A dietary regimen alters hepatocyte plasma membrane lipid fluidity and ameliorates ethinyl estradiol cholestasis in the rat

Judith Storch, David Schachter

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A dietary regimen which induces hepatic fatty acyl desaturase activities increases the lipid fluidity of hepatocyte plasma membranes, both in normal rats and in animals treated with ethinyl estradiol to produce cholestasis. In the cholestatic animals the fluidity change is accompanied by a significant increase in bile flow rate of approx. 33%.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalBBA - General Subjects
Volume798
Issue number1
DOIs
StatePublished - Mar 22 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology

Keywords

  • (Rat)
  • Cholestatis
  • Diet
  • Ethinyl estradiol
  • Lipid fluidity

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