSassetti, C. M., Sizemore, C. F., Winthrop, K. L. & Zelazny, A. M., Apr 15 2019, In : American journal of respiratory and critical care medicine. 199, 8, p. 947-951 5 p.

Research output: Contribution to journalReview article

Lung
Infection
Research

Gut microbiota metabolite indole propionic acid targets tryptophan biosynthesis in Mycobacterium tuberculosis

Negatu, D. A., Yamada, Y., Xi, Y., Go, M. L., Zimmerman, M., Ganapathy, U., Dartois, V., Gengenbacher, M. & Dick, T., Mar 1 2019, In : mBio. 10, 2, e02781-18.

Research output: Contribution to journalArticle

Open Access
Mycobacterium tuberculosis
Tryptophan
Anthranilate Synthase
indole
propionic acid
3 Citations (Scopus)

1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity

Yang, X., Wedajo, W., Yamada, Y., Dahlroth, S. L., Neo, J. J. L., Dick, T. & Chui, W. K., Jan 20 2018, In : European Journal of Medicinal Chemistry. 144, p. 262-276 15 p.

Research output: Contribution to journalArticle

Folic Acid Antagonists
Tetrahydrofolate Dehydrogenase
Mycobacterium tuberculosis
Molecular modeling
Cytotoxicity
1 Citation (Scopus)

Impact of immunopathology on the antituberculous activity of pyrazinamide

Blanc, L., Sarathy, J. P., Cabrera, N. A., O’Brien, P., Dias‑Freedman, I., Mina, M., Sacchettini, J., Savic, R. M., Gengenbacher, M., Podell, B. K., Prideaux, B., Ioerger, T., Dick, T. & Dartois, V., Sep 1 2018, In : Journal of Experimental Medicine. 215, 8, p. 1975-1986 12 p.

Research output: Contribution to journalArticle

Pyrazinamide
Tuberculosis
Bacteriology
Mycobacterium tuberculosis
Pharmaceutical Preparations
2 Citations (Scopus)

Indolyl Azaspiroketal Mannich Bases Are Potent Antimycobacterial Agents with Selective Membrane Permeabilizing Effects and in Vivo Activity

Nyantakyi, S. A., Li, M., Gopal, P., Zimmerman, M., Dartois, V., Gengenbacher, M., Dick, T. & Go, M. L., Jul 12 2018, In : Journal of Medicinal Chemistry. 61, 13, p. 5733-5750 18 p.

Research output: Contribution to journalArticle

Mannich Bases
Anti-Bacterial Agents
Membranes
Mutation Rate
Mycobacterium