Spatial frequency contributions to contour integration deficits in schizophrenia

  • Keane, Brian (PI)
  • KEANE, BRIAN PATRICK (PI)
  • KEANE, BRIAN PATRICK (PI)

    Project Details

    Description

    DESCRIPTION (provided by applicant): Contour integration (CI)-for the purposes of the present application-refers to the ability to represent spatially segregated edges as a single continuous contour. Numerous studies suggest that people with schizophrenia (SZ) are impaired at contour integration, but the mechanisms, time-course, and clinical implications of the impairment are just beginning to be explored. To shed light on this issue, we conduct a two phase psychophysical investigation. In the first phase, we will satisfy NIMH Strategy 1.1, and clarify the neural mechanisms behind the deficit (Aim 1). Clinical CI studies to date have almost exclusively employed lower spatial frequency contour elements (
    StatusFinished
    Effective start/end date1/1/1212/31/14

    Funding

    • National Institute of Mental Health: $52,860.00
    • National Institute of Mental Health: $56,978.00
    • National Institute of Mental Health: $22,596.00
    • National Institute of Mental Health: $30,446.00

    ASJC

    • Medicine(all)
    • Psychiatry and Mental health
    • Biochemistry, Genetics and Molecular Biology(all)
    • Neuroscience(all)

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