Acute Cognitive Impairments Following Exposure to Inhaled CO2: Translating Mouse Mechanisms to Humans

Project Details

Description

Project Summary/Abstract Humans in developed countries spend 80% of their time indoors. Carbon dioxide (CO2) is a product of respiration, expired at a concentration of 40,000 ppm, leading to higher levels indoors than outdoors. CO2 is widely regarded as nontoxic. However, three human experimental studies using highly sensitive tests of cognitive function including an airline flight simulator, reported concentration-related decrements in higher cognitive function during 2 hr. exposures to elevated, but real-world CO2 concentrations (
StatusFinished
Effective start/end date8/23/227/31/24

Funding

  • National Institute of Environmental Health Sciences: $196,250.00
  • National Institute of Environmental Health Sciences: $235,500.00

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