• 3899 Citations
  • 33 h-Index
1990 …2023
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Fingerprint Dive into the research topics where Tibor Rohacs is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Phosphatidylinositols Medicine & Life Sciences
Transient Receptor Potential Channels Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Type C Phospholipases Medicine & Life Sciences
Zona Glomerulosa Medicine & Life Sciences
Menthol Medicine & Life Sciences
Angiotensin II Medicine & Life Sciences
TRPV Cation Channels Medicine & Life Sciences

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Projects 2001 2023

Molecular mechanism of TRPV1 activation

Rohacs, T. & Carnevale, V.

National Institutes of Health

9/10/197/31/23

Project: Research project

Chemical activation
Electrophysiology
Mutagenesis
Wetting
Asparagine

Regulation of the Intestinal Ca2+ Channels TRPV6

Rohacs, T. & Carnevale, V.

National Institutes of Health

4/1/111/31/21

Project: Research project

Transient Receptor Potential Channels
Adenosine Triphosphate
Phosphatidylinositols
TRPV Cation Channels
Lipids
Transient Receptor Potential Channels
Phosphatidylinositols
Lipids
Type C Phospholipases
Capsaicin
Fluorescence Resonance Energy Transfer
Ion Channels
GTP-Binding Protein gamma Subunits
GTP-Binding Protein beta Subunits
Fluorescence

Research Output 1990 2019

Gαq Sensitizes TRPM8 to Inhibition by PI(4,5)P2 Depletion upon Receptor Activation

Liu, L., Yudin, Y., Nagwekar, J., Kang, C., Shirokova, N. & Rohacs, T., Jul 31 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 31, p. 6067-6080 14 p.

Research output: Contribution to journalArticle

Type C Phospholipases
G-Protein-Coupled Receptors
Menthol
Phosphatidylinositols
Hydrolysis

Molecular mechanism of TRPV2 channel modulation by cannabidiol

Pumroy, R. A., Samanta, A., Liu, Y., Hughes, T. E. T., Zhao, S., Yudin, Y., Rohacs, T., Han, S. & Moiseenkova-Bell, V. Y., Sep 2019, In : eLife. 8

Research output: Contribution to journalArticle

Cannabidiol
Modulation
Transient Receptor Potential Channels
Cryoelectron Microscopy
Lipids
1 Citation (Scopus)

Structure-based characterization of novel TRPV5 inhibitors

Hughes, T. E. T., Rosario, J. S. D., Kapoor, A., Yazici, A. T., Yudin, Y., Fluck, E. C., Filizola, M., Rohacs, T. & Moiseenkova-Bell, V. Y., Oct 2019, In : eLife. 8, e49572.

Research output: Contribution to journalArticle

Open Access
TRPV Cation Channels
Modulators
Screening
Binding Sites
Electrophysiology
1 Citation (Scopus)

The G-protein-biased agents PZM21 and TRV130 are partial agonists of μ-opioid receptor-mediated signalling to ion channels

Yudin, Y. & Rohacs, T., Jan 1 2019, In : British Journal of Pharmacology. 176, 17, p. 3110-3125 16 p.

Research output: Contribution to journalArticle

Opioid Receptors
Ion Channels
GTP-Binding Proteins
Ala(2)-MePhe(4)-Gly(5)-enkephalin
Opioid Analgesics
2 Citations (Scopus)

Tools for Understanding Nanoscale Lipid Regulation of Ion Channels

Robinson, C. V., Rohacs, T. & Hansen, S. B., Sep 1 2019, In : Trends in Biochemical Sciences. 44, 9, p. 795-806 12 p.

Research output: Contribution to journalReview article

Ion Channels
Lipids
Membranes
Cell membranes
Phosphatidylinositols