DEVELOPMENT OF DATABASE FOR GENETIC EPIDEMIOLOGICAL STUDIES

Project Details

Description

MEDIB has begun developing, implementing and documenting a
comprehensive laboratory data management system. This system will be
used for the management of clinical, pedigree and genotype data for
gene mapping studies. The database format shall be used for multiple
databases (among them, juvenile periodontitis, cleft lip and palate
and Kartagener Syndrome). The databases and programs will be
implemented in 4th Dimension (4D) on Mackintosh computers. Mr.
George Tiller, 4D Register Developer, is cooperating with MEDIB staff
to develop appropriate procedures and documentation. The completed
system will integrate and manage clinical information, family
histories, and marker-allele typing as well as provide interactive
procedures for 1) extensive error checking 2) generation of formatted
files suitable for input to various linkage analysis programs, and 3)
provide primer inventories and for tracking DNA samples and the cell
lines produced from them. Future effects will include developing
procedures for 1) checking genetic incompatibilities and 2) rounding
and banning allele sizes for more direct input into the database.
StatusNot started

Funding

  • National Institute of Dental and Craniofacial Research
  • National Institute of Dental and Craniofacial Research
  • National Institute of Dental and Craniofacial Research

ASJC

  • Genetics
  • Medicine(all)
  • Dentistry(all)

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