TY - JOUR
T1 - A randomized controlled trial of an HIV/AIDS Symptom Management Manual for depressive symptoms
AU - Eller, Lucille S.
AU - Kirksey, Kenn M.
AU - Nicholas, Patrice K.
AU - Corless, Inge B.
AU - Holzemer, William L.
AU - Wantland, Dean J.
AU - Willard, Suzanne S.
AU - Robinson, Linda
AU - Hamilton, Mary Jane
AU - Sefcik, Elizabeth F.
AU - Moezzi, Shahnaz
AU - Mendez, Marta Rivero
AU - Rosa, Maria
AU - Human, Sarie
N1 - Funding Information:
This project was supported in part by NIH/NCRR UCSF-CTSI Grant Number UL1 RR024131; NIH/NINR T32NR007081 (HIV/AIDS Nursing Care and Prevention); Case Western Reserve University/Cleveland Clinic & CTSA Grant Number UL1 RR024989; Academic Research Enhancement Award, NIH 1R15NR011130; International Pilot Award, University of Washington Center for AIDS Research; University of British Columbia School of Nursing Helen Shore Fund; A Small Project Grant from the Duke University School of Nursing Office of Research Affairs; a faculty grant from the MGH Institute for H ealth Professions. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH or any other funders.
PY - 2013/4/1
Y1 - 2013/4/1
N2 - Depressive symptoms are highly prevalent, underdiagnosed, and undertreated in people living with HIV/AIDS (PLWH), and are associated with poorer health outcomes. This randomized controlled trial examined the effects of the HIV/AIDS Symptom Management Manual self-care symptom management strategies compared with a nutrition manual on depressive symptoms in an international sample of PLWH. The sample consisted of a sub-group (N=222) of participants in a larger study symptom management study who reported depressive symptoms. Depressive symptoms of the intervention (n=124) and control (n=98) groups were compared over three months: baseline, one-month, and two-months. Use and effectiveness of specific strategies were examined. Depressive symptom frequency at baseline varied significantly by country (χ 2 12.9; p=0.04). Within the intervention group there were significant differences across time in depressive symptom frequency [F(2, 207) = 3.27, p=0.05], intensity [F(2, 91) = 4.6, p=0.01], and impact [F(2, 252) = 2.92, p= 0.05), and these were significantly lower at one month but not at two months, suggesting that self-care strategies are effective in reducing depressive symptoms, however effects may be short term. Most used and most effective self-care strategies were distraction techniques and prayer. This study suggests that people living with HIV can be taught and will employ self-care strategies for management of depressive symptoms and that these strategies are effective in reducing these symptoms. Self-care strategies are noninvasive, have no side-effects, and can be readily taught as an adjunct to other forms of treatment. Studies are needed to identify the most effective self-care strategies and quantify optimum dose and frequency of use as a basis for evidence-based practice.
AB - Depressive symptoms are highly prevalent, underdiagnosed, and undertreated in people living with HIV/AIDS (PLWH), and are associated with poorer health outcomes. This randomized controlled trial examined the effects of the HIV/AIDS Symptom Management Manual self-care symptom management strategies compared with a nutrition manual on depressive symptoms in an international sample of PLWH. The sample consisted of a sub-group (N=222) of participants in a larger study symptom management study who reported depressive symptoms. Depressive symptoms of the intervention (n=124) and control (n=98) groups were compared over three months: baseline, one-month, and two-months. Use and effectiveness of specific strategies were examined. Depressive symptom frequency at baseline varied significantly by country (χ 2 12.9; p=0.04). Within the intervention group there were significant differences across time in depressive symptom frequency [F(2, 207) = 3.27, p=0.05], intensity [F(2, 91) = 4.6, p=0.01], and impact [F(2, 252) = 2.92, p= 0.05), and these were significantly lower at one month but not at two months, suggesting that self-care strategies are effective in reducing depressive symptoms, however effects may be short term. Most used and most effective self-care strategies were distraction techniques and prayer. This study suggests that people living with HIV can be taught and will employ self-care strategies for management of depressive symptoms and that these strategies are effective in reducing these symptoms. Self-care strategies are noninvasive, have no side-effects, and can be readily taught as an adjunct to other forms of treatment. Studies are needed to identify the most effective self-care strategies and quantify optimum dose and frequency of use as a basis for evidence-based practice.
KW - HIV disease
KW - depressive symptoms
KW - randomized controlled trial
KW - self-management
KW - symptom management
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UR - http://www.scopus.com/inward/citedby.url?scp=84875346622&partnerID=8YFLogxK
U2 - 10.1080/09540121.2012.712662
DO - 10.1080/09540121.2012.712662
M3 - Article
C2 - 22880943
AN - SCOPUS:84875346622
SN - 0954-0121
VL - 25
SP - 391
EP - 399
JO - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
JF - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
IS - 4
ER -