ANALYSIS OF CELLS AND CHROMOSOMES WITH A CELL SORTER

Project Details

Description

This is a request for an instrumentation system comprising an
Ortho-Cyto-fluorograph System 50 H with Lexel 95-4 4W Laser, and a Model
2151 Data Handling System, from Ortho Diagnostic Systems, Inc. The system
will be located at UMDNJ-Rutgers Medical School, but will be shared by
investigators at UMDNJ-Rutgers Medical School and at Rutgers University
whose research encompasses the following areas: (1) Isolation and
characterization of hypothalamic nerve cells using monoclonal antibodies to
cell surface antigens, (2) the chromosomal organization of collagen gene
families, (3) the developmentally regulated expression of collagen genes,
(4) modulation of phagocyte activities by monoclonal antibodies, and (5)
expression of vaccinia virus antigens on the surface of infected cells.

The flow cytometer/cell sorter will dramatically extend the research
capabilities of investigators in several departments immediately. It will
foster work in molecular genetics and molecular cell biology at the most
advanced "state-of-the-art" technical level. Thus, it will help initiate
some of the "high technology" activities that will be coordinated and
further supported by the Center for Biotechnology and Medicine planned by
the State of New Jersey for the UMDNJ-Rutgers Medical School/Rutgers
University Campus.
StatusFinished
Effective start/end date1/1/901/1/90

ASJC

  • Cell Biology

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