A retrofit strategy to achieve "Fast, Flexible, Future (F3)" pharmaceutical production processes

Ravendra Singh, Raquel Rozada-Sanchez, Tim Wrate, Frans Muller, Krist V. Gernaey, Rafiqul Gani, John M. Woodley

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In the work reported here, a substrates adoption methodology for a series of similar substrates has been developed as part of a retrofit strategy. The objective is to achieve "fast, flexible and future" pharmaceutical production processes by adapting a generic modular process-plant template. Application of the methodology is illustrated through a case study from the pharmaceutical industry. Use of computer-aided models, methods and tools as part of the methodology is also highlighted.

Original languageEnglish (US)
Pages (from-to)291-295
Number of pages5
JournalComputer Aided Chemical Engineering
StatePublished - 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Computer Science Applications


  • Fast
  • Flexible
  • Retrofit strategy
  • Substrates adoption methodology

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