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Dive into the research topics where Yanxiang Guo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Elucidate the mechanism of autophagy in supporting Lkb1-deficient lung tumorigenesis and metastasis
Guo, Y. (CoPI) & Guo, Y. Y. (PI)
2/1/20 → 1/31/26
Project: Research project
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The role of autophagy in Kras-driven lung cancer
Guo, Y. (PI)
9/1/15 → 8/31/19
Project: Research project
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Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer
Lan, T., Arastu, S., Lam, J., Kim, H., Wang, W., Wang, S., Bhatt, V., Lopes, E. C., Hu, Z., Sun, M., Luo, X., Ghergurovich, J. M., Su, X., Rabinowitz, J. D., White, E. & Guo, J. Y., Dec 2024, In: Nature communications. 15, 1, 5857.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Role of Tumor Cell Intrinsic and Host Autophagy in Cancer
Guo, J. Y. & White, E., Jul 2024, In: Cold Spring Harbor Perspectives in Medicine. 14, 7, a041539.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors
Bhatt, V., Lan, T., Wang, W., Kong, J., Lopes, E. C., Wang, J., Khayati, K., Raju, A., Rangel, M., Lopez, E., Hu, Z. S., Luo, X., Su, X., Malhotra, J., Hu, W., Pine, S., White, E. & Guo, J. Y., Jan 2023, In: Cell Death and Disease. 14, 1, 61.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Slow TCA flux and ATP production in primary solid tumours but not metastases
Bartman, C. R., Weilandt, D. R., Shen, Y., Lee, W. D., Han, Y., TeSlaa, T., Jankowski, C. S. R., Samarah, L., Park, N. R., da Silva-Diz, V., Aleksandrova, M., Gultekin, Y., Marishta, A., Wang, L., Yang, L., Roichman, A., Bhatt, V., Lan, T., Hu, Z. & Xing, X. & 8 others, , Feb 9 2023, In: Nature. 614, 7947, p. 349-357 9 p.Research output: Contribution to journal › Article › peer-review
Open Access151 Scopus citations -
SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity
Zhong, H., Lu, W., Tang, Y., Wiel, C., Wei, Y., Cao, J., Riedlinger, G., Papagiannakopoulos, T., Guo, J. Y., Bergo, M. O., Kang, Y., Ganesan, S., Sabaawy, H. E. & Pine, S. R., Jun 30 2023, In: Oncogene. 42, 27, p. 2183-2194 12 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations