A dietary regimen alters hepatocyte plasma membrane lipid fluidity and ameliorates ethinyl estradiol cholestasis in the rat

Judith Storch; David Schachter

doi:10.1016/0304-4165(84)90021-7

A dietary regimen alters hepatocyte plasma membrane lipid fluidity and ameliorates ethinyl estradiol cholestasis in the rat

Judith Storch, David Schachter

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

A dietary regimen which induces hepatic fatty acyl desaturase activities increases the lipid fluidity of hepatocyte plasma membranes, both in normal rats and in animals treated with ethinyl estradiol to produce cholestasis. In the cholestatic animals the fluidity change is accompanied by a significant increase in bile flow rate of approx. 33%.

Original language	English (US)
Pages (from-to)	137-140
Number of pages	4
Journal	BBA - General Subjects
Volume	798
Issue number	1
DOIs	https://doi.org/10.1016/0304-4165(84)90021-7
State	Published - Mar 22 1984
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biophysics
Biochemistry
Molecular Biology

Keywords

(Rat)
Cholestatis
Diet
Ethinyl estradiol
Lipid fluidity

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10.1016/0304-4165(84)90021-7

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abstract = "A dietary regimen which induces hepatic fatty acyl desaturase activities increases the lipid fluidity of hepatocyte plasma membranes, both in normal rats and in animals treated with ethinyl estradiol to produce cholestasis. In the cholestatic animals the fluidity change is accompanied by a significant increase in bile flow rate of approx. 33%.",

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AU - Storch, Judith

AU - Schachter, David

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Y1 - 1984/3/22

N2 - A dietary regimen which induces hepatic fatty acyl desaturase activities increases the lipid fluidity of hepatocyte plasma membranes, both in normal rats and in animals treated with ethinyl estradiol to produce cholestasis. In the cholestatic animals the fluidity change is accompanied by a significant increase in bile flow rate of approx. 33%.

AB - A dietary regimen which induces hepatic fatty acyl desaturase activities increases the lipid fluidity of hepatocyte plasma membranes, both in normal rats and in animals treated with ethinyl estradiol to produce cholestasis. In the cholestatic animals the fluidity change is accompanied by a significant increase in bile flow rate of approx. 33%.

KW - (Rat)

KW - Cholestatis

KW - Diet

KW - Ethinyl estradiol

KW - Lipid fluidity

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ER -

A dietary regimen alters hepatocyte plasma membrane lipid fluidity and ameliorates ethinyl estradiol cholestasis in the rat

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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