A Randomized Clinical Trial of a Parent-Focused Social-Cognitive Processing Intervention for Caregivers of Children Undergoing Hematopoetic Stem Cell Transplantation

Sharon Manne, Laura Mee, Abraham Bartell, Stephen Sands, Deborah A. Kashy

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Objective: Providing care to one's child during and after a hematopoietic stem cell transplant (HSCT) is a universally stressful experience, but few psychological interventions have been developed to reduce caregiver distress. The goal of this study was to test the efficacy of a brief cognitive-behavioral intervention delivered to primary caregivers. Method: Two hundred eighteen caregivers were assigned either best-practice psychosocial care (BPC) or a parent social-cognitive intervention program (P-SCIP). The 5 session P-SCIP was delivered during the HSCT hospitalization. Caregivers completed measures of distress, optimism, coping, and fear appraisals preintervention, 1, 6 months, and 1 year. Results: P-SCIP reduced caregiver's distress significantly more than BPC between the pretransplant assessment (Time 1) and 1-month follow-up assessment (Time 2). P-SCIP had a stronger effect than BPC among caregivers who began the hospitalization reporting higher depression and anxiety, and among caregivers whose children developed graft-versus-host disease (GvHD). Long-term treatment effects of P-SCIP were seen in traumatic distress among caregivers who reported higher anxiety pretransplant as well as among caregivers whose children had GvHD at HSCT discharge. Conclusions: Screening caregivers for elevations in pretransplant anxiety and targeting interventions specifically to these caregivers, as well as targeting caregivers to children who develop GvHD, may prove beneficial.

Original languageEnglish (US)
Pages (from-to)389-401
Number of pages13
JournalJournal of Consulting and Clinical Psychology
Volume84
Issue number5
DOIs
StatePublished - May 1 2016

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

Keywords

  • behavioral intervention
  • caregivers
  • parents
  • pediatric transplantation

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