NEURAL AND ENDOCRINE BASIS OS SELF-STIMULATION OF OVARIAN DEVELOPMENT/DOVES

  • Zaborszky, Laszlo (PI)
  • Komisaruk, Barry (PI)
  • Jordan, Frank (PI)
  • Cheng, Mei Fang (PI)
  • Morrell, Juani (PI)
  • Hart, Ronald (PI)
  • Whipple, Beverly Beverly (PI)
  • Komisaruk, Barry (PI)
  • Frenkel, Gerald (PI)
  • Komisaruk, Barry (PI)
  • Mendelsohn, Richard (PI)
  • Mendelsohn, Richard (PI)
  • Bonder, Edward (PI)
  • Gluck, Mark (PI)
  • Huskey, W (PI)
  • Jordan, Frank (PI)
  • KOMISARUK, BARRY RICHARD (PI)
  • KOMISARUK, BARRY RICHARD (PI)
  • FEDER, HARVEY (PI)
  • GULICK, ELSIE (PI)
  • JONAKAIT, MILLER (PI)
  • ROSENBLATT, JAY (PI)
  • Weis, Judith (PI)
  • ROSENBLATT, JAY (PI)
  • Fryer, Rodney (PI)
  • Gilchrist, Alan (PI)
  • Swann, Jennifer (PI)
  • Buzaki, Gyorgy (PI)
  • Ganea, Doina (PI)
  • Lev, Elise (PI)
  • Shaw, Earl (PI)
  • Siegal, Ralph (PI)
  • Stein, Donald (PI)
  • Tepper, James (PI)
  • Weis, Judith (PI)
  • Whipple, Beverly (PI)
  • Jordan, Frank (PI)
  • ROSENBLATT, JAY (PI)
  • Fryer, Rodney (PI)
  • Gilchrist, Alan (PI)
  • Swann, Jennifer (PI)
  • Buzaki, Gyorgy (PI)
  • Ganea, Doina (PI)
  • Gluck, Mark (PI)
  • Lev, Elise (PI)
  • Shaw, Earl (PI)
  • Siegal, Ralph (PI)
  • Stein, Donald (PI)
  • Tepper, James (PI)
  • Weis, Judith (PI)

Project Details

Description

It has been shown in previous studies that electrolytic lesions in
the estrogen-sensitive nucleus intercollicularis (ICo) disrupt
female nest-coos and male courtship induced ovarian development
in the ring dove. In this proposal we analyze the underlying neural
circuitry and neuroendocrine mechanisms with the methods for
electrolytic lesion, selective chemical lesion, electrophysiological
recordings and immunohistochemistry. Three interrelated studies
are proposed: (1) Study of the role of the ICo neurons, (2) Role of
telencephalic centers, such as nucleus taenia, an estrogen
sensitive region which sends projections to the ICo, and (3) Role
of the ICo projections to pre-optic-anterior hypothalamic region,
an area concentrated with gonadotrophin releasing hormone
neurons, with respect to the production of nest-coo display (vocal
and posture component) and ovarian response to different coos.

The long-term goal of these studies is to delineate the neural and
endocrine mechanisms underlying the behaviorally mediated
ovarian activity. These lines of studies may eventually help to
understand and control of well-known clinical phenomenon such as
the promotion of a woman's chance to conceive a child by
adopting one.
StatusFinished
Effective start/end date1/1/0112/31/99

Funding

  • National Institute of General Medical Sciences
  • National Institute of General Medical Sciences
  • National Institute of General Medical Sciences
  • National Institute of General Medical Sciences
  • National Institute of General Medical Sciences
  • National Institute of General Medical Sciences
  • National Institute of General Medical Sciences

ASJC

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Animal Science and Zoology
  • Clinical Neurology
  • Endocrine and Autonomic Systems
  • Nephrology
  • Neurology
  • Genetics
  • Molecular Biology
  • Structural Biology
  • Physiology
  • Immunology
  • Neuroscience(all)
  • Nursing(all)
  • Psychiatry and Mental health
  • General
  • Radiation
  • Ophthalmology
  • Biochemistry
  • Spectroscopy
  • Oncology
  • Cancer Research
  • Catalysis
  • Pediatrics, Perinatology, and Child Health
  • Embryology

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