DEVELOPMENTAL EFFECTS OF PRENATAL COCAINE EXPOSURE

  • Lewis, Michael (PI)
  • Carmody, Dennis (CoI)
  • Bennett, David (CoI)
  • Kestler, Lisa (CoI)

Project Details

Description

Use of cocaine has skyrocketed, and an increasing number of pregnant
women are abusing this drug. Studies of neonates exposed to cocaine
indicate neurobehavioral problems, however long-term follow-up studies
are sparse. The broad objective of this study is to ascertain long- term
consequences of cocaine exposure on specific cognitive and
social/emotional competencies. The specific aims are 1) to determine the
cognitive functions related specifically to prenatal cocaine exposure;
and 2) to control the impact of the environment on development when
assessing the effects of cocaine exposure. Pregnant women attending prenatal clinics for low income, high-risk
patients in Trenton, NJ, and Northwest Philadelphia will be approached
for participation in the study. Drug addiction counselors, maternal and
newborn urine screens will help determine which women have been using
cocaine during their pregnancies A greater number of non-substance
abusing women will be approached as matched controls. Only fullterm,
relatively healthy babies will be included in the sample. A sample of
245 cocaine-exposed and 265 control babies is anticipated. Multiple
measures of learning, attentional processes, language, neuromotor ability
and social/emotional behavior will be obtained at 7 time points from
birth through 30 months of age. Studying these different aspects of
competence permits an understanding of specific developmental effects of
prenatal cocaine exposure. Detailed measures of the family environment,
including extent of life stress, social support and quality of the
caregiver-child interaction also will be collected. This study will work through programs and agencies designed to locate,
follow, and provide intervention to high-risk pregnant women and mothers
in Trenton and a cocaine treatment program for pregnant women in
Philadelphia. A National Advisory Committee will be convened each year
to review and guide the study.
StatusFinished
Effective start/end date8/1/924/30/15

Funding

  • National Institutes of Health: $60,574.00
  • National Institutes of Health: $637,629.00
  • National Institutes of Health
  • National Institutes of Health: $812,361.00
  • National Institutes of Health: $792,138.00
  • National Institutes of Health: $968,293.00
  • National Institutes of Health
  • National Institutes of Health: $799,982.00
  • National Institutes of Health: $807,654.00
  • National Institutes of Health: $1,122,800.00
  • National Institutes of Health: $824,410.00
  • National Institutes of Health: $72,400.00
  • National Institutes of Health: $859,211.00
  • National Institutes of Health: $1,173,296.00
  • National Institutes of Health: $9,850.00
  • National Institutes of Health: $40,603.00
  • National Institutes of Health: $950,288.00
  • National Institutes of Health
  • National Institutes of Health: $8,060.00
  • National Institutes of Health: $1,092,547.00
  • National Institutes of Health: $4,900.00
  • National Institutes of Health: $983,990.00
  • National Institutes of Health
  • National Institutes of Health: $822,598.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $71,221.00
  • National Institutes of Health: $699,463.00
  • National Institutes of Health
  • National Institutes of Health: $2,930.00
  • National Institutes of Health: $823,488.00
  • National Institutes of Health
  • National Institutes of Health: $5,366.00

ASJC

  • Medicine(all)

Fingerprint Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.