A novel method for the preparation of adenosine 3′5′ cyclic phosphate labelled with 14C or 3H

V. N. Pandey, C. K.K. Nair, D. S. Pradhan

Research output: Contribution to journalArticlepeer-review

Abstract

High yields of cyclic AMP (cAMP) and cyclic GMP (cGMP) could be obtained by near quantitative conversions of adenine and guanine by aerobically‐grown nonproliferating cells of Corynebacterium murisepticum. The procedure is especially suited for the preparation of 14C or 3H labelled cAMP and cGMP from respective purine base precursors.

Original languageEnglish (US)
Pages (from-to)385-389
Number of pages5
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume20
Issue number3
DOIs
StatePublished - Mar 1983
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

Keywords

  • Adenine
  • Corynebacteriummurisepticum
  • Hypoxanthine
  • cyclic AMP
  • cyclic GMP

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