(-)-3,6-dioxo-5β-cholanic acid: Hydrogen bonding in the hemihydrate of a steroidal diketo acid

Hugh W. Thompson, Roger A. Lalancette, Andrew P.J. Brunskill

Research output: Contribution to journalArticlepeer-review

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Abstract

The hemihydrate of the title diketo acid, C24H36O4·0.5H2O, forms hydrogen-bonded carboxyl dimers related by a C2 axis at crystallographic sites on the a and b edges of the chosen cell [O...O = 2.643 (7) and 2.716 (7) Å]. The ketone ends of the molecules approach each other at sites near (1/2,1/2,1/2), (1/2,0,1/2), (0,0,1/2) and (0,1/2,1/2) in an interleaved arrangement incorporating partial-occupancy water hydrogen bonded to the B-ring ketone.

Original languageEnglish (US)
Pages (from-to)632-633
Number of pages2
JournalActa Crystallographica Section C: Crystal Structure Communications
Volume57
Issue number5
DOIs
StatePublished - May 2001

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology

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