A little bit of sugar makes Polycomb better

Yuri B. Schwartz, Vincenzo Pirrotta

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Transcriptional repression by Polycomb group (PcG) proteins is now sweetened by the discovery of the essential role of O-GlcNAc glycosylation in the process. PcG protein polyhomeotic may be the key target, but alternative or additional functions including repression of transcription through glycosylation of the C-terminal domain of RNA polymerase II are also possible.

Original languageEnglish (US)
Pages (from-to)11-12
Number of pages2
JournalJournal of molecular cell biology
Volume1
Issue number1
DOIs
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics
  • Cell Biology

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