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Dive into the research topics where Zhiyuan Shen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Mechanisms of the BRCA-network in tumorigenesis and therapeutic response
Bunting, S. (CoPI), De, S. (CoPI), Ganesan, S. (CoPI), Xia, B. (CoPI), Shen, Z. (CoPI), Shen, Z. Z. (PI), Xia, B. B. (CoPI), Bunting, S. (CoPI), Ganesan, S. (CoPI) & De, S. (CoPI)
5/1/21 → 4/30/26
Project: Research project
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Project 4: The BRCA Network in Medulloblastoma Responses to Replication Stress
Shen, Z. (PI) & Shen, Z. Z. (PI)
4/1/21 → 4/30/26
Project: Research project
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Regulation of Ku70 methylation and functions by SETD4
Shen, Z. (CoPI) & Shen, Z. Z. (PI)
2/1/21 → 1/31/26
Project: Research project
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Molecular modulators of radiation-induced chromosome instability and hematopoietic damage
Shen, Z. (CoPI) & Shen, Z. Z. (PI)
5/1/15 → 6/30/26
Project: Research project
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Lymphatic endothelial mTORC1 instructs metabolic and developmental signaling during lymphangiogenesis
Han, F., Simeroth, S., Zhu, J., Gryniuk, I., Pranay, A., Chen, W., Wang, Y., Cai, Y., Shen, Z., Wang, G., Griffin, C. T., Xia, L. & Yu, P., Sep 8 2025, In: Developmental Cell. 60, 17, p. 2331-2347.e6Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The mammalian Ku70 C-terminus SAP domain is required to repair DNA damage
Wang, Y., Czap, M. S., Kim, H., Masaka, P. M., Wang, H., Beg, M. A., Lu, H., Liu, J., Chang, Y. C., Romanienko, P. J., Montagna, C. & Shen, Z., Jun 24 2025, In: Nucleic acids research. 53, 11, gkaf499.Research output: Contribution to journal › Article › peer-review
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Medulloblastomas Initiated by Homologous Recombination Defects in Mice
Lu, H., Wang, Y., Chaudhary, S., Balaga, V., Ke, H., Shi, F., Liu, J., Huo, Y., Romanienko, P. J., Xia, B., De, S., Chan, C. S. & Shen, Z., Nov 2024, In: American Journal of Pathology. 194, 11, p. 2007-2022 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Disrupted BRCA1-PALB2 interaction induces tumor immunosuppression and T-lymphocyte infiltration in HCC through cGAS-STING pathway
Ma, H., Kang, Z., Foo, T. K., Shen, Z. & Xia, B., Jan 2023, In: Hepatology. 77, 1, p. 33-47 15 p.Research output: Contribution to journal › Article › peer-review
Open Access71 Scopus citations -
SETD4-mediated KU70 methylation suppresses apoptosis
Wang, Y., Liu, B., Lu, H., Liu, J., Romanienko, P. J., Montelione, G. T. & Shen, Z., May 10 2022, In: Cell Reports. 39, 6, 110794.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations